Results 51 to 60 of about 202,733 (217)
FEBS Open Bio, EarlyView.Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin +12 more
wiley +1 more source
Numerical Simulation and Analysis of the Manufacturing Process of Pre-Bulged Rupture Discs
Applied SciencesRupture discs, also known as bursting discs, are indispensable components in fluid-operated systems providing effective protection against hazardous over-pressure or partial vacuum.
Benjamin Treude +2 more
doaj +1 more source
How Does Dissipation Affect the Transition from Static to Dynamic Macroscopic Friction?
Lubricants, 2015 Description of the transitional process from a static to a dynamic frictional regime is a fundamental problem of modern physics. Previously, we developed a model based on the well-known Frenkel-Kontorova model to describe dry macroscopic friction.
Naum I. Gershenzon +2 more
doaj +1 more source
Spontaneous splenic rupture 1 week after laparoscopic appendectomy due to acute appendicitis
Journal of Minimal Access Surgery, 2020 Spontaneous splenic rupture is a rare entity that requires high index of suspicion for diagnosis. Usually, it occurs due to underlying pathology that could be inflammatory, neoplastic or infectious.
Jurij Janez
doaj +1 more source
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
Wire Rupture Optimization in Wire Electrical Discharge Machining using Taguchi Approach
MATEC Web of Conferences, 2017 Wire electrical discharge machining (WEDM) is one of the most important nontraditional machining process that is well-known for cutting difficult to machine materials. The wire electrode along with machining parameters control the WEDM process.
Maher Ibrahem +2 more
doaj +1 more source
How phagocytic cells kill bacteria: Lessons from a professional killer
FEBS Open Bio, EarlyView.How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley +1 more source
Shock and Vibration, 2018 In order to explore the mechanism of floor dynamic rupture, the current study adopts a thin plate model to further investigate the condition of floor failure.
Guangjian Liu +5 more
doaj +1 more source
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source