Results 91 to 100 of about 6,811 (158)

Glutathione S-transferases and S-glutathionylation in cancer

Biomedicine & Pharmacotherapy, 2008
CN04-02 The glutathione-S-transferase (GST) super family comprises multiple isozymes (Alpha, Mu, Pi, Omega, Theta, and Zeta) with evidence of functional polymorphic variations. Correlative studies have shown that genetic differences of GST isozyme expression may contribute to cancer susceptibility and treatment.
openaire   +1 more source

Glutaredoxin-1 modulates the NF-κB signaling pathway to activate inducible nitric oxide synthase in experimental necrotizing enterocolitis

Molecular Therapy: Methods & Clinical Development
Inducible nitric oxide synthase (iNOS), regulated by nuclear factor kappa B (NF-κB), is crucial for intestinal inflammation and barrier injury in the progression of necrotizing enterocolitis (NEC). The NF-κB pathway is inhibited by S-glutathionylation of
Yunfei Zhang, Mei Yan, Yingying Xia, Yingbin Yue, Shuli Wang, Yuhui Hu, Genjian Lai, Quanjiang Wu, Qianyang Liu, Xin Ding, Chunbao Guo   +10 more
doaj   +1 more source

Implications of S-glutathionylation of sarcomere proteins in cardiac disorders, therapies, and diagnosis. [PDF]

Front Cardiovasc Med, 2022
Rosas PC, Solaro RJ.
europepmc   +1 more source

Defining the S-Glutathionylation Proteome by Biochemical and Mass Spectrometric Approaches. [PDF]

Antioxidants (Basel), 2022
Li X, Zhang T, Day NJ, Feng S, Gaffrey MJ, Qian WJ.   +5 more
europepmc   +1 more source

Polysulfides promote protein disulfide bond formation in microorganisms growing under anaerobic conditions

Applied and Environmental Microbiology
Polysulfides commonly occur in anaerobic, microbial active environments, where they play key roles in sulfur cycling and redox transformations. Anaerobic survival of microorganisms requires the formation of protein disulfide bond (DSB).
Yuping Xin, Qingda Wang, Jianming Yang, Xiaohua Wu, Yongzhen Xia, Luying Xun, Huaiwei Liu   +6 more
doaj   +1 more source

S-Glutathionylation and S-Nitrosylation in Mitochondria: Focus on Homeostasis and Neurodegenerative Diseases. [PDF]

Int J Mol Sci, 2022
Vrettou S, Wirth B.
europepmc   +1 more source

GSTP1-mediated S-glutathionylation of Pik3r1 is a redox hub that inhibits osteoclastogenesis through regulating autophagic flux. [PDF]

Redox Biol, 2023
Ji X, Hong J, Yang W, Yao M, Wang J, Jiang G, Wang Y, Li C, Lin J, Mou H, Li C, Li S, Chen Y, Shi M, Wang W, Lu F, Wu H, Zhao X, Qi Y, Yan S.   +19 more
europepmc   +1 more source

Glutamine promotes O-GlcNAcylation of G6PD and inhibits AGR2 S-glutathionylation to maintain the intestinal mucus barrier in burned septic mice. [PDF]

Redox Biol, 2023
Wu D, Su S, Zha X, Wei Y, Yang G, Huang Q, Yang Y, Xia L, Fan S, Peng X.   +9 more
europepmc   +1 more source

Helicase-like transcription factor (HLTF)-deleted CDX/TME model of colorectal cancer increased transcription of oxidative phosphorylation genes and diverted glycolysis to boost S-glutathionylation in lymphatic intravascular metastatic niches. [PDF]

PLoS One, 2023
Martinez-Marin D, Helmer RA, Kaur G, Washburn RL, Martinez-Zaguilan R, Sennone SR, Dufour JM, Chilton BS.   +7 more
europepmc   +1 more source

Sputum Glutaredoxin 1 and Protein S-Glutathionylation in COPD. [PDF]

Antioxidants (Basel)
Kuipers I, Krijgsman R, Louis R, Corhay JL, Azevedo Mendes T, Brusselle GG, Bracke KR, Reynaert NL.   +7 more
europepmc   +1 more source