Results 251 to 260 of about 21,334,376 (275)
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Bis(acyl) Diselenides as Convenient Acylating Reagents
Chemistry Letters, 1989Abstract Bis(acyl) diselenides serve as useful acylating reagents for amines, alcohols, thiols, and organocopper compounds such as cuprate.
Sawako Hamanaka +3 more
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Analysis of S-Acylation of Proteins
2003Palmitoylation or S-acylation is the post-translational attachment of fatty acids to cysteine residues and is common among integral and peripheral mem brane proteins. Palmitoylated proteins have been found in every eukaryotic cell type examined (yeast, insect, and vertebrate cells), as well as in viruses grown in these cells.
Michael Veit +2 more
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STUDIES ON THE ACYLATION OF LYSOLECITHINS
Canadian Journal of Biochemistry and Physiology, 1963"Semi-synthetic" lecithins were prepared by the acylation of lysolecithin cadmium chloride complexes (the lysolecithins were produced from egg lecithin by hydrolysis with phospholipase A) in the presence of pyridine with 1-C14myristoyl chloride. The labelled lecithins were hydrolyzed with phospholipase A to yield free fatty acids (94% of the label) and
J. R. Bennett, Neil H. Tattrie
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Alkylation and Acylation of Cyclotriphosphazenes
Inorganic Chemistry, 2007Phosphazenes (RNH)6P3N3 (R = n-propyl, isobutyl, isopropyl, cyclohexyl, tert-butyl, benzyl) are readily alkylated at ring N sites by alkyl halides forming N-alkyl phosphazenium cations. Alkylation of two ring N sites occurred after prolonged heating in the presence of methyl iodide or immediately at room temperature with methyl triflate yielding N,N ...
M. A. Benson +4 more
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Acyl-CoA dependent acylation of phospholipids in the chloroplast envelope
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2000Acyl-CoAs are substrates for acyl lipid synthesis in the endoplasmic reticulum. In addition, they may also be substrates for lipid acylation in other membranes. In order to assess whether lipid acylation may have a role in plastid lipid metabolism, we have studied the incorporation of radiolabelled fatty acids from acyl-CoAs into lipids in isolated ...
Mats X. Andersson +3 more
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Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1970
1. 1. A particulate fraction of Escherichia coli catalyzes the transfer of palmitate from palmityl-CoA and palmityl-acyl carrier protein to sn-glycero-3-phosphate. When a series of long-chain acyl thiolesters including myristyl-, palmityl-, palmitoleyl- and cis-vaccenyl-CoA and acyl carrier protein were tested in the acylation of sn-glycero-3 ...
P. Roy Vagelos, H. Van Den Bosch
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1. 1. A particulate fraction of Escherichia coli catalyzes the transfer of palmitate from palmityl-CoA and palmityl-acyl carrier protein to sn-glycero-3-phosphate. When a series of long-chain acyl thiolesters including myristyl-, palmityl-, palmitoleyl- and cis-vaccenyl-CoA and acyl carrier protein were tested in the acylation of sn-glycero-3 ...
P. Roy Vagelos, H. Van Den Bosch
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Effective Synthesis of 1β-Acyl Glucuronides by Selective Acylation
Organic Letters, 2005[reaction: see text] Acyl glucuronides are vital metabolites for many carboxylic acid containing drugs. We report an efficient new method for the chemical synthesis of these molecules by selective 1beta-acylation of allyl glucuronate with carboxylic acids catalyzed by HATU and then mild deprotection through treatment with Pd(PPh(3))(4) and morpholine ...
Atholl Johnston +5 more
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And then there were acyl coenzyme A:cholesterol acyl transferase inhibitors
Current Opinion in Lipidology, 2006The reputation of acyl coenzyme A:cholesterol acyltransferase (ACAT) inhibitors has changed profoundly from promising new drugs for cardiovascular prevention to drugs without clinical benefits or possibly even with adverse effects.ACAT inhibitors decrease the intracellular conversion of free cholesterol into cholesteryl ester in a number of tissues ...
Erik S.G. Stroes +3 more
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Design, synthesis and biological activity evaluation of novel covalent S-acylation inhibitors.
Molecular diversity, 2023Wei Yu +7 more
semanticscholar +1 more source