Results 231 to 240 of about 37,527 (267)

Chemoenzymatically Synthesized O‐Acetylated GD3 Gangliosides to Examine Viral Receptor Specificities in a Cellular Context

Angewandte Chemie, Volume 138, Issue 2, 9 January 2026.
7‐O‐, 9‐O‐, and 7,9‐di‐O‐acetylated GD3 gangliosides can be prepared by chemical assembly of a tetrasaccharide as α‐glycosyl fluoride that is coupled to sphingosine using a glycosynthase, followed by O‐acetyl editing by coronaviral hemagglutinin‐esterases (HEs).
Zhiyong Zhang, Ruonan Liang, Kevin C. Hooijschuur, Robert P. de Vries, Zeshi Li, Geert‐Jan Boons   +5 more
wiley   +2 more sources

Control of PHYTOCHROME KINASE SUBSTRATE subcellular localization and biological activity by protein S-acylation

, 2022
Vazquez AL, Petrolati LA, Dessimoz C, Lampugnani ER, Glover N, Fankhauser C.   +5 more
europepmc   +1 more source

Covalent Activation of the C‐type Lectin DC‐SIGN

Angewandte Chemie International Edition, Volume 65, Issue 3, 16 January 2026.
We introduce the first covalent activators of a C‐type lectin. Using orthogonal functional assays, NMR, MS/MS, and computational modeling, we delineate mechanisms from a functional electrophile‐first screen on dendritic cell‐specific intercellular adhesion molecule‐3‐grabbing non‐integrin (DC‐SIGN) that yields two modes: N‐hydroxysuccinimide (NHS ...
Jonathan Lefèbre, Maurice Besch, Noémi Csorba, Kristóf Garami, Zoltán Orgován, Gitta Schlosser, Iris Bermejo, Péter Ábrányi‐Balogh, György M. Keserű, Christoph Rademacher   +9 more
wiley   +1 more source

Enantioconvergent Access to Chiral S(VI) Stereocenters by Kinetic Resolution of Sulfonimidoyl Chlorides

Angewandte Chemie, Volume 138, Issue 2, 9 January 2026.
An enantioconvergent approach for the kinetic resolution of S(VI) stereocenters that leverages the electrophilic reactivity of the chiral sulfur atom is described. The catalytic process provides access to sulfonimidoyl chlorides and sulfonimidates, which are among the least studied S(VI) functionalities.
Arko Das, Shree Krishna Dhakal, Ramon Trevino, Seth O. Fremin, Vy T. B. Nguyen, Arka Porey, Sachchida Nand, Chandan Kumar Giri, Daniel J. Wherritt, Hadi D. Arman, Oleg V. Larionov   +10 more
wiley   +2 more sources

Chemoselective Divergence via Substrate Control: Decarboxylative and Decarbonylative Coupling of 2‐Oxoacids with Allylic Difluorides

European Journal of Organic Chemistry, Volume 29, Issue 1, January 12, 2026.
A photocatalytic method for the decarboxylative CC coupling of 2‐oxoacids and allylic difluorides has been developed, yielding monofluoroalkenes in excellent yields. The reaction tolerates both aryl‐ and alkyl‐substituted 2‐oxoacids and displays high functional group tolerance.
Taylor Semeniuk, Austin Pounder, Dennis D. Toporkov, Stacey D. Wetmore, Jean‐Denys Hamel   +4 more
wiley   +1 more source

Site-Specific Identification of Protein S-Acylation by IodoTMT0 Labeling and Immobilized Anti-TMT Antibody Resin Enrichment. [PDF]

J Proteome Res
Cai J, Song M, Li M, Merchant M, Benz F, McClain C, Klein J.   +6 more
europepmc   +1 more source

The 5-hydroxytryptamine(4a) receptor is palmitoylated at two different sites and acylation is critically involved in regulation of receptor constitutive activity [PDF]

, 2002
Bickmeyer, Ulf, Dumuis, A., Heine, M., Loubert, L., Ponimaskin, E. G., Richter, D. W., Sebben, M.   +6 more
core  

Design of a Multienzyme Derived from Mouse Fatty Acid Synthase for the Compartmentalized Production of 2‐Pyrone Polyketides

Angewandte Chemie International Edition, Volume 65, Issue 2, 9 January 2026.
A multienzyme was formed and evaluated by covalently linking 4‐coumarate ligase (4CL1) from Piper methysticum to a non‐reducing murine fatty acid synthase. 4CL1 acylates the acyl carrier protein (ACP). The ketosynthase (KS) was engineered to accept the non‐native cinnamoyl substrate, which is elongated by malonyl‐CoA loaded via the malonyl‐acetyl ...
Felix Lehmann, Nadja Joachim, Carolin Parthun, Martin Grininger   +3 more
wiley   +1 more source

S-acylation regulates SQSTM1/p62-mediated selective autophagy. [PDF]

Autophagy
Huang X, Liu L, Yao J, Lin C, Xiang T, Yang A.   +5 more
europepmc   +1 more source

S-acylation and neuroinflammation: the therapeutic potential of zDHHC and deacylase modulation

Tiago A Duarte, Choa P. Ng, Jorge A. R. Salvador, Ludovico Pipitò, Jennifer Greaves, Vânia M. Moreira   +5 more
openalex   +1 more source