Results 51 to 60 of about 21,351,086 (309)
Multisite Phosphorylation and the Countdown to S Phase [PDF]
Cell, 2001 Remarkably, SCF(Cdc4) ubiquitin ligase binds and ubiquitinates Sic1 decorated with six, but not five, phosphates. This numerical wizardry suggests how analog inputs can be rectified to digital outputs. Unraveling the counting mechanism promises to generate new insights into the architecture of protein nanoprocessors.Deshaies, Raymond J., Ferrell, James E.openaire +2 more sourcesVenous Thromboembolism in Pediatric Bone Sarcoma Patients: A 10‐Year, Single‐Institution Experience Encompassing the COVID‐19 Pandemic
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background
Osteosarcoma (OS) and Ewing sarcoma (EWS) are the most common primary bone cancers in children, but acute thrombosis is poorly characterized in this population. Our study evaluated the rates of venous thromboembolism (VTE) and associated risk factors in pediatric patients with bone sarcomas treated over a 10‐year period encompassing Sarah Kappa, Shou Xu, Mark Zobeck, Sarah E. Sartain, Nino Rainusso, Lisa Wang, Nicole Montgomery, Paige Wheaton, Sarah Whittle +8 morewiley +1 more sourceBurkitt′s lymphoma in leukemic phase in an Indian boy
Indian Journal of Dental Research, 2011 Burkitt′s lymphoma (BL) is the most common childhood cancer in Africa and is most prevalent in areas endemic for malaria. The disease, a malignant growth of lymphoid tissue, usually presents itself as a large tumor of the jaw.Vijeev Vasudevan, Usha Mohandas, V Manjunath +2 moredoaj +1 more sourceSerological Benefit of SARS‐CoV‐2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background
Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.Janna R. Shapiro, Freda Qi, Karen Colwill, Alina D. Dorogy, Ying Liu, Michelle Science, Anne‐Claude Gingras, James M. Rini, Sumit Gupta, Sarah Alexander, Shelly Bolotin, Tania H. Watts +11 morewiley +1 more sourceSafety, Tolerability, Pharmacokinetics, and Pharmacodynamics of the Novel Long‐Acting FGF21 Analog Zalfermin
Clinical and Translational ScienceThis first‐in‐human study investigated the safety, pharmacokinetics, and pharmacodynamics of the long‐acting fibroblast growth factor 21 (FGF21) analog zalfermin.Kirsten Dahl, Martin Haljeta Friedrichsen, Rasmus Ribel‐Madsen, Jakob Schiøler Hansen, Jesper Ole Clausen, Mads Axelsen, Mads Sundby Palle, Solvej Lund Lippert, Olle Björkdahl, Søren Toubro, Cassandra Key, Birgitte Andersen +11 moredoaj +1 more sourceCyclin Regulation by the S Phase Checkpoint [PDF]
