Results 11 to 20 of about 2,368 (115)

Changes in serum β-synuclein precede blood biomarkers of Alzheimer pathology in Down syndrome. [PDF]

Alzheimers Dement
Abstract INTRODUCTION There is a need for early, objective markers of Alzheimer's disease (AD)‐related synapse dysfunction in adults with Down syndrome (DS). The presynaptic protein β‐synuclein is elevated in the blood of adults with DS. This study evaluates the positioning of these changes relative to changes in pathophysiological blood biomarkers ...
Cervantes González A, Morcillo-Nieto AO, Serrano S, Benejam B, Videla L, Barroeta I, Fernández S, Del Hoyo Soriano L, Hernandez AS, Maure-Blesa L, Vaqué-Alcázar L, Arranz J, Rodríguez-Baz Í, Aranha MR, Perlaza D, Lidón L, Alcolea D, Bejanin A, Carmona-Iragui M, Fortea J, Lleó A, Otto M, Oeckl P, Belbin O.   +23 more
europepmc   +2 more sources

Methodological insights and clinical outcomes in ALS and FTLD: lessons from the SPIN cohort. [PDF]

Alzheimers Dement
Abstract INTRODUCTION Amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) constitute a clinico‐genetic‐neuropathological continuum with marked heterogeneity. Reliable in vivo biomarkers of the disease are lacking. Large, multimodal cohorts are needed to advance biomarker discovery and precision medicine. METHODS We describe
Carbayo Á, Turon-Sans J, Alcolea D, Cortés-Vicente E, Cabezas-Torres M, Alvarez-Sanchez E, Muñoz L, Rubio-Guerra S, García-Castro J, Selma-González J, Bernal S, Gonzalez-Quereda L, Bejanin A, Aranha MR, Santos-Santos M, Belbin O, Vesperinas-Castro A, Collet-Vidiella R, Caballero-Ávila M, Llansó L, Querol L, Lleó A, Fortea J, Gelpí E, Dols-Icardo O, Illán-Gala I, Rojas-Garcia R.   +26 more
europepmc   +2 more sources

Diagnosis of prodromal and Alzheimer's disease dementia in adults with Down syndrome using neuropsychological tests

Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2020
Introduction We aimed to define prodromal Alzheimer's disease (AD) and AD dementia using normative neuropsychological data in a large population‐based cohort of adults with Down syndrome (DS). Methods Cross‐sectional study.
Bessy Benejam, Laura Videla, Eduard Vilaplana, Isabel Barroeta, Maria Carmona‐Iragui, Miren Altuna, Silvia Valldeneu, Susana Fernandez, Sandra Giménez, Florencia Iulita, Diana Garzón, Alexandre Bejanin, David Bartrés‐Faz, Sebastià Videla, Daniel Alcolea, Rafael Blesa, Alberto Lleó, Juan Fortea   +17 more
doaj   +1 more source

Desigualdad de género, inclusión laboral y riesgos psicosociales: evidencias en trabajadoras con discapacidad intelectual

Cuestiones de Género: de la Igualdad y la Diferencia, 2014
El empleo es un factor clave para garantizar la igualdad de oportunidades.  Las mujeres con discapacidad intelectual se encuentran en una situación de doble desventaja que dificulta su inclusión laboral.
Noelia Flores, Cristina Jenaro, Paula Martinelli, Vanessa Vega   +3 more
doaj   +1 more source

Anomalías congénitas del riñón y del tracto urinario en niños con síndrome de Down

Revista Colombiana de Nefrología, 2018
Las anomalías del riñón y el tracto urinario hacen parte de las anomalías congénitas relacionadas con el síndrome de Down. No existen recomendaciones específicas.
Víctor Manuel Mora-Bautista
doaj   +1 more source

The development of social skills of people with functional diversity. Through the creative process

Arteterapia, 2017
The development of social skills are an essential condition to promote so that people with functional diversity can lead a full life as normalized as possible under the principles of integration. In this article we will present research that analyzes how
Dara Alonso Arana
doaj   +1 more source

Práctica escénica como investigación: metodología situada de investigación-creación en robot: Ecos Neurodivergentes

Intervención
En el contexto de las artes escénicas chilenas, las nociones de normalidad y capacidad continúan configurando formas de exclusión que limitan la participación de personas neurodivergentes y con discapacidad.
Victor Ignacio Romero-Rojas, Genesis Baez Zepeda   +1 more
doaj   +1 more source

A structured multidisciplinary home parenteral nutrition program in a public healthcare system: Implementation model, nursing‐led training protocol, and 11‐year safety outcomes

Nutrition in Clinical Practice, EarlyView.
Abstract Background Home parenteral nutrition (HPN) is the standard of care for adults with chronic intestinal failure (CIF), but evidence from publicly funded healthcare systems in middle‐income countries is limited. This study describes an 11‐year experience of a structured, nursing‐led HPN program within Brazil's Unified Health System (SUS ...
Tatiana da Cunha Rana, Mariana Hollanda Martins da Rocha, Luiz Augusto Carneiro d'Albuquerque, André Dong Won Lee, Wellington Andraus, Luciana Bertocco de Paiva Haddad   +5 more
wiley   +1 more source

The disability variable in chilean cultural policy: evaluation and challenges

Revista Chilena de Terapia Ocupacional, 2017
Introduction: The origin of the disability is not only in the individual. It is on the interaction between individual and contextual factors and these last ones determine opportunities of participation.
Paula Milenka Cancino González, Alejandra Karina Reinoso Aguiló, Constanza Edith Rojas Rodríguez   +2 more
doaj   +1 more source

Community assembly on inland cliffs is context‐dependent

Functional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Under harsh environmental conditions, community assembly processes are expected to drive pronounced functional convergence, with communities dominated by stress‐tolerant species.
Thomas Deola, Gianmaria Bonari, Alessandro Bricca, Leopoldo de Simone, Sofie Paulus, Claudia Angiolini, Francesco Candini, Juan Lorite, Manuel J. Steinbauer, Anke Jentsch   +9 more
wiley   +1 more source