Results 41 to 50 of about 3,085,356 (235)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
, 1990 Le problème de la Séquence Globale Minimale, connue dans la littérature sous le nom de "Plus Courte Super-séquence Commune", est un problème NP-complet. On le rencontre dans plusieurs domaines tels que la linguistique computationnelle et la lexicographie.
Souilah, Abdelghani
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Une séquence photographique de la mission Dakar-Djibouti : les funérailles d’Ayaléo
Afriques, 2012 The French Dakar-Djibouti mission took pictures of “Ayaléo’s burial” from start to finish, a “sequence” of about thirty photographs with a unity of subject, time and place. This set presents the funeral of the mission’s mule-driver, held near the city of
Estelle Sohier
doaj +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Les séquences métalinguistiques dans l’interaction exolingue en français langue étrangère : le cas de l’hétéro-régulation [PDF]
Synergies Chine, 2019 L’interaction exolingue se différencie de l’interaction endolingue dans la mesure où il existe des divergences considérables entre les répertoires linguistiques respectifs des interlocuteurs. Pour qu’une communication fonctionne, les participants doivent
XU Yiru, LEE Hsin-i
doaj
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
, 1974 Palmer F.R. Ordre et Séquence. In: Langages, 8ᵉ année, n°34, 1974. La linguistique en Grande-Bretagne dans les années soixante, sous la direction de Jacques Durand et David Robinson. pp.
Palmer, Frank Robert
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FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source