Results 31 to 40 of about 21,171,580 (198)
S-Nitrosoglutathione Reductase Is Essential for Protecting the Female Heart From Ischemia-Reperfusion Injury. [PDF]
Circ Res, 2018 Rationale: Protein S-nitros(yl)ation (SNO) has been implicated as an essential mediator of nitric oxide-dependent cardioprotection. Compared with males, female hearts exhibit higher baseline levels of protein SNO and associated with this, reduced ...
Casin KM +9 more
europepmc +2 more sources
Gender differences in S-nitrosoglutathione reductase activity in the lung.
PLoS ONE, 2010 S-nitrosothiols have been implicated in the etiology of various pulmonary diseases. Many of these diseases display gender preferences in presentation or altered severity that occurs with puberty, the mechanism by which is unknown. Estrogen has been shown
Kathleen Brown-Steinke +3 more
doaj +4 more sources
Antioxidants, 2021 In the past, reactive nitrogen species (RNS) were supposed to be stress-induced by-products of disturbed metabolism that cause oxidative damage to biomolecules.
Eva Esther Rudolf +10 more
doaj +1 more source
Biochimica et Biophysica Acta (BBA) - General Subjects, 2013 S-Nitrosoglutathione (GSNO) is the S-nitrosated derivative of glutathione and is thought to be a critical mediator of the down stream signaling effects of nitric oxide (NO). GSNO has also been implicated as a contributor to various disease states.This review focuses on the chemical nature of GSNO, its biological activities, the evidence that it is an ...
Katarzyna A, Broniowska +2 more
openaire +2 more sources
Glutathione in Protein Redox Modulation through S-Glutathionylation and S-Nitrosylation
Molecules, 2021 S-glutathionylation and S-nitrosylation are reversible post-translational modifications on the cysteine thiol groups of proteins, which occur in cells under physiological conditions and oxidative/nitrosative stress both spontaneously and enzymatically ...
Elena Kalinina, Maria Novichkova
doaj +1 more source
Recovery of reduced thiol groups by superoxide-mediated denitrosation of nitrosothiols
Redox Biology, 2022 Nitrosation of critical thiols has been elaborated as reversible posttranslational modification with regulatory function in multiple disorders. Reversibility of S-nitrosation is generally associated with enzyme-mediated one-electron reductions, catalyzed
Stefan Schildknecht +5 more
doaj +1 more source
Frontiers in Plant Science, 2013 S-nitrosoglutathione reductase (GSNOR) is believed to modulate effects of reactive oxygen and nitrogen species through catabolism of S-nitrosoglutathione (GSNO).
Shengbao eXu +3 more
doaj +1 more source
Pharmaceutics, 2020 S-nitrosoglutathione (GSNO) has emerged as a potent agent for the treatment of infected cutaneous wounds. However, fabrication of GSNO-containing nanoparticles has been challenging due to its high hydrophilicity and degradability. The present study aimed
Juho Lee +7 more
semanticscholar +1 more source
Frontiers in Plant Science, 2016 The levels of nitric oxide (NO) and reactive oxygen species (ROS), ATP/ADP ratios, reduction levels of ascorbate and glutathione, expression of the genes encoding proteins involved in metabolism of NO and activities of the enzymes involved in ...
Zhenguo eMa +6 more
doaj +1 more source
S-nitrosoglutathione Prevents Experimental Cerebral Malaria [PDF]
Journal of Neuroimmune Pharmacology, 2012 Administration of the exogenous nitric oxide (NO) donor dipropylenetriamine-NONOate (DPTA-NO) to mice during Plasmodium berghei ANKA (PbA) infection largely prevents development of experimental cerebral malaria (ECM). However, a high dose (1 mg/mouse twice a day) is necessary and causes potent side effects such as marked hypotension.
Graziela M, Zanini +4 more
openaire +2 more sources