Results 71 to 80 of about 4,282,430 (283)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Characterization of uniaxial fatigue behavior of precipitate strengthened Cu-Ni-Si alloy (SICLANIC(TM))

open access: yesFracture and Structural Integrity, 2017
Fatigue tests were conducted on cylindrical bars specimens to understand the fatigue behavior of SICLANIC®. Although it displays good resistance in monotonic tension, this material weakens and shows a softening in repeated solicitation.
B. Saadouki   +4 more
doaj  

Fatigue Damage Characteristics of Offshore Wind Power Large-Diameter Monopile Structures During Driving Process

open access: yes南方能源建设
[Objective] Large-diameter monopile foundations are widely used in marine engineering in China and are typically installed through penetration. Due to the impact of the pile hammer, the pile body experiences continuous impact loads during the driving ...
Tao CHEN   +4 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Life Prediction of Flexspline based on the Modified P-S-N Curve

open access: yesJixie chuandong, 2021
By using Hypermesh to mesh the harmonic reducer and utilizing Abaqus to complete its transient analysis. Based on the results of transient analysis,the position of the dangerous point of the flexspline is determined,a method of extracting and ...
Qingwen Huang, Baisheng Wu, Delin Liao
doaj  

Estimation Method of Micropitting Life from S-N Curve Established by Residual Stress Measurements and Numerical Contact Analysis

open access: yesTribology Online, 2019
Micropitting is a type of rolling contact fatigue (RCF) associated with rough surfaces and severe lubrication conditions. In the present study, we developed an estimation method for micropitting life.
Naoya Hasegawa   +4 more
doaj   +1 more source

The effect of anisotropic emission on the log N-log S curve of gamma-ray bursts [PDF]

open access: yes
Some models for Gamma-Ray Burst spectra result in anisotropic emission.
Pizzichini, G.
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Review of vibration fatigue life analysis methods with mean stress

open access: yesHangkong gongcheng jinzhan
Vibration fatigue with mean stress widely exists in various engineering structures, while researchers have different solving methods. In order to compare and discuss the applicability of these methods, literature on fatigue life evaluation with mean ...
LI Mengnan, YAO Weixing
doaj   +1 more source

Building hyperbolic metrics suited to closed curves and applications to lifting simply

open access: yes, 2016
Let $\gamma$ be an essential closed curve with at most $k$ self-intersections on a surface $\mathcal{S}$ with negative Euler characteristic. In this paper, we construct a hyperbolic metric $\rho$ for which $\gamma$ has length at most $M \cdot \sqrt{k ...
Aougab, Tarik   +3 more
core  

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