Results 81 to 90 of about 309,430 (247)

Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy

Advanced Healthcare Materials, EarlyView.
Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima, Sarmila Majumder, Divya S. Patel, Chunyu Hu, Hong Li, Xin Huang, Kim Truc Nguyen, Jacob Doon‐Ralls, Chiranth K. Nagaraj, Mangesh D. Hade, Setty M. Magaña, Eswar Shankar, Xiaoli Zhang, Daniel G. Stover, Bhuvaneswari Ramaswamy, Eduardo Reátegui   +15 more
wiley   +1 more source

Identification and Characterization of S-RNases in Japanese Plum Genotypes

Journal of Agricultural Science, 2019
Many species of the genus Prunus exhibit the gametophytic self-incompatibility system, governed by the S-locus, that encode S-Ribonucleases in the pistil, and are able to degrade the RNA of the pollen tubes when the S-haplotypes of both gametophytes are the same, preventing the fertilization of the oosphere.
Rauny O. de Souza, Marco A. Dalbó, Eugenia J. B. Braga, Valmor J. Bianchi   +3 more
openaire   +2 more sources

Packed for Ossification: High‐Density Bioprinting of hPDC Spheroids in HAMA Toward Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
Human periosteum‐derived cell spheroids bioprinted at high density within a hyaluronic acid matrix promote fusion and hypertrophic cartilage formation in vitro. Early encapsulation enhances spheroid interaction and matrix maturation, generating scalable cartilage templates intended for endochondral bone regeneration.
Ane Albillos Sanchez, Maria Paula Marks, Paula Casademunt, Adrián Seijas‐Gamardo, Ioannis Papantoniou, Lorenzo Moroni, Carlos Mota   +6 more
wiley   +1 more source

Examining the Protein Interactome and Subcellular Localization of RNase J2 Complexes in Streptococcus mutans

Frontiers in Microbiology, 2019
Regulated RNA turnover is vital for the control of gene expression in all cellular life. In Escherichia coli, this process is largely controlled by a stable degradosome complex containing RNase E and a variety of additional enzymes.
Rong Mu, Pushkar Shinde, Zhengzhong Zou, Jens Kreth, Jens Kreth, Justin Merritt, Justin Merritt   +6 more
doaj   +1 more source

Tracking Spatiotemporal Extracellular Matrix Evolution and Tissue Fusion in 3D Microtissues via Click Chemistry‐Based Metabolic Labelling

Advanced Healthcare Materials, EarlyView.
Metabolic labeling of nascent proteins in 3D microtissue spheroids provides a powerful analytical approach for large‐scale tissue engineering. Incorporation of non‐canonical amino acids with fluorescent tagging enables spatiotemporal investigation of extracellular matrix deposition and its evolution during multicellular tissue development and fusion ...
Theresa Koenig, F. Max Yavitt, Laura Veenendaal, Tim B. F. Woodfield   +3 more
wiley   +1 more source

Natural Biomaterials for Osteochondral Repair: From Source to Strategy

Advanced Healthcare Materials, EarlyView.
Biological origin‐guided overview of natural biomaterials and therapeutic strategies for osteochondral tissue engineering. The circular diagram categorizes representative materials and strategies into plant/algae‐derived, microbial‐derived, animal‐derived, and human‐derived sources, centered on an osteochondral defect repair model.
Hengyu Liu, Hanyang Zhang, Wenbo Yang, Hao Chen, Jincheng Wang, Fei Chang   +5 more
wiley   +1 more source

Determination of S-alleles in Iranian sour cherry (Prunus cerasus) using consensus primers [PDF]

Journal of Agricultural Sciences (Belgrade)
Sour cherry is a tetraploid species, and gametophytic self-incompatibility (SI) operates in this species in the same way as in other stone fruit trees. However, while self-compatibility is most common in sour cherry and self-compatibility (SC) genotypes ...
Nazari Samad A., Hajilou Jafar, Zeinalabedini Mehrshad, Imani Ali   +3 more
doaj   +1 more source

Viral Infection‐Inspired Autonomous Detection of Fusion‐Competent Viruses for Screening and Environmental Surveillance

Advanced Materials, EarlyView.
Inspired by viral entry mechanisms, the FUSION assay enables autonomous detection of respiratory viruses via membrane fusion–triggered CRISPR‐Cas13a activation. VEACON selectively fuses with fusion‐competent viruses, triggering fluorescence within confined vesicles.
Jae Chul Park, Yidam Song, Hyun‐Woo Choi, Jaeuk Sung, Harin Jin, WonSeok Gwak, Kirim Yoo, Soohwang Lee, Jongeon Park, Jeongmin Kim, Hye‐Jun Jo, Jahyun Koo, Youngdo Jeong, Kwan Hyi Lee, Seung‐Jung Kee, Hojun Kim   +15 more
wiley   +1 more source

Identification of S-RNase Genotypes of 65 Almond [Prunus dulcis (Mill.) D.A. Webb] Germplasm Resources and Close Relatives

Horticulturae
Self-incompatibility (SI) systems in plants prevent self-pollination and mating among relatives, enhancing genetic diversity in nature but posing challenges in almond production and breeding.
Panyun Xu, Lirong Wang, Xinwei Wang, Yeting Xu, Yarmuhammat Ablitip, Chunmiao Guo, Mubarek Ayup   +6 more
doaj   +1 more source

Identification and characterization ofS-RNasegenes in apple rootstock and the diversity ofS-RNasesinMalusspecies

Journal of Plant Biotechnology, 2016
We isolated and confirmed two S-RNases, denoted as mpS1 and mpS2, from apple rootstock ``Marubakaido`` (Malus prunifolia Borkh. Var. ringo Asami). These S-RNases contained and conserved five cysteine residues and two histidine residues, which are essential for RNase activity.
Hoy-Taek Kim, Shigeki Moriya, Kazuma Okada, Kazuyuki Abe, Jong-In Park, Toshiya Yamamoto, Ill-Sup Nou   +6 more
openaire   +2 more sources