Results 271 to 280 of about 69,808 (343)

Ufl1-Mediated UFMylation Sustains Amelogenesis by Stabilizing RUNX2. [PDF]

FASEB J
Liu D, Chen L, Xu H, Yang X, Wang K, Wang M, Zhu XJ.   +6 more
europepmc   +1 more source

Shared molecular framework and bidirectional effects of osteoporosis on periodontal disease and dental implant therapy in the elderly

Periodontology 2000, EarlyView.
Abstract Objectives This review synthesizes evidence regarding the prevalence, epidemiological associations, and mechanistic pathways between osteoporosis, periodontal disease, and dental implant therapy. Materials and Methods A literature review was conducted to identify studies focused on: osteoporosis, periodontal disease, and dental implants ...
Samin Sirous, Jaclyn C. Chalmers, Pin‐Ying Li, Yumna Subhani, Yvonne L. Hernandez‐Kapila   +4 more
wiley   +1 more source

EYA1 regulates CIITA phosphorylation to promote EYA1-CIITA-Runx2 complex formation and extracellular matrix integrity in osteoarthritis. [PDF]

Biol Direct
Nie G, Li Y, Zhao H, Wang D, Zhang Y, Yang X, Wen X.   +6 more
europepmc   +1 more source

Understanding extracellular vesicles in antiaging

Periodontology 2000, EarlyView.
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad, Nathan E. Estrin, Anton Sculean, Richard J. Miron   +3 more
wiley   +1 more source

Sirt1 attenuates calcific aortic valve disease by inhibiting ferroptosis and enhancing mitochondrial function via the activation of the Nrf2/HO‑1/FTH1 axis. [PDF]

Int J Mol Med
Yan F, Shi L, Wang Y, Zhao Y, Wu Y, Xian D, Liang Y, Wang N, Cui H, Zhang M.   +9 more
europepmc   +1 more source

Metabolic reprogramming of the immune response in periodontitis

Periodontology 2000, EarlyView.
Abstract Objective Periodontitis, a highly prevalent chronic inflammatory disease, is characterized by the progressive destruction of the tooth‐supporting tissues, ultimately causing tooth loss. In recent years, the emerging field of immunometabolism has revealed that immune cell function is tightly regulated by intracellular metabolic pathways that ...
Rafael Scaf de Molon, Melissa Grant, Iain Chapple, Joao Paulo Steffens   +3 more
wiley   +1 more source

How Allometry and Sexual Dimorphism Influence Cortical Bone Morphology at the Mandibular Symphysis in Modern Humans: A Comparative Study Using Elliptic Fourier Descriptors

American Journal of Biological Anthropology, Volume 191, Issue 3, November 2026.
ABSTRACT Objectives The modern human mandibular symphysis displays a mental prominence, a unique trait in the human lineage. Beyond this shared pattern, considerable variability in shape and metrics exists. This heterogeneity is thought to result from multiple mechanisms, including biomechanical compensation, allometric and dietary effects, population ...
Carla Degabriel, Ana Ribeiro, Anaïs Cavaré, Christine Couture, Pierre‐Hadrien Decaup   +4 more
wiley   +1 more source

Diminished RELB impairs osteogenesis in mature periodontal ligament stem cells. [PDF]

Stem Cell Reports
Shao X, Wu F, Song Y, Gao P, Qi K, Wang L.   +5 more
europepmc   +1 more source