Ruthenium(II) Arene Compounds as Versatile Anticancer Agents
CHIMIA, 2009 Ruthenium-based compounds are an attractive alternative to clinically used platinum drugs due to several features including a wide range of accessible oxidation states, varied synthetic chemistry and typically lower general toxicities.
Anna Renfrew
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Cyclohexene Hydrocarbomethoxylation Catalysed By Ruthenium Compounds
, 2016 This paper presents a catalytic activity of ruthenium (III) compounds in the model reaction of cyclohexene hydrocarbomethoxylation. The objective of the work was contained in the determination of the most active ruthenium catalyst of this reaction. The kinetic method was used as the main method of investigation. The gas–liquid chromatography method was
Sevostyanova N., Batashev S.
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Some iodo-compounds of ruthenium.
, 1964 The work described in this thesis is concerned with an investigation into the preparation and properties of ruthenium nitrosyl di-iodide and ruthenium tri-iodide. The preparation of ruthenium nitrosyl di-iodide Ru(NO)I[2], by treating ruthenium dicarbonyl di-iodide Ru(CO)[2]I[2], with nitric oxide is described, and its structure is discussed.
Laye, Peter George.
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New Nucleic Base-tethered Trithiolato-bridged Dinuclear Ruthenium(II)-Arene Compounds: Synthesis and Antiparasitic Activity [PDF]
, 2022 Aiming to generate novel compounds with improved antitoxoplama activity by exploiting the parasite auxotrophies, a library of nucleic base-tethered trithiolato-bridged dinuclear ruthenium(II)-arene conjugates - was synthesized and evaluated.
Emila, Păunescu +7 more
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A Combination of Ruthenium Complexes and Photosensitizers to Treat Colorectal Cancer
Inorganics, 2023 Treatment regimens are regularly evolving alongside novel therapies and drugs. Such evolution is necessary to circumvent resistance mechanisms and to give patients the best possible health care.
Jacquie Massoud +9 more
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Rational Design of Organo-Ruthenium Anticancer Compounds
CHIMIA, 2005 Organometallic ruthenium(II)-arene complexes are currently attracting increasing interest as anticancer compounds with the potential to overcome drawbacks of traditional drugs like cisplatin with respect to resistance, selectivity, and toxicity.
Christian Gossens +2 more
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Synthesis, spectral, dna binding and cleavage properties of ruthenium(II) Schiff base complexes containing PPh3/AsPh3 as co-ligands [PDF]
Journal of the Serbian Chemical Society, 2014 A dihydroxybenzaldehyde Schiff base ligands (L1-L3) and its ruthenium(II) complexes, have been synthesized and characterized on the basis of elemental analysis, 1H, 13C, 31P NMR, mass spectra, UV-vis and IR spectra.
Sathiyaraj Subbaiyan +2 more
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Biological Activities of Ruthenium NHC Complexes: An Update
Antibiotics, 2023 Ruthenium N-heterocyclic carbene (NHC) complexes have unique physico-chemical properties as catalysts and a huge potential in medicinal chemistry and pharmacology, exhibiting a variety of notable biological activities.
Alessia Catalano +6 more
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Unusual DNA binding modes for metal anticancer complexes [PDF]
, 2009 DNA is believed to be the primary target for many metal-based drugs. For example, platinum-based anticancer drugs can form specific lesions on DNA that induce apoptosis.
Pizarro, Ana M., Sadler, P. J.
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Somatostatin subtype-2 receptor-targeted metal-based anticancer complexes [PDF]
, 2012 Conjugates of a dicarba analogue of octreotide, a potent somatostatin agonist whose receptors are overexpressed on tumor cells, with [PtCl 2(dap)] (dap = 1-(carboxylic acid)-1,2-diaminoethane) (3), [(η 6-bip)Os(4-CO 2-pico)Cl] (bip = biphenyl, pico ...
González, Carlos A. +24 more
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