Results 121 to 130 of about 4,010,875 (229)

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Breastfeeding and risk of hospitalisation in children under five years-a systematic review and meta-analysis. [PDF]

Front Pediatr
Kerketta S, Sethy P, Swain S, Pradhan S, Sahu S, Sahoo R, Munda M, Kanungo S, Srinivasan M, Pati S.   +9 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Five times sit-to-stand test performance in Parkinson\u27s disease [PDF]

, 2011
Duncan, Ryan P, Earhart, Gammon M, Leddy, Abigail L   +2 more
core   +1 more source

How many trials are enough? Familiarization requirements in the Loughborough Soccer Passing Test. [PDF]

BMC Sports Sci Med Rehabil
Yaşlı BÇ, Karayiğit R, Önlü AŞ, Esen Ö, Mareș G, Alexe DI, Lupu GS, Alexe CI.   +7 more
europepmc   +1 more source

Design and Validation of a Discipline-Oriented Curriculum Model for Elementary Education with an Emphasis on Gardner\'s Five Minds Approach

Iranian Evolutionary Educational Psychology Journal
Objective: The aim of this research was to design and validate a discipline-oriented curriculum model for elementary education with an emphasis on Gardner's Five Minds approach. Methods: This study employed a mixed exploratory sequential research method. Initially, the desired model was developed through qualitative methods (synthetic literature review
Mehzad Alirezaei, Faezeh Nateghi, Mohammad Seifi   +2 more
openaire   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

A Pilot Metagenomic Study Demonstrating Virtual Reality Head Mounted Displays Utilized in Medical Education Are Reservoirs of Viable Pathogenic Microbes. [PDF]

Microbiologyopen
Goldsworthy A, Olsen M, Shiratuddin MF, McKirdy S, Alghafri R, Senok A, Alfalasi H, Wong KW, Tajouri L.   +8 more
europepmc   +1 more source