Results 171 to 180 of about 49,122 (245)

UNC45B Reduction With Aging: A Myofiber‐Intrinsic Promoting Factor for Sarcopenia

Aging Cell, Volume 25, Issue 5, May 2026.
Aging reduces Unc45b expression in fast‐twitch muscle, concomitant with reduction in muscle contractile capacity and muscle mass in mice. Unc45b deficiency initially reduces depolarization‐induced force, followed by a decline in fast‐twitch muscle mass in adult mice.
Taiga Mishima, Taiga Nagamune, Saori Tada, Daiki Watanabe, Nao Tokuda, Takashi Yamada, Akiko Hashimoto‐Hachiya, Sayaka Higo‐Yamamoto, Kohei Kido, Noriyuki Nagaoka, Aoi Ikedo, Yuuki Imai, Ryo Fujita, Seiya Mizuno, Satoru Takahashi, Katsutaka Oishi, Satoru Ato, Riki Ogasawara   +17 more
wiley   +1 more source

Cells and ionic conductances contributing to spontaneous activity in bladder and urethral smooth muscle

The Journal of Physiology, Volume 604, Issue 9, Page 3611-3632, 1 May 2026.
Abstract figure legend Cells and conductances contributing to spontaneous activity in the lower urinary tract. Bladder and urethra exhibit spontaneous contractions at both cellular and tissue levels. Both detrusor and urethral smooth muscle cells display activity that is regular and rhythmic.
Bernard T. Drumm, Neha Gupta, Alexandru Mircea, Caoimhin S. Griffin   +3 more
wiley   +1 more source

Pacemaking in the heart: a redundant and robust system of mutually entrained oscillators driving cardiac automaticity

The Journal of Physiology, Volume 604, Issue 9, Page 3504-3512, 1 May 2026.
Abstract figure legend Cardiac pacemaking: the redundant and robust organ‐to‐subcellular system driving the spontaneous electrical activity responsible for regular, rhythmic excitation of the heart. Abstract The heart is an electrically controlled, mechanical pump that provides a constant supply of blood to the body.
Eilidh A. MacDonald, T. Alexander Quinn
wiley   +1 more source

Ryanodine receptor 2 mutations in catecholaminergic polymorphic ventricular tachycardia: From molecular mechanisms to precision medicine. [PDF]

World J Cardiol
Sharma V.
europepmc   +1 more source

Intracellular calcium oscillations [PDF]

, 2000
Coxhead, Peter D.
core  

Ryanodine receptor 2-mediated calcium leak is associated with increased glyoxalase I in the aging brain. [PDF]

JCI Insight
Woo E, Datta D, Bathla S, Beatty H, Caglayan P, Albizu AK, Lam TT, Kanyo J, Joyce MK, Leslie S, Uchendu S, DeLong J, Guan QS, Li J, Abramson E, Herman AL, Cooper D, Licznerski P, Horvath TL, Jonas EA, Nairn AC, Arnsten AF, Sansing LH.   +22 more
europepmc   +1 more source

Clinical and Functional Characterization of Ryanodine Receptor 2 Variants Implicated in Calcium-Release Deficiency Syndrome.

JAMA Cardiol, 2022
Roston TM, Wei J, Guo W, Li Y, Zhong X, Wang R, Estillore JP, Peltenburg PJ, Noguer FRI, Till J, Eckhardt LL, Orland KM, Hamilton R, LaPage MJ, Krahn AD, Tadros R, Vinocur JM, Kallas D, Franciosi S, Roberts JD, Wilde AAM, Jensen HK, Sanatani S, Chen SRW.   +23 more
europepmc   +1 more source

Loss of Ryanodine Receptor 2 impairs neuronal activity-dependent remodeling of dendritic spines and triggers compensatory neuronal hyperexcitability. [PDF]

Cell Death Differ, 2020
Bertan F, Wischhof L, Sosulina L, Mittag M, Dalügge D, Fornarelli A, Gardoni F, Marcello E, Di Luca M, Fuhrmann M, Remy S, Bano D, Nicotera P.   +12 more
europepmc   +1 more source

Ex Vivo Single-molecule Analysis of Ryanodine Receptor 2 Assembly in Cardiac and Neuronal Tissue. [PDF]

J Vis Exp
Yin Q, Richards CI.
europepmc   +1 more source

Potential contribution of ryanodine receptor 2 upregulation to cGMP/PKG signaling-induced cone degeneration in cyclic nucleotide-gated channel deficiency. [PDF]

FASEB J, 2020
Yang F, Ma H, Butler MR, Ding XQ.
europepmc   +1 more source