S-Nitrosoglutathione Reductase—The Master Regulator of Protein S-Nitrosation in Plant NO Signaling [PDF]
Plants, 2019 S-nitrosation has been recognized as an important mechanism of protein posttranslational regulations, based on the attachment of a nitroso group to cysteine thiols.
Jana Jahnová +2 more
exaly +5 more sources
Regulation of B cell functions by S-nitrosoglutathione in the EAE model [PDF]
Redox Biology, 2021 B cells play both protective and pathogenic roles in T cell-mediated autoimmune diseases by releasing regulatory vs. pathogenic cytokines. B cell-depleting therapy has been attempted in various autoimmune diseases but its efficacy varies and can even ...
Judong Kim +6 more
doaj +3 more sources
Roles and current applications of S-nitrosoglutathione in anti-infective biomaterials [PDF]
Materials Today Bio, 2022 Bacterial infections can compromise the physical and biological functionalities of humans and pose a huge economical and psychological burden on infected patients.
Hu Qian, Zhimin Ye, Lanping Pi, Jun Ao
doaj +3 more sources
Endogenous Biosynthesis of S-Nitrosoglutathione From Nitro-Fatty Acids in Plants [PDF]
Frontiers in Plant Science, 2020 Nitro-fatty acids (NO2-FAs) are novel molecules resulting from the interaction of unsaturated fatty acids and nitric oxide (NO) or NO-related molecules. In plants, it has recently been described that NO2-FAs trigger an antioxidant and a defence response ...
Capilla Mata-Pérez +9 more
doaj +3 more sources
Improvement in Outcomes After Cardiac Arrest and Resuscitation by Inhibition of S-Nitrosoglutathione Reductase [PDF]
Circulation, 2019 Background: The biological effects of nitric oxide are mediated via protein S-nitrosylation. Levels of S-nitrosylated protein are controlled in part by the denitrosylase, S-nitrosoglutathione reductase (GSNOR).
Eizo Marutani, , Shuichi Hirai
exaly +3 more sources
S-Nitrosoglutathione (GSNO)-Mediated Lead Detoxification in Soybean through the Regulation of ROS and Metal-Related Transcripts. [PDF]
Int J Mol Sci, 2023 Heavy metal toxicity, including lead (Pb) toxicity, is increasing in soils, and heavy metals are considered to be toxic in small amounts. Pb contamination is mainly caused by industrialization (e.g., smelting and mining), agricultural practices (e.g ...
Methela NJ +4 more
europepmc +2 more sources
Frontiers in Plant Science, 2021 Nitric oxide (NO) is a short-lived radical gas that acts as a signaling molecule in all higher organisms, and that is involved in multiple plant processes, including germination, root growth, and fertility.
Patrick Treffon +5 more
doaj +2 more sources
S‐Nitrosoglutathione Reductase Deficiency Causes Aberrant Placental S‐Nitrosylation and Preeclampsia [PDF]
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022 Background Preeclampsia, a leading cause of maternal and fetal mortality and morbidity, is characterized by an increase in S‐nitrosylated proteins and reactive oxygen species, suggesting a pathophysiologic role for dysregulation in nitrosylation and ...
Shathiyah Kulandavelu +11 more
doaj +2 more sources
S-nitrosoglutathione reductase maintains mitochondrial homeostasis by promoting clearance of damaged mitochondria in porcine preimplantation embryos. [PDF]
Cell Prolif, 2021 S‐nitrosoglutathione reductase (GSNOR), a protein denitrosylase, protects the mitochondria from mitochondrial nitrosative stress. Mammalian preimplantation embryos are mitochondria‐rich, but the effects of GSNOR on mitochondrial function in ...
Niu YJ, Zhou D, Cui XS.
europepmc +2 more sources
S-Nitrosoglutathione protects acute kidney injury in septic rats by inhibiting the activation of NLRP3 inflammasome [PDF]
Iranian Journal of Basic Medical Sciences, 2023 Objective(s): We aimed to study the effect of S-nitroso glutathione (SNG) on acute kidney injury (AKI) in septic rats by regulating nucleotide oligomerization domain-like receptor protein 3 (NLRP3).Materials and Methods: Sprague Dawley rats were used to ...
Heng Fan +3 more
doaj +2 more sources