Results 181 to 190 of about 21,351,086 (309)

EXOSC3 knockdown induces G1/S phase arrest to suppress hepatocellular carcinoma cell proliferation. [PDF]

Sci Rep
Chen YM, Huo YX, Wei WS, Liu YX, Wang SH, Jiang L, Rong-He, Zhang HL, Jiang LH.   +8 more
europepmc   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Phase-sensitive wavelength conversion based on cascaded quadratic processes in periodically poled lithium niobate waveguides

We propose and experimentally demonstrate a novel scheme of phase-sensitive wavelength conversion, based on a combination of cascaded second-order nonlinear effects in two cascaded periodically poled lithium niobate ...
Parmigiani, F., Slavík, R., Petropoulos, P., Richardson, D.J., Liu, S., Kakande, J., Lee, K.J.   +6 more
core  

Dissection of c-myc domains involved in S phase induction of NIH 3T3 fibroblasts

, 1994
The product of the c-myc proto-oncogene is an important regulator of cell proliferation and apoptosis in murine fibroblasts. Addition of the tumor promoter, phorbol myristate acetate (PMA), prevents apoptotic cell death induced by low serum ...
BRANCOLINI, Claudio, SCHNEIDER C, Gustincich, Stefano, BRANCOLINI C, LEE WMF, SCHNEIDER C., LEE W, GORUPPI S, GUSTINCICH S   +8 more
core  

S-phase PARylation of microprotein RSMC enhances the function of Sororin in sister chromatid cohesion. [PDF]

EMBO J
Jiang M, Zhang J, He J, Miao Y, Wang L, Zhong H, Gong Y, Li Z, Du LL, Xu X, Chen C, Ydyrys A, Xia Y, Cao Q, Lou H, Hou W.   +15 more
europepmc   +1 more source

Asymmetric distribution of parental H3K9me3 in S phase silences L1 elements. [PDF]

Nature, 2023
Li Z, Duan S, Hua X, Xu X, Li Y, Menolfi D, Zhou H, Lu C, Zha S, Goff SP, Zhang Z.   +10 more
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Influence of Post-Processing on S-Phase Formation During Plasma Nitriding of Additively Manufactured Inconel 939. [PDF]

Materials (Basel)
Maj P, Radziejewska J, Diduszko R, Marczak M, Nowicki R, Anna PL, Borowski T, Sitek R.   +7 more
europepmc   +1 more source

S-Phase Fraction [PDF]

, 2020
openaire   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source