Bacteriophage Sf6 Tailspike Protein for Detection of Shigella flexneri Pathogens [PDF]
International audienceBacteriophage research is gaining more importance due to increasing antibiotic resistance. However, for treatment with bacteriophages, diagnostics have to be improved.
Mulard, Laurence, S +17 more
core +1 more source
Expression of Shigella dysenteriae serotype 1 O-antigenic polysaccharide by Shigella flexneri aroD vaccine candidates and different S. flexneri serotypes [PDF]
The potential utility of Shigella flexneri aroD vaccine candidates for the development of bi- or multivalent vaccines has been explored by the introduction of the genetic determinants rfp and rfb for heterologous O antigen polysaccharide from Shigella dysenteriae serotype 1.
I C, Fält +6 more
openaire +2 more sources
Amplifying the innate immune response : cell-cell propagation of proinflammatory signals during bacterial infection [PDF]
The enteroinvasive bacterium Shigella flexneri uses multiple secreted effector proteins to downregulate interleukin-8 (IL-8) expression in infected epithelial cells. Nevertheless, massive IL-8 secretion is observed in shigellosis. In this thesis, a novel
Kasper, Christoph Alexander
core +1 more source
Shigella Flexneri Serotypes: O-antigen Structure, Serotype Conversion, and Serotyping Methods
Shigella flexneri is the most common cause of shigellosis in developing countries. Up to now, 23 serotypes of S. flexneri have been reported. Different serotypes result from the addition of acetyl, glucosyl, or phosphatidylethanolamine groups on the O ...
Mehrzad Sadredinamin +4 more
doaj +1 more source
Interactions Between Shigella flexneri and the Autophagy Machinery [PDF]
Autophagy, an intracellular degradation process, is increasingly recognized as having important roles in host defense. Interactions between Shigella flexneri and the autophagy machinery were first discovered in 2005.
Krokowski, S, Mostowy, S
core +1 more source
ObjectiveThe aims of this study were to describe azithromycin (AZM) susceptibility patterns among Shigella isolates in Anhui, China and identify predictors of resistance with mobile element-mediated genes.MethodsA total of 517 non-duplicate Shigella ...
Yanyan Liu +16 more
doaj +1 more source
Phenotype microarray comparison between S. flexneri 2a 1363 against S. flexneri 2a YSH6000.
Phenotype microarray comparison between S. flexneri 2a 1363 against S. flexneri 2a YSH6000.
Tania Henríquez (3467492) +5 more
core +1 more source
tmRNA is essential in Shigella flexneri. [PDF]
Nonstop mRNAs pose a challenge for bacteria, because translation cannot terminate efficiently without a stop codon. The trans-translation pathway resolves nonstop translation complexes by removing the nonstop mRNA, the incomplete protein, and the stalled
Kenneth C. Keiler +7 more
core +1 more source
Characterization of S. flexneri DegP [PDF]
textShigella are Gram-negative facultative intracellular pathogens that cause bacillary dysentery. An important aspect of Shigella pathogenesis is the ability of the bacteria to invade intestinal epithelial cells, multiply within the eukaryotic cell ...
Purdy, Georgiana Elizabeth
core +1 more source
A Pentavalent Shigella flexneri LPS-Based Vaccine Candidate Is Safe and Immunogenic in Animal Models
A multivalent vaccine is much needed to achieve protection against predominant Shigella serotypes. Recently, we demonstrated the clinical applicability and immunogenic potential of tri-acylated S. flexneri 2a lipopolysaccharide (Ac3-S-LPS).
Vladimir A. Ledov +5 more
doaj +1 more source

