Results 121 to 130 of about 147,345 (227)
, 2011 L’émergence du virus de la Bluetongue sérotype 8 (BTV-8) en Europe de nord en 2006 a causé des pertes économiques enélevages bovins. Une vaccination a été mise en place en France sans évaluation ex ante du ratio bénéfice/risque.
Nusinovici, Simon
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Interactions moléculaires entre l'adénovirus entérique de sérotype 41 et la cellule hôte
, 2002 L'adénovirus de sérotype 41 (Ad41) présente plusieurs particularités qui le différencient des autres adénovirus humains, telles que son tropisme ciblé pour le tractus digestif et la présence de deux protéines "fibres" de différentes longueurs, une courte
CHROBOCZEK, Jadwiga, FAVIER, Anne-Laure
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Biotechnology and Bioengineering, EarlyView.Lifecycle perspective on cell and gene therapy manufacturing challenges and enabling GMP solutions. ABSTRACT Cell and gene therapies (CGTs) are revolutionizing modern medicine; however, making these advanced medicines scalable and readily available to commercial manufacturers worldwide is a major challenge. The number of approved CGT products continues
Rajath Samaga +2 more
wiley +1 more source
Biotechnology and Bioengineering, EarlyView.ABSTRACT Vaccines and gene therapies require efficient delivery of genetic material to host cells. Viral vectors leverage viruses' ability to enter host cells to achieve this. Following the SARS‐CoV‐2 vaccine and novel gene therapies that utilize adenovirus vectors, there has been an increase in the demand for large‐scale production of vectors.
Betsy Widdicombe +7 more
wiley +1 more source
Biotechnology and Bioengineering, EarlyView.ABSTRACT Adeno‐associated viruses (AAVs) are the leading vectors for in vivo gene therapy, fueling a growing demand for scalable and robust biomanufacturing processes. Yet, the impact of cell lysis conditions on the performance of midstream and downstream unit operations across serotypes remains poorly characterized.
Arianna Minzoni +20 more
wiley +1 more source
Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality
BMEMat, EarlyView.Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim +9 more
wiley +1 more source
Demonstration of nanofiltration‐based virus safety for AAV manufacturing using model viruses
Biotechnology Progress, EarlyView.Abstract Virus safety for biopharmaceutical products has been a well‐established concern for several decades. While various virus reduction steps have been identified and implemented for traditional plasma‐derived and monoclonal antibody products, there are various challenges to achieving the same virus safety in emerging gene therapy products.
Brian Buesing +2 more
wiley +1 more source
International audienceUn arbovirus est un virus transmis aux vertébrés par des arthropodes hématophages (insectes/tiques). La fièvre catarrhale ovine est une arbovirose causée par le Bluetongue virus (BTV), transmis par les moucherons-piqueurs ...
Monsion, Baptiste +3 more
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Scientific ReportsNon-vaccine-serotypes (non-VT) pose a challenge to reducing invasive pneumococcal disease (IPD). Since 2023, serotype 38 IPD has increased in Denmark promoting investigation of this serotype’s characteristics.
Christel Baagø Schjørring +6 more
doaj +1 more source
METHODS FOR DETECTING C. CANIMORSUS CAPSULAR SEROTYPES IN A SAMPLE
, 2018 La présente invention concerne des procédés d'identification de C. canimorsus dans un échantillon comme l'un du sérotype A, du sérotype B, du sérotype C, du sérotype D ou du sérotype E, des paires d'amorces d'amplification, des ensembles de paires d ...
Cornelis, Guy +2 more
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