Results 51 to 60 of about 21,171,580 (198)

Structural snapshots of nitrosoglutathione binding and reactivity underlying S-nitrosylation of photosynthetic GAPDH

open access: yesRedox Biology, 2022
S-nitrosylation is a redox post-translational modification widely recognized to play an important role in cellular signaling as it can modulate protein function and conformation.
Edoardo Jun Mattioli   +12 more
doaj   +1 more source

Responsive nitric oxide‐releasing antibacterial materials for biofilm‐associated infections: Mechanisms, design strategies, and applications

open access: yesResponsive Materials, EarlyView.
This review summarizes the recent progress in responsive NO‐releasing materials and their applications in biofilm‐associated infectious diseases. The design principles and response mechanisms are given to provide inspiration toward the future development of multi‐responsive NO‐releasing materials.
Wenyue Sun   +8 more
wiley   +1 more source

Unveiling Gut Homeostasis Disruption in Sepsis: Towards an Integrated Mechanistic and Translational Roadmap

open access: yesCell Proliferation, Volume 59, Issue 8, August 2026.
Elucidating the contribution of gut‐organ axes will provide new insights for developing combined therapeutic strategies against sepsis‐associated multiple organ dysfunction. ABSTRACT Sepsis, a life‐threatening clinical syndrome precipitated by a maladaptive host response to infection, is associated with substantial morbidity and high mortality rates ...
Yichen Bao   +7 more
wiley   +1 more source

Analysis of NIA and GSNOR family genes and nitric oxide homeostasis in response to wheat-leaf rust interaction

open access: yesScientific Reports, 2022
Nitric oxide (NO) modulates plant response to biotic and abiotic stresses by S-nitrosylation-mediated protein post-translational modification. Nitrate reductase (NR) and S-nitrosoglutathione reductase (GSNOR) enzymes are essential for NO synthesis and ...
Deepak T. Hurali   +8 more
doaj   +1 more source

Role of quinones in the ascorbate reduction rates of S-nitrosoglutathione [PDF]

open access: yesFree Radical Biology and Medicine, 2010
Quinones are one of the largest classes of antitumor agents approved for clinical use, and several antitumor quinones are in various stages of clinical and preclinical development. Many of these are metabolites of, or are, environmental toxins. Because of their chemical structure they are known to enhance electron transfer processes such as ascorbate ...
Pedro, Sanchez-Cruz   +2 more
openaire   +2 more sources

Hydrogen Gas Enhances Salinity Tolerance in Tomato Seedlings by Regulating the S‐Nitrosylation of MEK1

open access: yesPlant Biotechnology Journal, Volume 24, Issue 6, Page 3656-3678, June 2026.
ABSTRACT Hydrogen gas (H2) effectively alleviates abiotic stress in horticultural plants. Protein S‐nitrosylation, a key post‐translational modification, serves as a critical mechanism for nitric oxide (NO) to exert its biological function under adverse conditions.
Hua Fang   +12 more
wiley   +1 more source

Nitric Oxide‐Generating Poly (allylamine hydrochloride) Coating on Biomedical Titanium Implant

open access: yesAdvanced Materials Interfaces, Volume 13, Issue 10, 19 May 2026.
We report a metal‐free, nitric oxide (NO)‐generating coating in which poly(allylamine hydrochloride) (PAH) is covalently immobilized onto titanium. The coating catalyzes NO generation from the endogenous S‐nitrosothiol GSNO, retains activity after multiple reuse cycles and pH exposures, and maintains endothelial cell viability while modulating ...
Siti Nur Asyura Adzlan   +7 more
wiley   +1 more source

Modulation of GSNOR activity for improved NO homeostasis and flood resilience in plants

open access: yesPlant Signaling & Behavior
Flood-induced hypoxia (low oxygen concentration) is increasing in frequency and intensity due to climate change, leading to significant crop yield losses and posing a major threat to global food security.
Thea Wulf   +2 more
doaj   +1 more source

Formation and biological role NO at an allergic inflammation

open access: yesБюллетень сибирской медицины, 2009
In the review ways and mechanisms of formation nitric oxide are considered. Effects metabolite nitric oxide in regulation of an allergic inflammation are analysed.
O. V. Kozina, L. M. Ogorodova
doaj   +1 more source

Semiconducting Polymer Nanoparticles Enable Light‐Controlled Bidirectional Modulation of Nitric Oxide in Endothelial Cells

open access: yesAdvanced Science, Volume 13, Issue 30, 28 May 2026.
Bimodal modulation of nitric oxide in endothelial cells is achieved by light‐sensitive polymer nanoparticles. In dark, P3HT/PEDOT:PSS NPs boost intracellular ·NO, upregulate both endothelial and induced nitric oxide synthase, and drive a metabolic shift toward glycolysis.
Camilla Marzuoli   +12 more
wiley   +1 more source

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