Results 1 to 10 of about 2,274 (114)

Characterizing circadian rest-activity rhythm patterns across Alzheimer's disease continuum in Down syndrome. [PDF]

Alzheimers Dement
Abstract INTRODUCTION Sleep and circadian rest–activity rhythm (RAR) disruption may bidirectionally relate to Alzheimer's disease (AD). Down syndrome (DS), the most common genetic cause of AD, presents sleep disorders, yet RAR patterns across the DS‐associated AD continuum remain uncharacterized. METHODS We analyzed 7‐day wrist actigraphy in 140 adults
Giménez S, Vaqué-Alcázar L, Clos S, Benejam B, Carmona-Iragui M, Maure-Blesa L, Videla L, Zhu N, Altuna M, Arranz J, Barroeta I, Rodríguez-Baz Í, Bejanin A, Bueno A, Fernandez S, Del Hoyo Soriano L, Pertierra L, Alcolea D, Miller B, Grinberg LT, Ruiz J, Lisgaras CP, Wu HT, Lleó A, Osorio RS, Blessing EM, Fortea J.   +26 more
europepmc   +2 more sources

Peak width of skeletonized mean diffusivity reveals early and multifactorial white matter injury across sporadic and Down syndrome-associated Alzheimer's disease. [PDF]

Alzheimers Dement
Abstract INTRODUCTION This study investigates the evolution with disease progression and pathological correlates of peak width of skeletonized mean diffusivity (PSMD), a sensitive diffusion magnetic resonance imaging (MRI) marker of microvascular white matter (WM) injury, in sporadic Alzheimer's disease (sAD) and Down syndrome (DS)–associated AD (DSAD).
Morcillo-Nieto AO, Franquesa-Mullerat M, Zsadanyi SE, Arriola-Infante JE, Vaqué-Alcázar L, Rozalem-Aranha M, Parra JA, Zhao Z, Arranz J, Rodríguez-Baz Í, Maure-Blesa L, Videla L, Barroeta I, Del Hoyo Soriano L, Benejam B, Fernández S, Sanjuan Hernandez A, Pertierra L, Giménez S, Santos-Santos M, Dols-Icardo O, Illán-Gala I, Alcolea D, Belbin O, Lleó A, Carmona-Iragui M, Fortea J, Bejanin A.   +27 more
europepmc   +2 more sources

Los profesionales de Atención Temprana frente al Covid-19: autopercepción competencial de los profesionales en la teleintervención

Siglo Cero, 2021
La situación de emergencia sanitaria, SARS-Cov-19, declarada por la Organización Mundial de la Salud aboca a los Centros de Atención Temprana a trasformar el rol del profesional para poder continuar con el buen funcionamiento del servicio.
Elena López-Riobóo Moreno, Patricia Páramo Rodriguez, Joanne Mampaso Desbrow   +2 more
doaj   +1 more source

¿Qué saben de pubertad, relaciones de pareja y reproducción, un grupo de jóvenes chilenos con Síndrome de Down?

Siglo Cero, 2022
Introducción: vivir la sexualidad y afectividad de forma plena es fundamental en todo ser humano; sin embargo, las personas con síndrome de Down (SD) tienen escasas instancias de educación sexual y pocos espacios de socialización para experimentarla ...
Macarena Palomer Music, Bárbara Berger Correa, Víctor Romero Rojas, Macaren Lizama   +3 more
doaj   +1 more source

European guidelines from the EHTG and ESCP for Lynch syndrome: an updated third edition of the Mallorca guidelines based on gene and gender

