Results 21 to 30 of about 21,947 (264)

Half-Sandwich Arene Ruthenium(II) Thiosemicarbazone Complexes: Evaluation of Anticancer Effect on Primary and Metastatic Ovarian Cancer Cell Lines

Frontiers in Pharmacology, 2022
In this study, we describe the synthesis, characterization and antiproliferative activity of three organo-ruthenium(II) half-sandwich complexes [RuCl(η6-p-cym)(N,S-L)]Cl (I, II, and III).
Seminay Guler, Seminay Guler, Hulya Ayar Kayali, Hulya Ayar Kayali, Hulya Ayar Kayali, Egemen Orkun Sadan, Betul Sen, Elif Subasi   +7 more
doaj   +1 more source

Bidentate Donor-Functionalized N-Heterocyclic Carbenes: Valuable Ligands for Ruthenium-Catalyzed Transfer Hydrogenation

Molecules, 2022
Ruthenium complexes are by far the most studied compounds that catalyze hydrogen transfer reactions. In this review, we describe the use in this field of ruthenium complexes bearing bidentate donor-functionalized N-heterocyclic carbene ligands.
Vincent Ritleng, Christophe Michon
doaj   +1 more source

Hydrodeoxygenation of lignin-derived guaiacol using ruthenium‑titanium-oxide aerogel catalysts

Applied Catalysis O: Open
Catalytic hydrodeoxygenation of biomass-derived oxygenates to deoxygenated chemicals and fuels is a major research area, but selective production of aromatic compounds remains challenging, because complete deoxygenation favors formation of saturated ...
Jisong Kang, Shedrack G. Akpe, Yerin Lee, Myung-June Park, Seo-Jung Han, Taejin Kim, Jae-Wook Choi, Chun-Jae Yoo, Hyunjoo Lee, Kyeongsu Kim, Kwang Ho Kim, Chang Soo Kim, Jungkyu Choi, Kwang Ho Song, Kangtaek Lee, Hyung Chul Ham, Jeong-Myeong Ha   +16 more
doaj   +1 more source

Ruthenium: Past and Present

Тонкие химические технологии, 2019
This article provides information on one of the most interesting elements in the D.I. Mendeleev Periodic Table - ruthenium, discovered 175 years ago by the outstanding Russian chemist Karl Karlovich Klaus.
T. M. Buslaeva, E. V. Fesik, N. A. Khan
doaj   +1 more source

Anticancer Half-Sandwich Rhodium(III) Complexes

Inorganics, 2021
Platinum-based anticancer drugs are most likely the most successful group of bioinorganic compounds. Their apparent disadvantages have led to the development of anticancer compounds of other noble metals, resulting in several ruthenium-based drugs which ...
Klaudia Máliková, Lukáš Masaryk, Pavel Štarha   +2 more
doaj   +1 more source

The Role of the Second Coordination Sphere in the Biological Activity of Arene Ruthenium Metalla-Assemblies

Frontiers in Chemistry, 2018
For nearly 15 years, the biological and biomedical applications of arene ruthenium metalla-assemblies have flourished. Today, the synthetic strategies to generate arene ruthenium assemblies are well-established, and these compounds offer tremendous ...
Bruno Therrien
doaj   +1 more source

Conjugates Containing Two and Three Trithiolato-Bridged Dinuclear Ruthenium(II)-Arene Units as In Vitro Antiparasitic and Anticancer Agents

Pharmaceuticals, 2020
The synthesis, characterization, and in vitro antiparasitic and anticancer activity evaluation of new conjugates containing two and three dinuclear trithiolato-bridged ruthenium(II)-arene units are presented.
Valentin Studer, Nicoleta Anghel, Oksana Desiatkina, Timo Felder, Ghalia Boubaker, Yosra Amdouni, Jessica Ramseier, Martin Hungerbühler, Christoph Kempf, Johannes Thomas Heverhagen, Andrew Hemphill, Nico Ruprecht, Julien Furrer, Emilia Păunescu   +13 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Recent Trends in the Design of Ruthenium Homometallic Polynuclear Complexes with Bioactive Ligands for Cancer Treatment

Inorganics
Significant efforts have been devoted to discovering novel metal-based complexes with better cytotoxicity and specificity to tumor cells. Within the range of complexes studied for cytotoxic activity, Ru complexes have gained significant attention as one ...
Irena Kostova
doaj   +1 more source

Ruthenium(II)-diimin-Komplexe: Photosensibilisatoren mit einzigartigen Eigenschaften

CHIMIA, 1990
Some Ruthenium(II)-diimine complexes have remarkable properties, which allow them to act as photosensitizers for the conversion of 'photon energy' into other utilizable energy forms.
Peter Belser
doaj   +1 more source