Results 271 to 280 of about 66,303 (295)
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Prognostic Implication of Immunohistochemical Runx2 Expression in Osteosarcoma

Tumori Journal, 2009
Aims and background Osteosarcoma is the most common primary bone malignancy. Many genetic markers have proven prognostic value in osteosarcoma and studies are under way to determine their potential application as specific therapeutic targets. Runx2, Indian hedgehog (IHH), and Sox9 are proteins that play major roles in bone formation and tumorigenesis ...
Kyu Yeoun Won   +2 more
openaire   +2 more sources

Hakai, a novel Runx2 interacting protein, augments osteoblast differentiation by rescuing Runx2 from Smurf2‐mediated proteasome degradation

Journal of Cellular Physiology
AbstractRunt‐related transcription factor 2 (Runx2) is a key regulator of osteoblast differentiation and bone formation. In Runx2‐deficient embryos, skeletal development ceases at the cartilage anlage stage. These embryos die of respiratory failure upon birth and display a complete absence of bone and cartilage mineralization. Here, we identified Hakai,
Vishal Upadhyay   +9 more
openaire   +2 more sources

Transcriptional regulation by RUNX2

Reactome - a curated knowledgebase of biological pathways, 2017
openaire   +1 more source

RUNX2 and Cleidocranial Dysplasia

2016
Lindsay C. Burrage   +3 more
openaire   +1 more source

Whole Aspect of Runx2 Functions in Skeletal Development

International Journal of Molecular Sciences, 2022
Toshihisa Komori
exaly  

RUNX2

2018
openaire   +1 more source

Regulation of Proliferation, Differentiation and Functions of Osteoblasts by Runx2

International Journal of Molecular Sciences, 2019
Toshihisa Komori
exaly  

Mitotic occupancy and lineage-specific transcriptional control of rRNA genes by Runx2

Nature, 2007
Jitesh Pratap   +2 more
exaly  

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