Journal of Biological Chemistry, 2010 In eukaryotic cells a surveillance mechanism, the S phase checkpoint, detects and responds to DNA damage and replication stress, protecting DNA replication and arresting cell cycle progression. We show here that the S phase cyclins Clb5 and Clb6 are regulated in response to genotoxic stress in the budding yeast Saccharomyces cerevisiae.Gloria, Palou, Roger, Palou, Angel, Guerra-Moreno, Alba, Duch, Anna, Travesa, David G, Quintana +5 moreopenaire +2 more sourcesDeep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background
An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...Sofie Johansson Alm, Bea Tornberg, Erik Delsing Malmberg, Henrik Hasle, Kristian Løvvik Juul‐Dam, Lars Palmqvist, Borhan R. Saeed, Giti Shah Barkhordar, Anastasia Soboli, Anna Staffas, Jonas Abrahamsson, Linda Fogelstrand +11 morewiley +1 more sourceMeasurement of the CP-violating phase \phi s in Bs->J/\psi\pi+\pi- decays [PDF]
, 2012 Measurement of the mixing-induced CP-violating phase phi_s in Bs decays is of prime importance in probing new physics. Here 7421 +/- 105 signal events from the dominantly CP-odd final state J/\psi pi+ pi- are selected in 1/fb of pp collision data ...Minard, M, van den Brand, J, O. Deschamps, J. Closier, Reid, M M, J. P. Lees, Mylroie-Smith, J., Asamar, E, Meissner, M, dos Reis, AC, Gao, Y., M. Gandelman, Wiggers, L, Yang, Z., Diaz RG, Lees, J.-P., Gys, T, Vecchi, S, A. Dosil Suárez, Barlow, R. J., Korolev M, De Miranda JM, Bedeschi, F., Satriano C, Gaspar C, Okhrimenko, O., P. Krokovny, C. Pavel Nicorescu, Bencivenni G, Abellan Beteta, C., Pugatch, V., F. Machefert, Clarke, PEL, G. Polok, Ketel, T., Mous, I, Ekelhof, R., Ferro-Luzzi, M., I. Sepp, Tisserand, V, Lefèvre, R., Zangoli, M, Golubkov, D., Koopman, RF, Lieng, M, Vidal, X, Lai, A., Jawahery, A., Bozzi, C., van den Brand, J., Perret, P, Cliff, HV, Fontana, M., Couturier, B, Cenci, R., Needham, M, Koopman, R., Wishahi, J, Smith, E., Barter W, Gibson, V., K. Senderowska, Pie Valls, B., Kim, Y.M., Back, J, H. Schindler, Soomro, F., Blouw, J, Golubkov D, Patrick, G, E. L. Asamar, Milanes, D, Webber, A.D., Lacarrere D, Muller K, D. Gascon, P. Koppenburg, Swientek, S, de Bruyn K, Baldini, W., Mac Raighne, A, Hussein, M, B. Pie Valls, Nguyen-Mau, C., Plackett, R., Bailey DS, Decamp, D., Lambert, R, T. Nikodem, Seyfert P, S. C. Haines, M. Merk, Gioi LL, Perego, D, Niess V, La Thi, V.N., A. Grecu, David, PNY, Cadeddu, S., Appleby, R, N. Sagidova, Morda, A., De Paula L, Voong, D., K. Holubyev, Wiedner, D., Bocci Valerio, Coco V, P. F. Harrison, Auriemma, G., Huston, R.S., Savrina D, Johnson, D, Gallas Torreira, A, Smith AC, F. Jansen, Comerma-Montells, A, Muster, B., Gobel C, Rakotomiaramanana, B., Gordon, H., Maev O, G. Ciezarek, Appleby, RB, Donleavy, S, R. Märki, D. Popov, Couturier B, Burducea I, E. Lopez Asamar, C. Blanks, P. Hopchev, Imong, J, Johnson D, M. P. Casasus, Patel, GD, Cardini, A, E. Jans, A. Borgia, Barlow, RJ, Pal, B., H. Ruiz, Ghez, P., Giani', S., Skwarnicki T, Marks J, Wilson, F, Gambetta, S., K. Sobczak, Vazquez Regueiro, P, Malde, S, PALANO, Antimo, Corti, G., Mazurov Alexander, Lopes, J. H., A. P. Alvarez, J. Merkel, Muryn, B., Sepp I, Romero, D. A. Roa, C. Abellan Beteta, Bettler, M.