Results 41 to 50 of about 209,148 (295)

Thermal Breakage and Self-Healing of a Polymer Chain under Tensile Stress

open access: yes, 2010
We consider the thermal breakage of a tethered polymer chain of discrete segments coupled by Morse potentials under constant tensile stress. The chain dynamics at the onset of fracture is studied analytically by Kramers-Langer multidimensional theory and
Dimitrov, D. I.   +4 more
core   +1 more source

Dynamic rupture along bimaterial interfaces in 3D

open access: yesGeophysical Research Letters, 2007
We perform numerical simulations of dynamic rupture propagation on a plane in a model consisting of two different elastic half spaces connected via a planar frictional interface governed by regularized Coulomb friction. Therefore, ruptures in this study are purely driven by the presence of a material contrast.
Brietzke, G., Cochard, A., Igel, H.
openaire   +4 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Focal adhesions as mechanosensors: the two-spring model [PDF]

open access: yes, 2004
Adhesion-dependent cells actively sense the mechanical properties of their environment through mechanotransductory processes at focal adhesions, which are integrin-based contacts connecting the extracellular matrix to the cytoskeleton.
Schwarz, Ulrich S.   +2 more
core   +2 more sources

Dynamic rupture of polymer–metal bilayer plates

open access: yesInternational Journal of Solids and Structures, 2008
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
McShane, G.J.   +5 more
openaire   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

3D Linked Subduction, Dynamic Rupture, Tsunami, and Inundation Modeling: Dynamic Effects of Supershear and Tsunami Earthquakes, Hypocenter Location, and Shallow Fault Slip

open access: yesFrontiers in Earth Science, 2021
Physics-based dynamic rupture models capture the variability of earthquake slip in space and time and can account for the structural complexity inherent to subduction zones.
Sara Aniko Wirp   +8 more
doaj   +1 more source

Rupture-dependent breakdown energy in fault models with thermo-hydro-mechanical processes [PDF]

open access: yesSolid Earth, 2020
Substantial insight into earthquake source processes has resulted from considering frictional ruptures analogous to cohesive-zone shear cracks from fracture mechanics.
V. Lambert, N. Lapusta, N. Lapusta
doaj   +1 more source

The dependence of the dry friction threshold on rupture dynamics

open access: yes, 2011
The static friction coefficient between two materials is considered to be a material constant. We present experiments demonstrating that the ratio of shear to normal force needed to move contacting blocks can, instead, vary systematically with ...
Ben-David, Oded, Fineberg, Jay
core   +1 more source

Intraoperative rupture cerebral aneurysm and computational flow dynamics

open access: yesAsian Journal of Neurosurgery, 2018
Intraoperative aneurysmal rupture (IAR) is the most fearsome complication of aneurysm surgery. IAR associates with high morbidity and mortality. In recent years, we have many studies regarding using computational fluid dynamics (CFD) in aneurysm surgery.
Senko, Ilya   +7 more
openaire   +3 more sources

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