Results 101 to 110 of about 21,947 (264)

Bias‐Engineered Synthetic Antiferromagnets Hosting Sub‐20 nm Zero‐Field Skyrmions at Room Temperature

open access: yesAdvanced Science, EarlyView.
A fully compensated synthetic antiferromagnet (SAF) multilayer exhibits a uniform state at zero field, without skyrmions. We use a SAF bias system to provide RKKY‐mediated exchange bias to the SAF multilayer, promoting zero‐field skyrmion stabilization and polarity control.
Emily Darwin   +5 more
wiley   +1 more source

Necroptosis induced by ruthenium (II) complexes as mitochondrial disruptors

open access: yesCell Death Discovery
Inducing necroptosis in cancer cells has emerged as an effective strategy to overcome drug resistance. However, while organic small molecules have been extensively studied for this purpose, metal-based compounds have received relatively little attention ...
Joana Gonçalves   +12 more
doaj   +1 more source

Strain‐Preserving Transfer of Freestanding Oxide Membranes for Tunable Magnetic Anisotropy

open access: yesAdvanced Science, EarlyView.
An epoxy‐assisted exfoliation and transfer strategy circumvents the trade‐off between structural flexibility and strain tunability in freestanding oxide membranes. Epitaxial strain is effectively preserved, enabling versatile and robust control of magnetic anisotropy without sacrificing flexibility.
Jinfeng Zhang   +13 more
wiley   +1 more source

Targeting KDM3B Elicits Anti‐tumor Immunity by Alleviating SHP1–mediated STING Suppression in Triple–Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
P3FI–90 treatment targets KDM3B, reshapes the epigenetic landscape, and suppresses SHP1 expression, thereby activating STING–TBK1–IRF3–type I IFN signaling pathway. Consequently, CD8+ T cells are recruited to the tumor site and activated to produce IFN–γ and GZMB, leading to the killing of TNBC cells.
Xiaolong Wang   +8 more
wiley   +1 more source

Magnetically Boosted Water‐Splitting Performance in Metallic Glasses

open access: yesAdvanced Science, EarlyView.
A strategy for boosting water electrolysis efficiency using ultralow magnetic fields on soft‐magnetic MG wires is reported. Ni40Fe40P20 metallic glass exhibits superior overall water‐splitting performance (1.51 V @ 1000 mA cm−2) at 100 Oe, enabled by spin polarization in periodic surface magnetic domains to enhance orbital hybridization and net spin ...
Chaoqun Pei   +9 more
wiley   +1 more source

Construction of Sabatier Volcanoes for CO2 Hydrogenation to C1‐2 Oxygenates Using Data‐Efficient Machine Learning

open access: yesAdvanced Science, EarlyView.
A new data‐efficient framework combining DFT calculations, a neural network model, and automated graph analysis of catalytic reaction networks is proposed and applied to CO2 hydrogenation on transition metal nanoparticles. The analysis shows how efficient C2 oxygenate production requires a balance between CHx formation, C–C coupling, protonation, and ...
Mikhail V. Polynski, Sergey M. Kozlov
wiley   +1 more source

Reconstruction of Nickel Chalcogenide Induced Ruthenium Nanoparticles Embedding for Oxygen Evolution: Mechanism Switching Enables Enhanced Catalytic Activity

open access: yesAdvanced Science, EarlyView.
Ru nanoparticles supported nickel chalcogens (Ru/NiX, X = S, Se), which enable fast electrooxidation to form an adaptively Ru embedding structure, featured by the compressed Ru─O─Ni bridge bonds at the Ru/NiOOH interface. On the one hand, Ru nanoparticles have a high affinity for capturing the OH−, consequently increasing the *O radical coverage.
Yuewen Wu   +10 more
wiley   +1 more source

Targeting DNGR‐1 with Fangchinoline Elevates Dendritic Cell Antigen Cross‐Presentation‐Mediated Antitumor Immunity in Melanoma

open access: yesAdvanced Science, EarlyView.
Fangchinoline is identified as a small‐molecule DNGR‐1 modulator that enhances dendritic‐cell cross‐presentation of tumor antigens. By engaging DNGR‐1 and activating Syk–Nox2 signaling, it promotes phagosomal ROS, antigen escape, MHC‐I presentation, and CD8+ T‐cell priming, thereby strengthening antitumor immunity and sensitizing tumors to PD‐1 ...
Yuan Liao   +19 more
wiley   +1 more source

A High‐Current‐Tolerant Multimetallic Phosphide Electrode for Alkaline Water Electrolysis Toward Industrial Conditions

open access: yesAdvanced Science, EarlyView.
A phosphide‐modified multimetallic HER electrode achieves industrial‐level performance with minimal noble‐metal content. It delivers 1.7 A cm−2 at 2.0 V in 6 M KOH at 70°C and operates stably for over 200 h at 500 mA cm−2. Phosphorus tuning of the electronic structure optimizes hydrogen adsorption, offering a durable, high‐rate pathway for alkaline ...
Yang Li   +5 more
wiley   +1 more source

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