Results 131 to 140 of about 147,345 (227)

High‐throughput development and scale‐up of recombinant adeno‐associated virus 5 anion‐exchange chromatography for high‐purity capsid separation

open access: yesBiotechnology Progress, EarlyView.
High‐throughput anion‐exchange chromatography process development enables scalable purification of high‐purity recombinant adeno‐associated virus capsids. Abstract Recombinant adeno‐associated virus (rAAV) production commonly yields a high proportion of empty and partially filled capsids, necessitating downstream purification to enrich full capsids ...
Kevin Vera   +8 more
wiley   +1 more source

Rethinking Delivery Timing in Prenatally Diagnosed Spinal Muscular Atrophy: A Case Report With 2‐Year Follow‐Up

open access: yesAnnals of the Child Neurology Society, EarlyView.
ABSTRACT Objective We describe the clinical course and outcome of a prenatally diagnosed infant with spinal muscular atrophy (SMA) treated immediately after early‐term birth and highlight considerations regarding delivery timing and neonatal management. Methods This male infant had a family history of SMA type 1A.
Emilie Groulx‐Boivin   +8 more
wiley   +1 more source

Antibody responses against foot-and-mouth disease vaccine differ between the sexes in cattle [PDF]

open access: yesEurasian Journal of Veterinary Sciences
Aim: The aim of this study was to investigate the effects of sex on the humoral immune response induced in cattle by vaccination against foot-and-mouth disease virus (FMVD).
Murat Şevik
doaj  

Surveillance épidémiologique des infections invasives à Haemophilus influenzae – 2024

open access: yes
Messages-clés Les infections invasives à Haemophilus influenzae de type b (Hib) sont en nette régression depuis l’introduction de la vaccination anti-Hib généralisée en 1993.
H. Theeten   +7 more
core  

Adeno‐associated virus‐mediated restoration of NaV1.1 in targeted brain regions ameliorates epilepsy in symptomatic Dravet syndrome mice

open access: yesEpilepsia, EarlyView.
Abstract Objective Dravet syndrome (DS) is a developmental and epileptic encephalopathy primarily caused by haploinsufficiency of the SCN1A gene, which encodes the alpha subunit of NaV1.1 voltage‐gated sodium channel. The disease manifests with febrile and spontaneous seizures, developmental delay, cognitive impairment, and increased risk of sudden ...
Martina Mainardi   +4 more
wiley   +1 more source

Phytochemical Investigation and In Vitro Assessment of Antioxidant, Anti‐Inflammatory and Immunomodulatory Properties of Melia azedarach Linn. Extract in Chicken Lymphocyte Model

open access: yesFlavour and Fragrance Journal, EarlyView.
Phytochemistry and biopotential of Melia azedarach Linn. ABSTRACT Melia azedarach Linn. (chinaberry), a medicinal plant native to tropical Asia, is a rich source of diverse bioactive compounds with reported pharmacological activities and promising therapeutic potential.
Priya Chand   +3 more
wiley   +1 more source

Illuminating point‐of‐care diagnostics with aggregation‐induced emission biosensors

open access: yesFlexMat, EarlyView.
This review highlights the application of aggregation‐induced emission luminogens (AIEgens) in point‐of‐care (POC) diagnostics for disease biomarker detection. It systematically examines a range of biosensing platforms, including lateral flow immunoassays, microfluidic chips, and electrochemiluminescence sensors, alongside their utility in detecting ...
Danni Hu   +3 more
wiley   +1 more source

An Overview of Foodborne Risks in Afghanistan

open access: yesFood Safety and Health, EarlyView.
ABSTRACT Foodborne diseases represent a serious yet underrecognized public health burden in Afghanistan, a country shaped by decades of conflict, weak infrastructure, and limited regulatory capacity. This article provides a comprehensive overview of major foodborne risks in the country, including microbiological hazards, chemical contaminants, and ...
Mohammad Aman Ahmadzai   +2 more
wiley   +1 more source

Vaccination contre la FCO en France et en Europe

open access: yes
La vaccination contre la Fièvre Catarrhale Ovine (FCO) est un défi à chaque fois qu’un nouveau sérotype émerge, car il n’existe que peu, voire pas de protection croisée d’un sérotype à un autre, du fait d’une très forte variabilité génétique du virus ...
Pierre Bessière
core   +1 more source

La fièvre catarrhale ovine ou bluetongue

open access: yes, 2006
Au milieu de l'été 2006, de façon inattendue, la fièvre catarrhale ovine a émergé aux Pays-Bas, en Belgique, en Allemagne ainsi que sur la frontière nord de la France.
Bounaadja, Lotfi   +7 more
core  

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