BJS (British Journal of Surgery), EarlyView., 2020
Recommendations for clinical and molecular identification of LS, surgical and endoscopic management of LS‐associated colorectal cancer and preventive measures for cancer were produced. The emphasis was on surgical and gastroenterological aspects of the cancer spectrum.
T. T. Seppälä, A. Latchford, I. Negoi, A. Sampaio Soares, R. Jimenez‐Rodriguez, L. Sánchez‐Guillén, D. G. Evans, N. Ryan, E. J. Crosbie, M. Dominguez‐Valentin, J. Burn, M. Kloor, M. von Knebel Doeberitz, F. J. B. van Duijnhoven, P. Quirke, J. R. Sampson, P. Møller, G. Möslein, on behalf of the European Hereditary Tumour Group (EHTG) and European Society of Coloproctology (ESCP)   +18 more
wiley   +1 more source

Neural correlates of episodic memory in adults with Down syndrome and Alzheimer’s disease

Alzheimer’s Research & Therapy, 2022
Background Adults with Down syndrome are at an ultra-high risk of developing early-onset Alzheimer’s disease. Episodic memory deficits are one of the earliest signs of the disease, but their association with regional brain atrophy in the population with ...
Bessy Benejam, Mateus Rozalem Aranha, Laura Videla, Concepción Padilla, Silvia Valldeneu, Susana Fernández, Miren Altuna, Maria Carmona-Iragui, Isabel Barroeta, Maria Florencia Iulita, Víctor Montal, Jordi Pegueroles, Alexandre Bejanin, Sandra Giménez, Sofía González-Ortiz, Sebastián Videla, David Bartrés-Faz, Daniel Alcolea, Rafael Blesa, Alberto Lleó, Juan Fortea   +20 more
doaj   +1 more source

Variables demográficas y psicosociales que modulan el riesgo de suicidio en adolescentes

INFAD, 2015
Se presentan  distintas cuestiones conceptuales sobre el suicidio en adolescentes, y se plantean los factores de riesgo y protección que están relacionados con el comportamiento suicida.
David Sánchez-Teruel, María Auxiliadora Robles-Bello   +1 more
doaj   +1 more source

La "creatividad integrada" desde el análisis de experiencias artísticas con personas con capacidades diversas en espacios académicos

Revista Complutense de Educación, 2017
El presente artículo surge de las actividades creativas que en los últimos años hemos venido desarrollando con personas con síndrome de Down y estudiantes de la Universidad de Murcia en ámbitos académicos, desde los que hemos ido conformando un espacio ...
Eva Santos Sánchez-Guzmán, Eva Cristina Mesas Escobar   +1 more
doaj   +1 more source

Serological investigation of vaccine-induced antibodies for measles, rubella, and yellow fever viruses in children vertically exposed to Zika virus or with down syndrome

Frontiers in Pediatrics, 2023
BackgroundVaccination schedules, as well as their effectiveness and contraindications, need to be evaluated regularly, especially in specific situations.
Débora Familiar-Macedo, Helver Gonçalves Dias, Fabiana Rabe Carvalho, Alex Pauvolid-Corrêa, Mayara Neto da Silveira, Mariana Cavalcante de Oliveira, Rita de Cássia Ferreira Gonçalves, Renata Artimos de Oliveira Vianna, Claudete Aparecida Araujo Cardoso, Claudete Aparecida Araujo Cardoso, Raquel Tavares Boy da Silva, Anna Paula Baumblatt, Luzia Maria de-Oliveira-Pinto   +12 more
doaj   +1 more source

Associação entre cardiopatias congênitas e infeções graves em crianças com síndrome de Down

Revista Portuguesa de Cardiologia, 2014
Resumo: Fundamento: Defeitos cardíacos congênitos (DCC) têm alta prevalência em pacientes com síndrome de Down (SD). Além disso, crianças com SD que possuem DCC são mais suscetíveis às infecções pulmonares do que aqueles que não possuem cardiopatia ...
Paula Foresti Faria, Juliana Augusta Zeglin Nicolau, Marina Zaponi Melek, Nanci de Santa Palmieri de Oliveira, Beatriz Elizabeth Bagatin Veleda Bermudez, Renato Mitsunori Nisihara   +5 more
doaj   +1 more source