-O., Amato S, Valenti, G., Ward, D.R., Schmidt, B., Lopez-March N, Francisco O, Li, Y., Gutierrez OA, Polok, G., Zhang, Y., M. Calvi, Garnier, J-C, Liu, B., Harrison, J, Williams, M. P., Kenyon, I. R., Volyanskyy, D., Kreps, M., Contu, A, Kruse, F, Harrison, P, Polci, F., Skwarnicki, T., E. Perez Trigo, Lazzeroni, C, Aaij R, Senderowska K, Ghez, Ph, V. Gibson, F. D. Bonal, Pilar T, C. J. Parkinson, Jansen, F, E. Aslanides, D. Lacarrere, Cauet C, Elsasser, C, Huse T, van Tilburg, J., C. Hadjivasiliou, Kerzel, U., Arrabito L, Rosello M, Silva Coutinho, R, S. Borghi, Zhang, WC, Mamunur, R, Patel, M., J. J. Saborido Silva, Burducea, I, Calabrese, R., J. Garra Tico, Calvi M, P. Jaton, Sapunov, M., Fontanelli, F, Elsasser C, Malde S, Karacson M, Bauer, Th, Oblakowska Mucha, A., Xie, Y, Albrecht J, Uwer, U, A. Bien, C. Cauet, Gallas Torreira, A., Schlupp, M., Liles, M., M. Alexander, L. Li, Lambert, D, Bursche, A, Szczekowski, M, Ruiz, H, T. Shears, Currie, R, J. A. H., Schneider O, Velthuis, J, Britsch, M, Wyllie, K., Pilař, T., R. Ekelhof, Ferro Luzzi, M, Burducea, I., I. Bediaga, Cliff, H V, Casasus MP, D. L. Perego, Orlandea, M., T. Nakada, Palutan M, Hussein, M. Jahjah, Mccarthy, J., Owen, P., Y. Gao, F. Maciuc, Sepp, I, Goicochea JMO, Suarez, A, V. Bocci, Bettler, M -O, Beaucourt, L., Serra, N., Pazos Alvarez, A., Dordei, F., N. Neufeld, Stone, Sheldon L., Belogurov S, Campana Pierluigi, A. Kozlinskiy, J. Magnin, Camboni, A., Kreps M, Bocci, V., Contu, A., T. Brambach, A. Powell, Bauer, T., Lacarrere, D., M. D. Cian, Elsby D, Cliff, H, Z. Ajaltouni, Buechler-Germann A, Rademacker, J.H., Santos DM, Muheim F, Parkinson, C, Ajaltouni, Z, Ogilvy S, V. N. L., Ogilvy, S, Lopez Asamar E, Coutinho, R. Silva, Tsaregorodtsev, A., Mueller, K, Muheim, F., Thi, V, A. C. dos Reis, Borsato, M., Cardinale Roberta, Greening E, Hansmann-Menzemer, S., J. He, Polycarpo, E, J. van den Brand, Richards A, Papanestis, A., Bates A, Liu, G., Egede, U., Jost, B., Mylroie-Smith, J, Cheung, S. -F., Affolder, A, Semennikov A, Lefrançois, J., Redford, S., Picatoste Olloqui E, Haefeli, G, Shatalov, P., Subbiah, V, L. A. Granado Cardoso, Massafferri, A., Diniz Batista, P., Dettori F, Witzeling, W, P. D. Simone, Topp-Joergensen, S., Marks, J., Prisciandaro, J, M. Adinolfi, Jaton, P, Martín Sánchez, A, A. Dziurda, Patrick, GN, Merk, M, Popov, D, Mcskelly, B., Harrison J, Gershon T, Luisier, J, C. Frei, G. D. Patel, S. Filippov, Henrard, P, Bien A, Beteta CA, Mac Raighne, A., Mountain, R, Mamunur RMD, P. Perret, G. Sabatino, Whitehead, M, Cardoso