Results 41 to 50 of about 51,241 (200)

Molecular evolution of ultraspiracle protein (USP/RXR) in insects. [PDF]

PLoS ONE, 2011
Ultraspiracle protein/retinoid X receptor (USP/RXR) is a nuclear receptor and transcription factor which is an essential component of a heterodimeric receptor complex with the ecdysone receptor (EcR).
Ekaterina F Hult, Stephen S Tobe, Belinda S W Chang   +2 more
doaj   +1 more source

A Retinoid X Receptor Agonist Directed to the Large Intestine Ameliorates T-Cell-Mediated Colitis in Mice

Frontiers in Pharmacology, 2021
Retinoid X receptor (RXR) is a nuclear receptor that heterodimerizes with several nuclear receptors, integrating ligand-mediated signals across the heterodimers.
Ryohtaroh Matsumoto, Daisuke Takahashi, Masaki Watanabe, Shunsuke Nakatani, Yuta Takamura, Yuji Kurosaki, Hiroki Kakuta, Koji Hase, Koji Hase   +8 more
doaj   +1 more source

TLR3 Deficiency Leads to a Dysregulation in the Global Gene-Expression Profile in Murine Oviduct Epithelial Cells Infected with Chlamydia muridarum [PDF]

, 2019
OBJECTIVE Describe the implementation and effects of Mobile Acute Care for Elders (MACE) consultation at a Veterans Affairs Medical Center (VAMC). DESIGN Retrospective cohort analysis.
Derbigny, Wilbert A, Kumar, Ramesh
core   +2 more sources

DHA (omega-3 fatty acid) increases the action of brain-derived neurotrophic factor (BDNF)

Oilseeds and fats, crops and lipids
Neurons have high energy needs, requiring a continuous supply of glucose from the blood. Tight regulation of glucose metabolism in response to stimuli is essential for brain physiology.
Majou Didier, Dermenghem Anne-Lise
doaj   +1 more source

Combined LXR and RXR Agonist Therapy Increases ABCA1 Protein Expression and Enhances ApoAI-Mediated Cholesterol Efflux in Cultured Endothelial Cells

Metabolites, 2021
Endothelial ABCA1 expression protects against atherosclerosis and this atheroprotective effect is partially attributed to enhancing apoAI-mediated cholesterol efflux.
Kun Huang, Hanjoong Jo, Jing Echesabal-Chen, Alexis Stamatikos   +3 more
doaj   +1 more source

Exposure to tributyltin chloride induces penis and vas deferens development and increases RXR expression in females of the purple snail (Plicopurpura pansa) [PDF]

Invertebrate Survival Journal, 2014
Tributyltin (TBT) and its derivatives are widely used as antifouling paints for ships, resulting in their being released into the marine environment.
D Domínguez-Ojeda, A E Rojas-García, M L Robledo-Marenco, B S Barrón-Vivanco, I M Medina-Díaz   +4 more
doaj   +1 more source

Towards a unified molecular mechanism for ligand-dependent activation of NR4A-RXR heterodimers

eLife
A subset of nuclear receptors (NRs) function as permissive heterodimers with retinoid X receptor (RXR), defined by transcriptional activation in response to RXR agonist ligands.
Xiaoyu Yu, Yuanjun He, Thedore M Kamenecka, Douglas J Kojetin   +3 more
doaj   +1 more source

Eigenvalue statistics for product complex Wishart matrices

, 2014
The eigenvalue statistics for complex $N \times N$ Wishart matrices $X_{r,s}^\dagger X_{r,s}$, where $ X_{r,s}$ is equal to the product of $r$ complex Gaussian matrices, and the inverse of $s$ complex Gaussian matrices, are considered.
Forrester, Peter J.
core   +1 more source

The Transition Function of $G_2$ over $S^6$ [PDF]

, 2019
We obtain explicit formulas for the trivialization functions of the ${\rm SU}(3)$ principal bundle $G_2 \to S^6$ over two affine charts. We also calculate the explicit transition function of this fibration over the equator of the six-sphere.
Gyenge, Ádám
core   +3 more sources

PPARs/RXRs in Cardiovascular Physiology and Disease [PDF]

PPAR Research, 2008
The PPAR family of nuclear receptor transcription factors are important regulators of cardiovascular function and metabolism. Because of this, PPARs are potentially interesting pharmacologic targets for treating cardiometabolic disease. The reviews in this series discuss the regulatory functions of PPARs in maintaining metabolic and physiologic ...
Brian N. Finck, Giulia Chinetti, Bart Staels   +2 more
openaire   +3 more sources