Results 1 to 10 of about 21,753 (168)

Ruthenium Anticancer Compounds: Challenges and Expectations

CHIMIA, 2007
Two ruthenium compounds, namely [ImH]trans-[RuCl4(Im)(dmso-S)] (NAMI-A, Im = imidazole) and [IndH] trans-[RuCl4(Ind)2] (KP1019, Ind = indazole) have already completed phase I clinical trials as anticancer agents.
Ioannis Bratsos, Stephanie Jedner, Teresa Gianferrara, Enzo Alessio   +3 more
doaj   +5 more sources

Nucleosome acidic patch-targeting binuclear ruthenium compounds induce aberrant chromatin condensation [PDF]

Nature Communications, 2017
Histone H2A–H2B dimers in nucleosomes contain an acidic patch, a highly electronegative cleft. Here, the authors characterize a family of binuclear ruthenium compounds that selectively target the acidic patch, generating intra-nucleosomal H2A-H2B cross ...
Gabriela E. Davey, Zenita Adhireksan, Zhujun Ma, Tina Riedel, Deepti Sharma, Sivaraman Padavattan, Daniela Rhodes, Alexander Ludwig, Sara Sandin, Benjamin S. Murray, Paul J. Dyson, Curt A. Davey   +11 more
doaj   +2 more sources

Pt-Ru Alloy Catalysts with Doped CeO2 Interlayer for Methane Conversion [PDF]

한국정밀공학회지, 2020
The necessity of converting toxic gas has arisen from the usage of perfluorinated compounds (PFCs), volatile organic compounds (VOCs), and hydrocarbon gases in the semiconductor process and laboratories.
Min Jong Kil, Heesung Park, Hyong June Kim, Byung Chan Yang, Jemin Lee, Ye Seul Kim, Hojoong Sun, Cheolwoo Bong, Moon Soo Bak, Jihwan An   +9 more
doaj   +1 more source

The Behavior of Ruthenium in Copper Electrowinning

Metals, 2022
The recycling of material containing precious metals can lead to the entry of ruthenium into the copper electrowinning process, by so far unknown effects. There, ruthenium is oxidized to highly volatile ruthenium tetroxide.
Alexandra Thiere, Hartmut Bombach, Michael Stelter   +2 more
doaj   +1 more source

New Organometallic Ru(II) Compounds with Lonidamine Motif as Antitumor Agents

Pharmaceutics, 2023
The combination of one molecule of organic and metal-based fragments that exhibit antitumor activity is a modern approach in the search for new promising drugs.
Ilya A. Shutkov, Yulia N. Okulova, Dmitrii M. Mazur, Nikolai A. Melnichuk, Denis A. Babkov, Elena V. Sokolova, Alexander A. Spasov, Elena R. Milaeva, Alexey A. Nazarov   +8 more
doaj   +1 more source

Anti-Inflammatory Mechanisms of Novel Synthetic Ruthenium Compounds

Applied Sciences, 2021
Inflammation is the primary biological reaction to induce severe infection or injury in the immune system. Control of different inflammatory cytokines, such as nitric oxide (NO), interleukins (IL), tumor necrosis factor alpha-(TNF-α), noncytokine ...
Thanasekaran Jayakumar, Joen-Rong Sheu, Chih-Wei Hsia, Periyakali Saravana Bhavan, Chao-Chien Chang   +4 more
doaj   +1 more source

Tuning the Cytotoxicity of Bis-Phosphino-Amines Ruthenium(II) Para-Cymene Complexes for Clinical Development in Breast Cancer

Pharmaceutics, 2021
Despite some limitations such as long-term side effects or the potential presence of intrinsic or acquired resistance, platinum compounds are key therapeutic components for the treatment of several solid tumors. To overcome these limitations, maintaining
Elena Domínguez-Jurado, Francisco J. Cimas, José Antonio Castro-Osma, Alberto Juan, Agustín Lara-Sánchez, Antonio Rodríguez-Diéguez, Alexandr Shafir, Alberto Ocaña, Carlos Alonso-Moreno   +8 more
doaj   +1 more source

Mechanochemical synthesis of intermetallic compounds in the system gallium – ruthenium

Chimica Techno Acta, 2021
The interaction of a solid inert metal Ru with liquid active metal Ga during mechanical activation in a high-energy planetary ball mill was studied using the X-ray diffraction and the high resolution scanning electron microscopy with energy dispersive X ...
T. F. Grigoreva, E. A. Pavlov, P. A. Vitiaz, N. Z. Lyakhov   +3 more
doaj   +1 more source

Antioxidant activity of new ruthenium compounds [PDF]

Redox Report, 2005
Many biological properties have been attributed to ruthenium complexes including anti-tumor activity and the attenuation of reperfusion damage and infarct size. In this work, we characterize the antioxidant activity of trans-[RuCl2(nic)4] where nic is 3-pyridinecarboxylic acid and trans-[RuCl2(i-nic)4] where i-nic is 4-pyridinecarboxylic acid by (i ...
Marcos Marques da Silva, Paula, Claus Tröger, Pich, Fabrícia, Petronilho, Lilian Batista, Drei, Martina, Rudnicki, Marcos Roberto, de Oliveira, José Cláudio Fonseca, Moreira, João Antônio Pegas, Henriques, César Vittorio, Franco, Felipe, Dal Pizzol   +9 more
openaire   +2 more sources

Dichloro[N-[(η⁶-phenyl)methyl]-4-(1-(3,5,5,8,8-pentamethyl-5,6,7,8tetrahydronaphthalen-2-yl)vinyl)benzamide](1,3,5-triaza-7-phosphatricyclo [3.3.1.1^3,7]decane-κP⁷)ruthenium

Molbank, 2022
Bexarotene-tethered RuII(arene) compounds with 1,3,5-triaza-7-phosphatricyclo[3.3.1.1]decane (PTA) were prepared as an analog of RAPTA antitumor complexes in order to evaluate their in vitro antiproliferative activity against human cancer cell lines.
Ilya A. Shutkov, Dmitrii M. Mazur, Nataliya E. Borisova, Elena R. Milaeva, Alexey A. Nazarov   +4 more
doaj   +1 more source