LAG, Matveev, M., Krocker, G., M. Korolev, Blusk, S., F. J. P. Soler, Kim, YM, Gauvin, N, Sannino, M., Fernandez Albor, V., John M, Sabatino G, Cliff, H. V., Regueiro, P, P. Collins, R. Silva Coutinho, Knecht, M., Schune, M. H., Nguyen, A.D., Szumlak, T, D. Derkach, Powell, A., Rodriguez Perez P, E. Hicks, Cunliffe, S., A. Martín Sánchez, S. Ali, Shires, A, A. Nomerotski, Wandernoth, S, Saborido Silva, JJ, Alvarez, A, Dovbnya, A., M. Orlandea, Huse, T, P. Ghez, Schneider, O, De Capua, S., Soler, F.J.P., Martellotti Giuseppe, K. Hennessy, Wilson, FF, Bettler, M. O., Fitzpatrick, C, M. Meissner, Rinnert, K., E. P. Trigo, T. Blake, Bizzeti Andrea, Pal, B K, Leroy O, A. Gomes, M. Patel, Pellegrino A, Latham T, A. D. Suarez, V. Obraztsov, Parkinson, CJ, Savrie, M, Parkinson, C J, G. Lanfranchi, Artuso M, Maratas, J., Bay A, Sparkes, A., R. Oldeman, Patel, G. D., R. Le Gac, Alvarez Cartelle, P, Gaspar, C, P. M. Bjornstad, Wiggers, L., Hall, S., Magnin, J, Schune, M -H, Coquereau, S., Pellegrino, A, B. Adeva, Hernando Morata, J. A., Gruenberg, O., Williams, M, Faerber, C, Martinelli M, Fitzpatrick C, Keaveney J, Perret, Pascal, Niet, R., Meadows, B., Haen, C, W. Qian, Savrina, D., Koppenburg P, Wandernoth, S., Martellotti G, Aslanides, E, Bowen, E., Benson S, Websdale, D, Hopchev P, Von Loeben Jorg Horst Jochen, J. Buytaert, Bowcock, TJV, Li Gioi, L, Hunt P, Keune A, Manca Giulia, Golutvin, A, Satriano Celestina, Back, J.J., De Bonis, I., Rosello, M, Collins, P., M. Matveev, Linn C, Hill, D., Mazurov, A., Ciezarek G, J. A. Hernando Morata, Buechler-Germann, A., R. Cardinale, Farber C, Graugés, E, J. v. Loeben, Hombach, C., B. Couturier, Bettler MO, Mangiafave, N., B. Saitta, R. Plackett, van Leerdam, J., van den Brand J, Dzhelyadin, R., Silva Coutinho, R., Iakovenko, V, Leflat, A, Brown, H, R. Schwemmer, Keune, A., Kreplin, K, Raven, H.G., Kruse, F., Minard, M-N, Playfer, S., Gandelman, M., A. Shires, Rouvinet, J, Blanks C, Smith NA, Nikodem, T, Del Buono L, P. De Simone, G. Lafferty, Shapoval I, Rangel, M. S., Derkach Denis, Thomas, E, Grauges E, Raven G, Thomas, C, A. Puig Navarro, A. Camboni, A. C. dos, Krocker G, D. Savrina, DʼAmbrosio, C., Nikitin, N., Blanks, C., Gligorov, V V, Poluektov A, Palano, A, W. Bonivento, Ciezarek, G., T. Pilař, X. Cid Vidal, P. Diniz Batista, D. Johnson, Oyanguren, A., Whitehead, M. (Mark), Palutan Matteo, Gordon, H, Keaveney, J, Deplano Caterina, Borghi S, Mathe, Z., Henrard, Pierre, Sanchez, AM, Pérez Calero Yzquierdo, A., M. Ferro Luzzi, D'Ambrosio, C, Buytaert J, Polok, G, Idzik, M., Skwarnicki, T, Kudryavtsev V, Bediaga I, Bien, A., Cowan, G, A. Keune, Stagni, F., Barlow RJ, Sarti, A, Schune, M.