Results 51 to 60 of about 1,213 (124)

Animal Venom Pharmacological Resources: Exploiting Bioactive Peptides to Target Multi–Drug‐Resistant Bacteria

Biochemistry Research International, Volume 2026, Issue 1, 2026.
Background The escalating rise of multi–drug‐resistant (MDR) bacterial strains significantly threatens global health, creating a “silent pandemic” prompted by natural selection, gene mutation, and horizontal gene transfer. This crisis is worsened by the deficit in the development of new treatments, necessitating the innovative discovery of new potent ...
Rima Jaber, César Mattei, Claudine Accary, Rabih Roufayel, Ziad Abi Khattar, Ziad Fajloun, Yoel A. Klug   +6 more
wiley   +1 more source

Concurrent Acquired Hemophilia A and Lupus Anticoagulant Managed With Emicizumab and Immunosuppression: A Case Report

Case Reports in Hematology, Volume 2026, Issue 1, 2026.
Acquired hemophilia A (AHA) is a rare bleeding disorder that can be accompanied by challenges in diagnosis and management when there is a concurrent lupus anticoagulant. A 72‐year‐old male with no bleeding or thrombotic history presented with new spontaneous hematomas of the extremities and an isolated severely prolonged aPTT.
Julie Williamson, Kristi Smock, Karen Moser, Richard A. King, Ana Antun   +4 more
wiley   +1 more source

Unusual visual loss after snakebite

Journal of Venomous Animals and Toxins including Tropical Diseases, 2010
Snakebites are endemic in some parts of Thailand, being associated with several complications. Ocular disturbances are uncommon, except in cases of corneal or conjunctival injury, when the eye is directly exposed to the snake venom.
N Tungpakorn
doaj   +1 more source

Hydroxyurea‐Associated Wunderlich Syndrome in Triple‐Negative Myelofibrosis: A Case Report and Literature Review

Case Reports in Hematology, Volume 2026, Issue 1, 2026.
Background Wunderlich syndrome (WS) is a spontaneous, nontraumatic intrarenal or perirenal hemorrhage most commonly related to renal neoplasms, vascular disorders, infection, cyst rupture, or anticoagulation. Clinical severity ranges from self‐limited bleeding to hemorrhagic shock.
Veysel Erol, Zeki Güzel, İbrahim Ethem Akgün, Gökhan Ecer, Rounak Dubey   +4 more
wiley   +1 more source

Autoimmune Thrombocytopenia Treated by Low‐Dose Splenic Irradiation Followed by Splenectomy in a Patient With Systemic Lupus Erythematosus

Clinical Case Reports, Volume 13, Issue 12, December 2025.
ABSTRACT Severe autoimmune thrombocytopenia (ATP) in systemic lupus erythematosus (SLE) patients can be life‐threatening when refractory to standard treatments. Low‐dose splenic irradiation (LDSI) can provide temporary platelet recovery before definitive splenectomy.
Ryosuke Hanaoka
wiley   +1 more source

Thrombolytic Therapy for Massive Pulmonary Embolism in an Antiphospholipid Syndrome Patient With Severe Thrombocytopenia: A Case Report

Clinical Case Reports, Volume 13, Issue 11, November 2025.
ABSTRACT Thrombocytopenia (TCP) is a well‐known contraindication for thrombolytic therapy due to the associated risk of bleeding. This report discusses a 34‐year‐old woman presented with massive pulmonary embolism (PE) and severe TCP. She was treated with systemic thrombolysis (ST), and fortunately, a good therapeutic response was achieved without ...
Arman Ahmadzadeh, Samad Nazar Poor, Reza Hamneshin Behbahani, Pegah Soltani, Arian Tavasol, Mehdi Sheibani   +5 more
wiley   +1 more source

An in vivo examination of the differences between rapid cardiovascular collapse and prolonged hypotension induced by snake venom

Scientific Reports, 2019
We investigated the cardiovascular effects of venoms from seven medically important species of snakes: Australian Eastern Brown snake (Pseudonaja textilis), Sri Lankan Russell’s viper (Daboia russelii), Javanese Russell’s viper (D.
Rahini Kakumanu, Barbara K. Kemp-Harper, Anjana Silva, Sanjaya Kuruppu, Geoffrey K. Isbister, Wayne C. Hodgson   +5 more
doaj   +1 more source

IgG and IgM Anti‐Phosphatidylserine/Prothrombin Complex Antibody Detection May Improve Classification Accuracy of Systemic Lupus Erythematosus and Antiphospholipid Antibody Syndrome

ACR Open Rheumatology, Volume 7, Issue 10, October 2025.
Objective Antiphospholipid antibody (aPL) syndrome (APS) classification requires a thrombotic event and detection of lupus anticoagulant (LAC), anticardiolipin antibodies (aCL), or anti–β2‐glycoprotein I (anti‐β2GPI) antibodies on two occasions ≥12 weeks apart. Here, we investigated the utility of anti–phosphatidylserine/prothrombin complex (anti‐PS/PT)
Christina Donath, Sara Kahlown, Liye Suo, Katalin Banki, Andras Perl   +4 more
wiley   +1 more source

Snake Venom Pharmacokinetics and Acute Toxic Outcomes Following Daboia siamensis Envenoming: Experimental and Clinical Correlations

Toxins
An understanding of snake venom pharmacokinetics is essential for determining clinical outcomes of envenoming and developing therapeutic approaches to the treatment of envenoming, especially regarding the timing and optimal dosage of antivenom ...
Sethapong Lertsakulbunlue, Wipapan Khimmaktong, Orawan Khow, Wittawat Chantkran, Jureeporn Noiphrom, Kanyanat Promruangreang, Lawan Chanhome, Janeyuth Chaisakul   +7 more
doaj   +1 more source

Incidence and treatment of snakebites in West Bengal, India

Toxicology Reports, 2019
Objective: Snake envenomation is a major cause of death and disability in the developing countries. In India and neighboring countries, the four venomous snakes of concern include – Indian cobra(Naja naja), Common Krait (Bungarus caeruleus); Russell's ...
Kaushik Mana, Rituparna Ghosh, Kripasindhu Gantait, Kanchan Saha, Poulami Parua, Upasana Chatterjee, Sumana Sarkhel   +6 more
doaj   +1 more source