Results 71 to 80 of about 11,434,443 (306)

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

Productive RUPture: activation of transcription factors by proteasomal processing

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2004
Proteasomes usually degrade proteins completely into small peptides. In a few cases, however, proteasomal degradation rather results in protein processing, thereby yielding proteins of different biological activity. This process, termed "regulated ubiquitin/proteasome-dependent processing" or RUP, is essential for the function of certain transcription ...
Rape, M., Jentsch, S.
openaire   +3 more sources

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

A multiple asymmetric bilateral rupture sequence derived from the peculiar tele-seismic P-waves of the 2025 Mandalay, Myanmar earthquake

Seismica
A large strike-slip earthquake occurred in central Myanmar on March 28, 2025. The aftershock distribution suggests that the rupture of the mainshock propagated mainly to the south. However, a large-amplitude phase lasting 20 s, followed by a short-period
Naohiro Inoue, Ryo Yamaguchi, Yuji Yagi, Ryo Okuwaki, Enescu Bogdan, Tira Tadapansawut   +5 more
doaj   +1 more source

Source rupture process of the Kocaeli, Turkey, earthquake of August 17, 1999, obtained by joint inversion of near‐field data and teleseismic data

Geophysical Research Letters, 2000
The rupture process of the 1999 Turkey earthquake is examined using both near‐field strong motion data and teleseismic body wave data. The derived source parameters are as follows: (strike, dip, slip) = (268°, 86°, 180°), nearly pure strike‐slip; the ...
Yuji Yagi, Masayuki Kikuchi
doaj   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Dynamic rupture of metal sheet subjected to laser irradiation and tangential subsonic airflow

Theoretical and Applied Mechanics Letters, 2018
: To reproduce the premature rupture process of metal sheet subjected to laser irradiation with subsonic airflow, which is an interesting phenomenon observed in the experiments given by Lawrence Livermore National Laboratory, a coupled numerical model ...
Xiaodong Xing, Te Ma, Ruixing Wang, Chenyu Cao, Hongwei Song, Chenguang Huang   +5 more
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Rupture History of the 13th November 2017 Mw 7.3 Iran-Iraq Border Region Earthquake Based on Teleseismic Data

Advances in Civil Engineering, 2019
We have examined the temporal and spatial slip distribution of the 2017 Mw 7.3 Iran-Iraq border region earthquake, utilizing 49 broadband teleseismic P-wave records. Based on the nonnegative least square method and multi-time window, a finite fault model
Deyu Yin, Qifang Liu, Yuexin She, Yun Dong   +3 more
doaj   +1 more source

Comprehensive Assessment of Arterial, Tissue, and Venous Collaterals for Evaluating the Infarct Growth Rate: The Multimodal Collateral Score

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Collaterals are crucial factors that influence the infarct growth rate (IGR). We aimed to determine whether a comprehensive multimodal collateral score (MCS), incorporating collateral assessment at the arterial, tissue, and venous levels, is associated with functional independence and provides incremental prognostic value over ...
Giorgio Busto, Umberto Pensato, Ilaria Casetta, Giorgio U. Marcello, Angelo Barra, Anna Poggesi, Edoardo Carlesi, Sara Mancini, Andrea Ginestroni, Vittorio Miele, Alessandro Padovani, Andrea Morotti, Enrico Fainardi   +12 more
wiley   +1 more source