Results 11 to 20 of about 151,000 (163)

Three-Step One-Pot Photocatalytic Oxidation of Feedstocks and Organocatalytic Sequential Cascade to Access Enantioenriched α-Aminonitriles. [PDF]

ChemSusChem
A one‐pot, three‐step cascade from simple feedstocks to chiral building blocks is reported. By merging organic photocatalysis and noncovalent organocatalysis, benzylic substrates are transformed into enantioenriched α‐aminonitriles via CH photooxidation, imine formation, and asymmetric Strecker reaction. The method affords good yields, up to 96:4 e.r.,
Perulli S, Ardevines S, Malagón S, Khassenova G, Hülße T, Marqués-López E, Herrera RP, García Mancheño O.   +7 more
europepmc   +2 more sources

SM-COLSARSPROT: Highly Immunogenic Supramutational Synthetic Peptides Covering the World’s Population

Frontiers in Immunology, 2022
Fifty ~20–amino acid (aa)–long peptides were selected from functionally relevant SARS-CoV-2 S, M, and E proteins for trial B-21 and another 53 common ones, plus some new ones derived from the virus’ main genetic variants for complementary trial C-21 ...
Manuel A. Patarroyo, Manuel E. Patarroyo, Laura Pabón, Martha P. Alba, Adriana Bermudez, María Teresa Rugeles, Diana Díaz-Arevalo, Wildeman Zapata-Builes, María Isabel Zapata, César Reyes, Carlos F. Suarez, William Agudelo, Carolina López, Jorge Aza-Conde, Miguel Melo, Luis Escamilla, Jairo Oviedo, Fanny Guzmán, Yolanda Silva, Martha Forero, Lizdany Flórez-Álvarez, Wbeimar Aguilar-Jimenez, Armando Moreno-Vranich, Jason Garry, Catalina Avendaño   +24 more
doaj   +1 more source

Synthesis and Structural Characterization of Phosphanide Gold(III)/Gold(I) Complexes and Their Thallium(III) and Gold(III) Precursors

Molecules, 2023
In this paper, we describe a series of diphenylphosphane and diphenylphosphanide gold(III) and gold(III)/gold(I) complexes containing 3,5-C6Cl2F3 as aryl ligands at gold that have been synthesized due to the arylating and oxidant properties of the new ...
Laura Coconubo-Guio, José M. López-de-Luzuriaga, Sonia Moreno, M. Elena Olmos   +3 more
doaj   +1 more source

Reaccions d'acoblament creuat: eines simples per a la construcció de molècules complexes [PDF]

, 2011
El premi Nobel de química de l'any 2010 ha reconegut el treball de tres químics que durant els anys 70 i 80 van obrir el camí a la realització de certes síntesis orgàniques que ara resulten fonamentals per a l'elaboració de substàncies d'interès en ...
Aliberas i Maymí, Joan, Maseras Cuní, Feliu   +1 more
core   +2 more sources

Iboga Inspired N-Indolylethyl-Substituted Isoquinuclidines as a Bioactive Scaffold: Chemoenzymatic Synthesis and Characterization as GDNF Releasers and Antitrypanosoma Agents

Molecules, 2022
The first stage of the drug discovery process involves the identification of small compounds with biological activity. Iboga alkaloids are monoterpene indole alkaloids (MIAs) containing a fused isoquinuclidine-tetrahydroazepine ring.
Mariana Pazos, Estefania Dibello, Juan Manuel Mesa, Dalibor Sames, Marcelo Alberto Comini, Gustavo Seoane, Ignacio Carrera   +6 more
doaj   +1 more source

Cytotoxic Gold(I) Complexes with Amidophosphine Ligands Containing Thiophene Moieties

Inorganics, 2019
A new phosphine ligand bearing a thiophene moiety, C4H3SNHCOCH2CH2PPh2 (L), has been prepared by reaction of the aminophosphine Ph2PCH2CH2NH2 with thiophenecarbonylchloride in the presence of triethylamine. The coordination behavior towards gold(I), gold(
Helen Goitia, M. Dolores Villacampa, Antonio Laguna, M. Concepción Gimeno   +3 more
doaj   +1 more source

[AuHg(o-C6H4PPh2)2I]: A Dinuclear Heterometallic Blue Emitter

Inorganics, 2015
The heteronuclear AuI/HgII complex [AuHg(o-C6H4PPh2)2I] (1) was prepared by reacting of [Hg(2-C6H4PPh2)2] with [Au(tht)2]ClO4 (1:1) and NaI in excess. The heterometallic compound 1 has been structurally characterized and shows an unusual blue luminescent
José M. López-de-Luzuriaga, Miguel Monge, M. Elena Olmos, David Pascual   +3 more
doaj   +1 more source

Synthesis of New Thiourea-Metal Complexes with Promising Anticancer Properties

Molecules, 2021
In this work, two thiourea ligands bearing a phosphine group in one arm and in the other a phenyl group (T2) or 3,5-di-CF3 substituted phenyl ring (T1) have been prepared and their coordination to Au and Ag has been studied.
Guillermo Canudo-Barreras, Lourdes Ortego, Anabel Izaga, Isabel Marzo, Raquel P. Herrera, M. Concepción Gimeno   +5 more
doaj   +1 more source

The key role of Au-substrate interactions in catalytic gold subnanoclusters

Nature Communications, 2017
Stabilization of gold nanoclusters in order to prevent their self-aggregation remains a great challenge. Here, the authors describe transient stabilization of very small catalytic gold subnanoclusters by alkyl chains or aromatic groups appended to the ...
Jesús Cordón, Gonzalo Jiménez-Osés, José M. López-de-Luzuriaga, Miguel Monge   +3 more
doaj   +1 more source

Acylhydrazone-based dynamic combinatorial libraries: study of the thermodynamic/kinetic evolution, configurational and coordination dynamics

Revista Colombiana de Química, 2016
The kinetic and thermodynamic selectivity of acylhydrazone formation in dynamic combinatorial libraries (DCL) is described. Competition reactions were generated from hydrazides: isoniazid, 4-nitro-benzohydrazide, 4-dimethylamino-benzohydrazide, and ...
Mónica Andrea Gordillo Varela, Fabio Zuluaga, Manuel Noé Chaur Valencia   +2 more
doaj   +1 more source