Results 161 to 170 of about 21,319,883 (205)

Extracellular association and cytoplasmic partitioning of the IpaB and IpaC invasins of S. flexneri

Cell, 1994
Shigella species cause bacillary dysentery in humans by invading colonic epithelial cells. IpaB and IpaC, two major invasins of these pathogens, are secreted into the extracellular milieu. We show here that IpaB and IpaC form a complex in the extracellular medium and that each binds independently to a 17 kDa polypeptide, IpgC, in the bacterial ...
R, Ménard, P, Sansonetti, C, Parsot, T, Vasselon   +3 more
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Evaluation of culture media for enrichment and isolation of Shigella sonnei and S. flexneri

International Journal of Food Microbiology, 2001
The performance of Gram-negative (GN) broth with (10 microg/ml) and without novobiocin, Shigella broth (SB) with 0.5 and 3.0 microg/ml novobiocin, all incubated at 37 degrees C (SB with 3.0 microg/ml novobiocin also at 42 degrees C) and buffered brilliant green bile glucose (EE) broth with 1.0 microg/ml novobiocin incubated at 37 and 42 degrees C were ...
M, Uyttendaele, C F, Bagamboula, E, De Smet, S, Van Wilder, J, Debevere   +4 more
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O-antigen structure of Shigella flexneri serotype Yv and effect of the lpt-O gene variation on phosphoethanolamine modification of S. flexneri O-antigens

Glycobiology, 2013
Shigella flexneri is the major human pathogen causing shigellosis. O-antigens of all S. flexneri serotypes (except for serotype 6) share the →2)-α-l-Rhap(III)-(1 → 2)-α-l-Rhap(II)-(1 → 3)-α-l-Rhap(I)-(1 → 3)-β-d-GlcpNAc-(1→ basic O-unit, whereas differences between the serotypes are conferred by phage-encoded glucosylation and/or O-acetylation at ...
Yuriy A, Knirel, Ruiting, Lan, Sof'ya N, Senchenkova, Jianping, Wang, Alexander S, Shashkov, Yan, Wang, Andrei V, Perepelov, Yanwen, Xiong, Jianguo, Xu, Qiangzheng, Sun   +9 more
openaire   +2 more sources

In silico and in vivo approaches to recombinant multi-epitope immunogen of GroEL provides efficient cross protection against S. Typhimurium, S. flexneri, and S. dysenteriae

Molecular Immunology, 2022
Stress or Heat Shock Proteins (HSPs) have been included in various operations like protein folding, autophagy, and apoptosis. HSP families recognize as protective antigens in a wide range of bacteria because they have been conserved through evolution.
Hassan, Ardestani, Shahram, Nazarian, Abbas, Hajizadeh, Davoud, Sadeghi, Emad, Kordbacheh   +4 more
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Myosin light chain kinase plays an essential role in S. flexneri dissemination

Journal of Cell Science, 2000
ABSTRACT Shigella flexneri, the causitive agent of bacillary dysentery, has been shown to disseminate in colonic epithelial cells via protrusions that extend from infected cells and are endocytosed by adjacent cells. This phenomenon occurs in the region of the eukaryotic cell’s adherens junctions and is inhibited by pharmacological ...
M, Rathman, P, de Lanerolle, H, Ohayon, P, Gounon, P, Sansonetti   +4 more
openaire   +2 more sources

Structural elucidation of the O-antigen of the Shigella flexneri provisional serotype 88-893: structural and serological similarities with S. flexneri provisional serotype Y394 (1c)

Carbohydrate Research, 2011
The structure of the repeating unit of the O-antigen polysaccharide from Shigella flexneri provisional serotype 88-893 has been determined. (1)H and (13)C NMR spectroscopy as well as 2D NMR experiments were employed to elucidate the structure. The carbohydrate part of the hexasaccharide repeating unit is identical to the previously elucidated structure
R A, Foster, N I A, Carlin, M, Majcher, H, Tabor, L-K, Ng, G, Widmalm   +5 more
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[Gena types of Shigella enterotoxins of S. flexneri 2a].

Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi, 2004
To identify homogenous clones of S. flexneri 2a, using gene distribution polymorphism of Shigella enterotoxin 1 (set 1) and Shigella enterotoxin 2 (set 2) in a Shigellosis outbreak caused by S. flexneri 2a.In addition to field epidemiological investigation, 43 strains of S.
S, Bai, X, Li, G, Xia, H, Yuan, W, Zheng, H, Wang   +5 more
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Experimental keratoconjunctivitis caused by S. flexneri and by its genetic recombinations

Bulletin of Experimental Biology and Medicine, 1964
The presence of pathogenic properties was studied in 50 strains of S. flexneri 5 E. coli cultures and 267 sexual recombination by infection of the guinea pig conjunctiva. As noted, 20 strains of S. flexneri and 39 hybrids induced specific keratoconjunctivitis. Although S.
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Genotypic and phenotypic characterization of an aroD deletion-attenuated Escherichia coli K12-Shigella flexneri hybrid vaccine expressing S. flexneri 2a somatic antigen

Vaccine, 1992
The construction and characterization of EcSf2a-2, an aroD-deleted Escherichia coli-Shigella hybrid vaccine carrying chromosomal and plasmid genes from Shigella flexneri and expressing S. flexneri 2a somatic antigen in association with E. coli K12 core are described.
J W, Newland, T L, Hale, S B, Formal
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Development and evaluation of a Shigella flexneri 2a and S. sonnei bivalent invasin complex (Invaplex) vaccine

Vaccine, 2006
Over 160 million cases of shigellosis occur annually worldwide, with the two most prevalent species being Shigella flexneri and S. sonnei. Protective immunity against Shigella infection is primarily directed at the lipopolysaccharide (LPS) of the homologous serotype, so it may be necessary to combine monovalent vaccines for multiple Shigella serotypes ...
Edwin V, Oaks, K Ross, Turbyfill
openaire   +2 more sources