Results 41 to 50 of about 4,010,875 (229)
C-elegans model identifies genetic modifiers of alpha-synuclein inclusion formation during aging [PDF]
, 2008 Inclusions in the brain containing alpha-synuclein are the pathological hallmark of Parkinson's disease, but how these inclusions are formed and how this links to disease is poorly understood.
AA Cooper +38 more
core +8 more sources
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Wholeness as a Hierarchical Graph to Capture the Nature of Space
, 2015 According to Christopher Alexander's theory of centers, a whole comprises numerous, recursively defined centers for things or spaces surrounding us. Wholeness is a type of global structure or life-giving order emerging from the whole as a field of the ...
Jiang, Bin
core +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
How to gain competitive advantage through crossborder e-commerce between New Zealand and China? [PDF]
, 2017 With the popularization of the Internet and the explosive growth of cross-border e-commerce, this research project discusses how an organisation can gain competitive advantage through cross-border e-commerce.
Chen, Cheng +1 more
core
Epidemiology of diabetes mellitus among 193,435 cats attending primary-care veterinary practices in England [PDF]
, 2016 BACKGROUND: Diabetes mellitus (DM) is a common endocrine disease of cats. The prevalence of DM in cats in England is not well‐defined. HYPOTHESIS/OBJECTIVES: To estimate the prevalence and identify risk factors for DM in a large population of cats ...
Brodbelt, D C +6 more
core +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Letter Written by Katherine Trickey to Her Folks Dated January 15, 1944 [PDF]
, 1944 First part of letter typed [Transcription begins] WAC Det. IRTC Camp Wheeler, Georgia Sat.
Trickey, Katherine W.
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Spartan Daily, October 3, 1939 [PDF]
, 1938 Volume 28, Issue 9https://scholarworks.sjsu.edu/spartandaily/2955/thumbnail ...
San Jose State University, School of Journalism and Mass Communications
core +2 more sources