Results 151 to 160 of about 60,031 (297)
S-Adenosylmethionine Increases the Sensitivity of Human Colorectal Cancer Cells to 5-Fluorouracil by Inhibiting P-Glycoprotein Expression and NF-κB Activation [PDF]
Laura Mosca +7 more
openalex +1 more source
Epigenomics‐guided precision oncology: Chromatin variants in prostate tumor evolution
Abstract Prostate cancer is a common malignancy that in 5%–30% leads to treatment‐resistant and highly aggressive disease. Metastasis‐potential and treatment‐resistance is thought to rely on increased plasticity of the cancer cells—a mechanism whereby cancer cells alter their identity to adapt to changing environments or therapeutic pressures to create
Kira Furlano +6 more
wiley +1 more source
AhR and SHP regulate phosphatidylcholine and S-adenosylmethionine levels in the one-carbon cycle [PDF]
Young‐Chae Kim +9 more
openalex +1 more source
Epigenetic reprogramming in multiple myeloma—Challenges and opportunities
Abstract In cancer, mutational processes act in concert with epigenetic reprogramming to endow malignant cells with hallmark properties that underpin tumorigenesis. Compared with the relatively rigid and slow processes of genetic evolution, the plastic nature of chromatin enables cells to adapt to a changing environment more rapidly.
Subhasree Kumar +2 more
wiley +1 more source
Overproduction of cardiac S-adenosylmethionine decarboxylase in transgenic mice [PDF]
Oleg Nisenberg +4 more
openalex +1 more source
Die N‐Methyltransferase SgPsmC wurde charakterisiert und für die kinetische Racematspaltung von Pyrroloindolinen verwendet. Die Substitution an 3a‐Position erwies sich als eine Hauptdeterminante für die Enantioselektivität des Enzyms. Die Reaktion wurde mit einer Methionin‐Adenosyl‐Transferase gekoppelt, um S‐Adenosylmethionin in situ zu erzeugen und ...
Benjamin Panagiotis Chapple +7 more
wiley +1 more source
Enrichment of Hypermethylated DNA on Chip for Cervical Cancer Detection
A microfluidic chip coated with surface‐immobilized methyl binding domain 2 (MBD‐2) protein receptors, is able to bind hypermethylated DNA (hmDNA) from a cancer cell line selectively. Quantification by quantitative polymerase chain reaction (qPCR) shows a 30‐fold enrichment in cervical cancer target DNA.
Ruben W. Kolkman +7 more
wiley +1 more source