-H., G. Carboni, H. Lu, B. Muryn, Wilson, F.F., C. Göbel, Machefert, F, Garrido L, Mueller K, T. Gys, Brook, N H, Brambach T, Spaan, B, V. Coco, De Capua S, Donleavy S, Britsch M, Eitschberger, U., Korolev, M, Lieng M, Roa Romero, D A, Lupton, O., Puig Navarro, A., A. Poluektov, Perazzini, S., Eisele, F, Albor, V, Gys, T., van Herwijnen, E, Alkhazov, G, Tico, J. Garra, F. Fontanelli, K. Müller, Kvaratskheliya T, T. Gershon, A. P. C., Alves, A, Maerki, R., C. Santamarina Rios, Lambert, R W, Oldeman, R, Paterson, SK, Jones, CR, Veltri, M., van Tilburg, J, Hartmann, T, G. Casse, Collaboration, L, D. Hutchcroft, G. Passaleva, Eklund L, Lopez Asamar, E., Semennikov, A, Benayoun, M., Robbe, P., Barsuk, S, R. S. Coutinho, Frank, M, Vollhardt, A, Kaballo, M., Jones CR, A. Pazos Alvarez, M. Shapkin, Latham, T, Li, L., Fave, V, Maynard, B, Cid Vidal, X, Pescatore, L., Pessina, G, Closier J, A. Sarti, Auriemma G, Aquines Gutierrez, O., Panman, J., Martin, L, Sannino, M, Eidelman S, Naik P, Mamunur, RMD, Albrecht, J, Fiorini, M., Lambert, R.W., Bachmann, S, Mussini, M., S. Bachmann, Teodorescu, E, J. Keaveney, Galli D, T. Kvaratskheliya, Mountain, R., Pavel-Nicorescu, C, Raniuk I, Schiller, M, Tico JG, L. D. Buono, H. V. Cliff, M. Knecht, Gushchin, E., M. Perrin Terrin, Pereira, D, Coca, C., Sanchez, A, Lopez March, N., Vorobyev, A., Bien, A, T. Lesiak, Rinnert, K, Bjornstad, P, Lafferty, G, Langenbruch C, Borghi, S., Haines, S, E. Santovetti, Voss, H., van Beuzekom, M., Adinolfi, M, J. H. Lopes, Y. Amhis, N. Bondar, B. Schmidt, Belogurov, S., Lionetto, F., Witek, M, Barlow, R.J., J. Garofoli, J. Imong, Lefrancois J, Savrie M, I. Raniuk, M. Kucharczyk, Campana P, Brook, NH, Corti G, Kucharczyk M, Grecu A, A. Artamonov, Fernandez Albor, V, Harji, R, Satriano, C., Ferreira Rodrigues, F., Jurik, N., Rogers GJ, Rangel, M.S., Xing, F, Pepe Altarelli, M., Shevchenko, V, Hicheur, A., T.h. Bauer, Rodrigues F, Wang, J., Shevchenko, O, Dovbnya A, A. Bobrov, B. Gui, Xing, Z, P. Henrard, Dreimanis, K., I. Mous, Degaudenzi, H, Gregson S, Ilten, P., Moran, D., B. Sciascia, Lanfranchi, G., Battista, V., Gao, Y, M. Frosini, van Eijk, D, Barlow, R, Jans, E., Batista PD, Pazos Alvarez A, Oblakowska Mucha, A, Kucewicz, W., Mueller, K., Nikitin, N, Bondar A, Rodrigues E, Maurice, E, Nasteva, I, Monteil, S, A. Carbone, Torr, N., Puig Navarro A, Oldeman, R., Manca G, Shevchenko, V., Gomes A, R. Harji, Joram, C., A. Papanestis, Sciubba, A., De Simone P, G. Haefeli, I. R. Kenyon, Easo, S, De Lorenzi F, Karbach, T.M., Egorychev, V., Marchand, J. F., Santovetti E, Kerzel U, Wiedner, D, Jones, C.R., Santamarina Rios, C, K. C. Akiba, Seco M, Hulsbergen W, Manca, G, Machikhiliyan, I.V., Dickens, J., Alkhazov G, Valls BP, Volyanskyy, D, Altarelli, M. Pepe, I. V. Machikhiliyan, A. Pellegrino, G. Penso, Paterson, S.K., Reid, MM, J. Bressieux, Bowcock, T, W. Barter, Cauet, C, C. Lazzeroni, Plo Casasus, M, Vidal, X. Cid, Leroy, O., Pesen, E., Pepe