Results 171 to 180 of about 25,478 (242)

Metabolomics in cardiometabolic diseases: Key biomarkers and therapeutic implications for insulin resistance and diabetes

open access: yesJournal of Internal Medicine, Volume 297, Issue 6, Page 584-607, June 2025.
Abstract Cardiometabolic diseases—including Type 2 diabetes and obesity—remain leading causes of global mortality. Recent advancements in metabolomics have facilitated the identification of metabolites that are integral to the development of insulin resistance, a characteristic feature of cardiometabolic disease. Key metabolites, such as branched‐chain
David Rizo‐Roca   +2 more
wiley   +1 more source

Natural History of Idiosyncratic Drug‐Induced Liver Injury and Prognostic Models

open access: yesLiver International, Volume 45, Issue 6, June 2025.
ABSTRACT Background and Aims: Drug‐induced liver injury (DILI) remains a leading cause of acute liver failure worldwide. Drugs such as isoniazid, alone or in combination with other anti‐tuberculosis drugs, as well as a growing number of herbal and complementary medicines, have been implicated in most cases of acute liver failure in registry studies ...
Harshad C. Devarbhavi, Raúl J. Andrade
wiley   +1 more source

Characterization of a S-Adenosylmethionine Synthetase Gene in Rice [PDF]

open access: bronze, 1994
Frank Van Breusegem   +4 more
openalex   +1 more source

How eriophyid mites shape metal metabolism in leaf galls on Tilia cordata

open access: yesNew Phytologist, Volume 246, Issue 5, Page 2222-2242, June 2025.
Summary Metal metabolism in plant–galler interactions is largely unknown. We hypothesise that the mites manipulate metal distribution by sequestration of excessive levels and differential regulation of metalloproteins to support the main functions of gall‐nutrition, protection and microenvironment.
Filis Morina   +8 more
wiley   +1 more source

Elucidating the enzyme network driving Amaryllidaceae alkaloids biosynthesis in Leucojum aestivum

open access: yesPlant Biotechnology Journal, Volume 23, Issue 6, Page 1988-2005, June 2025.
Schematic representation of Amaryllidaceae alkaloid biosynthesis in Leucojum aestivum. Norbelladine synthase (LaNBS) and noroxomaritidine/norcraugsodine reductase (LaNRII) catalyze the condensation of tyramine and 3,4‐dihydroxybenzaldehyde to form norbelladine, which is subsequently O‐methylated by norbelladine‐4′‐O‐methyltransferase (LaN4′OMT ...
Basanta Lamichhane   +6 more
wiley   +1 more source

The Crucial Roles of Phloem Companion Cells in Response to Phosphorus Deficiency

open access: yesPlant, Cell &Environment, Volume 48, Issue 6, Page 4327-4340, June 2025.
ABSTRACT Mineral deficiency is a major problem in agriculture. Plant adaption to low mineral environments involves signaling between shoots and roots, via the food transport cells, the sieve elements. However, due to the sequestered position of the sieve elements in the vascular bundles, identifying shoot‐to‐root mobile signals is challenging.
Chao Xia   +7 more
wiley   +1 more source

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