Results 61 to 70 of about 21,171,580 (198)

The reaction products of sulfide and S-nitrosoglutathione are potent vasorelaxants [PDF]

Nitric Oxide, 2015
The chemical interaction of sodium sulfide (Na2S) with the NO-donor S-nitrosoglutathione (GSNO) has been described to generate new reaction products, including polysulfides and nitrosopersulfide (SSNO(-)) via intermediacy of thionitrous acid (HSNO). The aim of the present work was to investigate the vascular effects of the longer-lived products of the ...
Berenyiova, Andrea, Grman, Marian, Mijuskovic, Ana, Stasko, Andrej, Misak, Anton, Nagy, Peter, Ondriasova, Elena, Cacanyiova, Sona, Brezova, Vlasta, Feelisch, Martin, Ondrias, Karol   +10 more
openaire   +5 more sources

Drug‐Free Thrombolysis Mediated by Physically Activated Micro/Nanoparticles

Advanced Functional Materials, Volume 36, Issue 34, 27 April 2026.
Overview of particle‐mediated thrombolytic effects (thermal, mechanical, and chemical) and their activating physical stimuli (light, ultrasound, and magnetic field) in drug‐free thrombolysis. ABSTRACT Thrombus‐associated disorders rank among the world's leading causes of death, with ischemic heart disease and stroke as the main contributors.
Pierre Sarfati, Yoann Lalatonne, Cédric Chauvierre   +2 more
wiley   +1 more source

Deployable 3D‐Printed Vascular Stent with Surface‐Catalysed Endogenous Nitric Oxide Generation

Advanced Materials, Volume 38, Issue 21, 13 April 2026.
A deployable 3D‐printed vascular stent was fabricated with surface‐catalyzed endogenous nitric oxide generation, representing a promising new direction for stent development. The stent can be remotely controlled by magnetic force in its compressed state and fully deployed at the target site using an untethered heat source, potentially eliminating the ...
Kun Zhou, Zifei Han, Kang Lin, Di Wu, Siti Nur Asyura Adzlan, Qingqing Fan, Christina Cortez‐Jugo, Rona Chandrawati, Cyrille Boyer   +8 more
wiley   +1 more source

Therapeutic Gases in Biomedicine: Updates on Nitric Oxide and Beyond

Advanced Science, Volume 13, Issue 23, 23 April 2026.
Therapeutic gases, including NO, CO, H2S, H2, CO2, O2, and Xe, play vital roles in cellular signaling and repair. This review highlights the emerging carriers and delivery systems that enable controlled, localized gas release for diagnostic and therapeutic applications.
Syed Muntazir Andrabi, Navatha Shree Sharma, Imran Ibn Gani Rather, S. M. Shatil Shahriar, Jingwei Xie   +4 more
wiley   +1 more source

S-nitrosoglutathione accelerates recovery from 5-fluorouracil-induced oral mucositis.

PLoS ONE, 2014
IntroductionMucositis induced by anti-neoplastic drugs is an important, dose-limiting and costly side-effect of cancer therapy.AimTo evaluate the effect of the topical application of S-nitrosoglutathione (GSNO), a nitric oxide donor, on 5-fluorouracil (5-
Maria Adriana Skeff, Gerly A C Brito, Marcelo G de Oliveira, Cintia M Braga, Matheus M Cavalcante, Victor Baldim, Rosenilde C Holanda-Afonso, Carina M Silva-Boghossian, Ana Paula Colombo, Ronaldo A Ribeiro, Vivaldo Moura-Neto, Renata F C Leitão   +11 more
doaj   +1 more source

Synergistic Intra‐ and Inter‐Nanozyme Electron Transfer through Interfacial Assembly for Enhanced Multi‐Enzyme Activity

Advanced Science, Volume 13, Issue 19, 2 April 2026.
A novel Prussian blue‐based composite nanoenzymes (PB C‐NZs)‐MoS2/PB, was designed based on the electron transfer mechanism and transport pathway. The structure uses MoS2 as the substrate, with PB grown on its surface through a surface assembly method.
Kun Lu, Jizi Liu, Xiaoyang Zhu, Yu Mao, Hongliang He, Pingqiang Cai, Yan Li, Ning Gu   +7 more
wiley   +1 more source

S-nitrosoglutathione reductase inhibition regulates allergen-induced lung inflammation and airway hyperreactivity. [PDF]

PLoS ONE, 2013
Allergic asthma is characterized by Th2 type inflammation, leading to airway hyperresponsivenes, mucus hypersecretion and tissue remodeling. S-Nitrosoglutathione reductase (GSNOR) is an alcohol dehydrogenase involved in the regulation of intracellular ...
Maria E Ferrini, Bryan J Simons, David J P Bassett, Matthews O Bradley, Kevan Roberts, Zeina Jaffar   +5 more
doaj   +1 more source

Altered plant and nodule development and protein S-nitrosylation in Lotus japonicus mutants deficient in S-nitrosoglutathione reductases.

Plant and Cell Physiology, 2019
Nitric oxide (NO) is a crucial signaling molecule that conveys its bioactivity mainly through protein S-nitrosylation. This is a reversible post-translational modification (PTM) that may affect protein function.
M. A. Matamoros, Maria C Cutrona, S. Wienkoop, J. Begara-Morales, N. Sandal, Irene Orera, J. B. Barroso, J. Stougaard, M. Becana   +8 more
semanticscholar   +1 more source

A Review of Vagus Nerve Stimulation for Disease: Comprehensive Theory and Evidence for Mechanisms of Action

Comprehensive Physiology, Volume 16, Issue 2, April 2026.
Vagus nerve stimulation (VNS) effects span central and peripheral organ systems through diverse mechanistic pathways. This comprehensive review provides a unified synthesis of these mechanisms across neurological, cardiovascular, immunological, metabolic, and gastrointestinal domains, filling a critical gap and serving as a foundational resource for ...
Yifeng Bu, Alex Liang, Benjamin U. Hoffman, Dawn M. Schiehser, Oliver Case, Alan Simmons, Ruth Klaming, Andres Gottfried‐Blackmore, Ravinder K. Mittal, Christopher Puleo, Hubert Lim, Imanuel Lerman   +11 more
wiley   +1 more source

The Metabolic Role of Mitochondria in the Perinatal Cardiac Development and Cardiovascular Diseases

Exploration, Volume 6, Issue 2, April 2026.
This review explores the critical role of mitochondria in heart development and cardiovascular disease. It highlights how mitochondrial maturation during embryonic‐to‐postnatal transition, regulated by oxygen and metabolic changes, shapes cardiac structure and function.
Minghao Li, Ruiyi Zhang, Xinyuan Li, Hefeng Huang   +3 more
wiley   +1 more source