Shigella flexneri remodeling and consumption of host lipids during infection
, 2023 Shigella flexneri is a major cause of bacillary dysentery in the developing world, predominantly affecting the pediatric age group, with malnutrition being a common co-morbidity.
Wilson, D.W. +13 more
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Shigella hijacks the exocyst to cluster macropinosomes for efficient vacuolar escape.
PLoS Pathogens, 2020 Shigella flexneri invades host cells by entering within a bacteria-containing vacuole (BCV). In order to establish its niche in the host cytosol, the bacterium ruptures its BCV. Contacts between S.
Yuen-Yan Chang +8 more
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The epidemiology of S. sonnei and S. flexneri in Pima County, Arizona: an exploratory study. [PDF]
American Journal of Public Health, 1988 Investigation of 189 cases of shigellosis reported to the Pima County, Arizona Health Department in 1986 revealed that 23 per cent of cases could be attributed to travel to Mexico, and 10 per cent to day care attendees and their household contacts.
S C, McCombie +3 more
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Host protein phosphorylation during "Shigella flexneri" infection : a phosphoproteomic based systems biology approach [PDF]
, 2015 The enteroinvasive bacterium Shigella flexneri triggers its uptake into epithelial cells by injecting several effector proteins via its type three secretion system (TTSS) and interferes with various host cell processes at later stages of infection.
Schmutz, Christoph
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Elucidation of a molecular mechanism controlling inflammation during bacterial infection [PDF]
, 2015 Recently we described a mechanism of gap junction-mediated communication between infected and uninfected epithelial cells that potentiates innate immunity during infection by the enteroinvasive bacterium Shigella flexneri.
Tschon, Therese
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mSphere, 2020 Shigella flexneri is a major cause of bacillary dysentery in Beijing, China. The genetic features and population structure of locally circulating clones remained unclear. In this study, we sequenced the genomes of 93 S. flexneri isolates from patients in
Lang Yang +8 more
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Formate Promotes
mBio, 2018 The intracellular human pathogen Shigella flexneri invades the colon epithelium, replicates to high cell density within the host cell, and then spreads to adjacent epithelial cells. When S.
Benjamin J. Koestler +2 more
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Identification and Molecular Characterisation of a Novel Mu-Like Bacteriophage, SfMu, of Shigella flexneri. [PDF]
PLoS ONE, 2015 S. flexneri is the leading cause of bacillary dysentery in the developing countries. Several temperate phages originating from this host have been characterised. However, all S. flexneri phages known to date are lambdoid phages, which have the ability to
Richa Jakhetia, Naresh K Verma
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Frontiers in Bioengineering and Biotechnology, 2022 Shigella flexneri is a serious threat to global public health, and a rapid detection method is urgently needed. The CRISPR/Cas (clustered regularly interspaced short palindromic repeats/CRISPR-associated) system is widely used in gene editing, gene ...
Yaoqiang Shi +9 more
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Bacteriophage Sf6 Tailspike Protein for Detection of Shigella flexneri Pathogens [PDF]
, 2018 International audienceBacteriophage research is gaining more importance due to increasing antibiotic resistance. However, for treatment with bacteriophages, diagnostics have to be improved.
Mulard, Laurence, S +17 more
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