Results 171 to 180 of about 21,334,376 (275)

Synthesis of Novel BINOL Analogs: 3,3′‐Dicarbonyl‐1,1′‐binaphthyl‐4,4′‐diols as Precursors to the Uncharted 5,5′‐Binaphtho[2,1‐d]isoxazole

European Journal of Organic Chemistry, EarlyView.
The parent 5,5′‐binaphtho[2,1‐d]isoxazole and its 3,3′‐dimethyl and 3,3′‐diphenyl derivatives are synthesized via condensation of the respective dicarbonyl compounds with hydroxylamine, followed by cyclodehydration of the resulting dioximes. The dicarbonyl precursors are obtained through 4‐ or 6‐step sequences from 1‐naphthol or 1‐naphthaldehyde ...
Marek Surowiec, Ioannis E. Gerontitis, Petros G. Tsoungas, Panteleimon G. Takis, Panagiotis Stathopoulos, Erietta Pouliou, George Varvounis   +6 more
wiley   +1 more source

Pseudo-enzymatic S-acylation of a myristoylated Yes protein tyrosine kinase peptide in vitro may reflect non-enzymatic S-acylation in vivo [PDF]

, 1998
M. Carmen Bañó, S. Caroline JACKSON, I. Anthony MAGEE   +2 more
openalex   +1 more source

A New Methodology for Preparing Benzylated Aminopyridines Yields Previously Inaccessible Organocatalysts

European Journal of Organic Chemistry, EarlyView.
ZnBr2‐induced benzylation of 4‐aminopyridineswith suitable alcohols or diols provides access to novel organocatalysts of the unprecedented diarylpyrrolidionopyridine type, as well as new benzylmethylaminopyridine catalysts. These catalysts are practically inaccessible by other routes and exhibit high activity and site selectivity in the phosphorylation
Mikhail Kozlov, Fatma Saady, Or Fleischer, Shai Ben Sasson, Ibrahim Amer, Scott J. Miller, Moshe Portnoy   +6 more
wiley   +1 more source

Reviewer #2 (Public Review): S-acylation of NLRP3 provides a nigericin sensitive gating mechanism that controls access to the Golgi

openalex   +2 more sources

FoxO1-zDHHC4-CD36 S-Acylation Axis Drives Metabolic Dysfunction in Diabetes. [PDF]

Circ Res
Dennis KMJH, Gopal K, Montes Aparicio CN, Zhang JA, Castro-Guarda M, Nicol T, Devereux RM, Carter RD, Azizi SA, Lan T, Purnama U, Carr CA, Simsek G, Gill EK, Swietach P, Sorop O, Heinonen IHA, Schianchi F, Luiken JJFP, Aksentijevic D, Duncker DJ, Dickinson BC, De Val S, Ussher JR, Fuller W, Heather LC.   +25 more
europepmc   +1 more source

Synthesis of Unnatural Aplysiatoxin Analogs with High Affinity for Protein Kinase C

European Journal of Organic Chemistry, EarlyView.
In the course of synthetic study of aplysiatoxin, a potent protein kinase C (PKC) activator, it is serendipitously found that a five‐membered ether 1 obtained as an undesired product from alkyne‐containing macrodiolide 2 with Au catalyst shows a high affinity for PKC.
Mana Morishita, Kohei Hada, Yusuke Araki, Keisuke Fukaya, Daisuke Urabe, Ryo C. Yanagita, Jumpei Maki, Yusuke Hanaki, Masaki Kita, Kazuhiro Irie, Toshio Nishikawa   +10 more
wiley   +1 more source

A Salmonella typhimurium Effector Protein SifA Is Modified by Host Cell Prenylation and S-Acylation Machinery [PDF]

, 2005
Anna T. Reinicke, James L. Hutchinson, Anthony I. Magee, Pietro Mastroeni, John Trowsdale, Adrian P. Kelly   +5 more
openalex   +1 more source

Development of a Promising Bivalent Vaccine Against Klebsiella pneumoniae Based on Glycoengineered GMMA (geGMMA)

Exploration, EarlyView.
Multidrug‐resistant Klebsiella pneumoniae poses a significant threat as a nosocomial pathogen, with no current licensed vaccines available. This study used a mutant E. coli strain expressing exogenous polysaccharides (from K. pneumoniae) to establish glycoengineered generalized modules for membrane antigens (geGMMA) vaccine platform, which demonstrated
Jingqin Ye, Wenhua Huang, Shujuan Yu, Yan Guo, Peng Sun, Ziyuan Chen, Linhui Hao, Yan Zhang, Caixia Li, Yongqiang Jiang, Jun Wu, Li Zhu, Hengliang Wang, Chao Pan   +13 more
wiley   +1 more source

Identification of key features required for efficient S-acylation and plasma membrane targeting of Sprouty-2 [PDF]

, 2020
Carolina Locatelli, Kimon Lemonidis, Christine Salaün, Nicholas C. O. Tomkinson, Luke Chamberlain   +4 more
openalex   +1 more source

S-acylation stabilizes ligand-induced receptor kinase complex formation during plant pattern-triggered immune signaling

Current Biology, 2021
C. Hurst, Dionne Turnbull, Kaltra Xhelilaj, Sally M. Myles, Robin L. Pflughaupt, Michaela Kopischke, Paul Davies, Sue Jones, S. Robatzek, C. Zipfel, Julien Gronnier, P. Hemsley   +11 more
semanticscholar   +1 more source