Altarelli, M, Otalora Goicochea, J. M., Knecht, M, Barschel, C, Ciezarek, G, T. Hartmann, Abellán Beteta, C, Gomez MC, G. Auriemma, Obraztsov, V, Rodrigues, E., Aquines Gutierrez, O, P. R. Perez, Alvarez Cartelle P, Brodzicka, J., Hadjivasiliou C, Cowan, G. A., Otalora Goicochea JM, Pinci D, Ruf, T., Hennessy K, D. Esperante Pereira, Garrido, L, E. Maurice, D. A. R., E. Greening, De Capua, S, Heijne, V, Merkel, J, Niess, V, Papanestis, A, He, J., Cogan, J., Neri, N., Bursche A, N. Serra, S. Ogilvy, A. Novoselov, Gersabeck, M., Bondar N, Shekhtman, L, Lai A, N. A. Smith, Smith, N.A., Cartelle, P, Shears, T, Krokovny, P, Andrews, J. E., Tran, M.T., David P, Calvo Gomez, M, J. Albrecht, David R, Grecu, A, Mamunur, R. M. D., Eklund, L, Minard, M -N, Furcas Sara, Nandakumar, R, Hicks, E., Ferro-Luzzi, M, Gauld, R., Popovici, B, H. Gordon, T. Skwarnicki, V. Fave, P. Robbe, MacRaighne, A., Filippov S, M. Liles, O. Okhrimenko, M. P. Altarelli, K. Rinnert, Santacesaria R, Carvalho Akiba K, Mac Raighne A, Lefevre R, B. Maynard, G. Alkhazov, Teodorescu, E., Rodrigues, F., Büchler-Germann, A, Naik, P., Pellegrino, A., Liu B, Schaack, P, Calvi, M, Liu G, Pal, B, D. Pinci, Viaud, B, Cardoso, LAG, Barsuk, S., Casse, G., Lanfranchi G, Molina Rodriguez, J., P. M. Bjørnstad, Ajaltouni, Z., Salzmann C, Graziani, G, M. S. Rangel, Stone, S., Bocci, V, Brook, N, Muresan R, A. Richards, Frosini, M., Obraztsov V, Garra Tico, J., Martin, L., Bondar, A, Pavel Nicorescu, C., Uwer, U., Greening, E., Camboni, A, Deplano, C, F. Eisele, Degaudenzi, H., Contu A, Cook A, Oblakowska-Mucha A, Prouve, C., Carbone Angelo, P.h. Ghez, Bjornstad, P. M., Schmelling M, Stahl, S., Bettler, M. -O., Linn, C., O. Shevchenko, Martinelli, M., A. Cook, Constantin F, Vazquez Gomez, R, Chiapolini N, Bonivento Walter, Blanc, F., Lopes, J, Garofoli, J., Roiser, S, M. Nicol, R. David, Adinolfi, M., Schopper, A., C. D'Ambrosio, Okhrimenko, O, La Thi, V N, D. E. Pereira, Firlej, M., Palutan, M, S. Miglioranzi, Paterson, S K, M. J. Hussein, Fontanelli F, Marki R, M. Clemencic, Penso G, A. Massafferri, Hampson T, Clarke, P. E L, Molina Rodriguez, J, Gallas Torreira A, Belyaev, I, A. Martens, Olloqui, E, Kruzelecki K, Farinelli C, Gascon, D, M. Karacson, Greening, E, Satta, A., Henry, L., Playfer, S, Comerma Montells, A., Palano, A., Head, T., A. Bursche, Rademacker, J, Adrover, C., Appleby, R B, Ferro-Luzzi M, Lees, J, C. Patrignani, C. A. Beteta, Raniuk, I., Iakovenko V, Hampson, T., Schmelling, M, Harnew N, Couturier, B., Kim, Y, Visniakov, J., Straumann, U., R. J. Barlow, G. Manca, T. Huse, dos Reis AC, Artuso, M., Aaij, R, B. Pal, Perrin-Terrin, M, Mous I, Parkinson, C.J., Kenyon, I R, Gao Y, Gershon, T. J., Topp-Joergensen, S, Appleby, R. B., Bediaga, I., Bird, T., Jaeger A +999 morecore +1 more source
