Plasmid Profile, Antibiotic Resistance, and Phenotypic Virulent Strains of S. flexneri [PDF]
Shigellosis is an acute gastroenteritis caused by Shigella species. The purpose of this study was to determine plasmid profile, antibiotic resistance and phenotypic virulent by Congo red between S. flexneri strains.
J Nowroozi, M Hakemi vala
doaj +5 more sources
Altering Trends in the Dominance of Shigella flexneri Serotypes and Emergence of Serologically Atypical S. flexneri Strains in Dhaka, Bangladesh [PDF]
ABSTRACT Of 469 recently isolated Shigella flexneri strains, 452 agglutinated with Shigella flexneri -specific monoclonal antibodies. Of these, 396 could be assigned to 10 of the currently recognized 15 serotypes, with S. flexneri 2b dominating (23.2%).
K A, Talukder +9 more
openaire +3 more sources
Saccharomyces boulardii as effective probiotic against Shiegella flexneri in mice [PDF]
This study was designed to evaluate the ability of Saccharomyce buolardi as effective probiotic against Shiegella flexneri. Mice treated with S. boulardii and infected with Sh.
Nedhaal S. Zbar +2 more
doaj +2 more sources
Finding potential drug targets against Shigella flexneri through druggable proteome exploration. [PDF]
:Background: Shigella flexneri is a gram negative bacteria that causes the infectious disease ‘shigellosis’. Shigella flexneri (S. flexneri) is responsible for developing diarrhea, fever and stomach cramps in human.
Mohammad Uzzal Hossain +6 more
doaj +2 more sources
The type 3 secretion effector IpgD promotes S. flexneri dissemination. [PDF]
The bacterial pathogen Shigella flexneri causes 270 million cases of bacillary dysentery worldwide every year, resulting in more than 200,000 deaths. S. flexneri pathogenic properties rely on its ability to invade epithelial cells and spread from cell to cell within the colonic epithelium.
Köseoğlu VK, Jones MK, Agaisse H.
europepmc +5 more sources
Complete genome sequence of
Background Shigella bacteria cause dysentery, which remains a significant threat to public health. Shigella flexneri is the most common species in both developing and developed countries.
Xue Ying +15 more
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Development of Shigella conjugate vaccines targeting Shigella flexneri 2a and S. flexneri 3a using a simple platform-approach conjugation by squaric acid chemistry. [PDF]
There is a need for vaccines effective against shigella infection in young children in resource-limited areas. Protective immunity against shigella infection targets the O-specific polysaccharide (OSP) component of lipopolysaccharide. Inducing immune responses to polysaccharides in young children can be problematic, but high level and durable responses
Kelly M +19 more
europepmc +3 more sources
Impact of O-Acetylation on S. flexneri 1b and 2a O-Antigen Immunogenicity in Mice. [PDF]
Shigellosis is a diarrheal disease caused prevalently by Shigella flexneri and S. sonnei and representing a major global health risk, particularly in developing countries. Bacterial O-antigen (OAg) is the primary target of the host immune response and modifications of its oligosaccharide units, including O-acetylation, are responsible for the ...
Arato V +5 more
europepmc +5 more sources
Computer-aided engineering of a branching sucrase for the glucodiversification of a tetrasaccharide precursor of S. flexneri antigenic oligosaccharides. [PDF]
AbstractEnzyme engineering approaches have allowed to extend the collection of enzymatic tools available for synthetic purposes. However, controlling the regioselectivity of the reaction remains challenging, in particular when dealing with carbohydrates bearing numerous reactive hydroxyl groups as substrates.
Benkoulouche M +12 more
europepmc +6 more sources
Key residues of S. flexneri OmpA mediate infection by bacteriophage Sf6. [PDF]
Many viruses, including bacteriophage, have the inherent ability to utilize several types of proteinaceous receptors as an attachment mechanism to infect cells, yet the molecular mechanisms that drive receptor binding have not been elucidated. Using bacteriophage Sf6 and its host, Shigella flexneri, we investigated how Sf6 utilizes outer membrane ...
Porcek NB, Parent KN.
europepmc +4 more sources

