Results 81 to 90 of about 19,689,673 (253)

The FsrA‐Mediated Iron‐Sparing Response Regulates the Biosynthesis of the Epipeptide EPE in Bacillus subtilis

Molecular Microbiology, EarlyView.
Under iron‐limited conditions, FsrA base‐pairs with the intergenic region between epeX and epeE, enhancing epeE translation and triggering EPE production. Toxin‐mediated cell lysis releases nutrients, including iron, which can be taken up by surviving cells.
Sarah Miercke, Rabea Ghandour, Kai Papenfort, Thorsten Mascher   +3 more
wiley   +1 more source

Antimicrobial resistance patterns and prevalence of class 1 and 2 integrons in Shigella flexneri and Shigella sonnei isolated in Uzbekistan

Gut Pathogens, 2010
Background Shigella is a frequent cause of bacterial dysentery in the developing world. Treatment with effective antibiotics is recommended for shigellosis, but options become limited due to globally emerging resistance.
Madiyarov Ruslan S, Bektemirov Amir M, Ibadova Gulnara A, Abdukhalilova Gulnara K, Khodiev Aybek V, Bodhidatta Ladaporn, Sethabutr Orntipa, Mason Carl J   +7 more
doaj   +1 more source

Vaccine Candidates Designed to Prevent Enterotoxigenic Escherichia coli Diarrhoea: A Scoping Review of Clinical Trials Evaluating Vaccine Candidates in Development

Tropical Medicine &International Health, EarlyView.
ABSTRACT Objectives The primary objectives of this study are to (1) summarise the current landscape of ETEC vaccine development by describing, characterising and comparing ETEC vaccine candidates in clinical development, (2) assess key characteristics of the phases 1, 2 and 3 clinical trials that have been designed to evaluate ETEC vaccines in ...
Vaidehi Nafade, Naheemot O. Sule, Yang Zhang, Angelina Sassi, Nicole E. Basta   +4 more
wiley   +1 more source

Genesis of a novel Shigella flexneri serotype by sequential infection of serotype-converting bacteriophages SfX and SfI

BMC Microbiology, 2011
Background Shigella flexneri is the major pathogen causing bacillary dysentery. Fifteen serotypes have been recognized up to now. The genesis of new S. flexneri serotypes is commonly mediated by serotype-converting bacteriophages.
Sun Qiangzheng, Lan Ruiting, Wang Yiting, Wang Jianping, Luo Xia, Zhang Shaomin, Li Peijing, Wang Yan, Ye Changyun, Jing Huaiqi, Xu Jianguo   +10 more
doaj   +1 more source

Changing epidemiology of shigellosis in Taiwan, 2010-2019: an emerging threat to HIV-infected patients and men who have sex with men

Emerging Microbes and Infections, 2022
Shigellosis appears to increase in certain at-risk populations in developed countries. Based on the nationwide surveillance, the annual incidence of shigellosis in Taiwan (1999-2019) was 0.38-5.77 cases per 100,000 people.
Chin-Shiang Tsai, Kuan-Yin Lin, Bo-Huang Liou, Chien-Shun Chiou, Yi-Chun Lin, Yuan-Ti Lee, Chia-Jui Yang, Hung-Jen Tang, Ying-Shu Liao, Chun-Eng Liu, Chen-Hsiang Lee, Po-Liang Lu, Sung-Hsi Huang, Chien-Ching Hung, Wen-Chien Ko, on behalf of the Taiwan HIV Study Group   +15 more
doaj   +1 more source

Ricinus Communis: Nutritional Importance, Health Benefits, and Industrial Applications

eFood, Volume 7, Issue 1, February 2026.
The current paper summarizes the nutritional composition, phytochemistry, health benefits, safety studies, and applications of castor beans and their oil. Moreover, the diverse bioactive compounds, including saponins, emodins, terpenoids, anthraquinones, flavonoids, steroids, and alkaloids, exhibit therapeutic properties such as antioxidant, anticancer,
Hassan Raza, Muhammad Tauseef Sultan, Asad Abbas, Aimen Mazhar, Ahmad Mujtaba Noman, Muhammad Imran, Muzzamal Hussain, Ehab M. Mostafa, Ahmed H. El‐Ghorab, Mohammed M. Ghoneim, Samy Selim, Mohamed A. Abdelgawad, Anjuman Gul Memon, Entessar Al Jbawi   +13 more
wiley   +1 more source

Virulence-Related Gene Distribution Among Shigella Isolates in Anhui, China: The Association with Antimicrobial Resistance

Infection and Drug Resistance, 2020
Yanyan Liu,1– 3,* Weihua Shen,4,* Yating Sun,1,* Na Lv,1 Kaili Sun,5 Lifen Hu,1 Ying Ye,1– 3 Yufeng Gao,1– 3 Jiabin Li1– 3,5 1Department of Infectious Diseases, The First Affiliated Hospital of Anhui Medical University, Hefei ...
Liu Y, Shen W, Sun Y, Lv N, Sun K, Hu L, Ye Y, Gao Y, Li J   +8 more
doaj  

Mitochondria mediate septin cage assembly to promote autophagy of Shigella [PDF]

, 2016
Septins, cytoskeletal proteins with well-characterised roles in cytokinesis, form cage-like structures around cytosolic Shigella flexneri and promote their targeting to autophagosomes.
Buranyi, S, Culley, S, Galea, D, Henriques, R, Hollinshead, M, Krokowski, S, Larrouy-Maumus, G, Lobato-Márquez, D, Mostowy, S, Pfanzelter, J, Sancho-Shimizu, V, Sirianni, A, Way, M, Willis, A   +13 more
core  

Inflammasomes: caspase-1-activating platforms with critical roles in host defense [PDF]

, 2011
Activation of the inflammatory cysteine protease caspase-1 in inflammasome complexes plays a critical role in the host response to microbial infections.
Lieselotte eVande Walle, Lieselotte eVande Walle, Mohamed eLamkanfi, Mohamed eLamkanfi   +3 more
core   +2 more sources

Porin‐Independent Uptake of Small Molecule Antibiotics Facilitated by Escherichia coli Outer Membrane Vesicles

Biotechnology and Bioengineering, Volume 123, Issue 1, Page 235-244, January 2026.
We demonstrate that bacterial outer membrane vesicles (OMVs) can enhance antibiotic delivery into Gram‐negative bacteria by bypassing porin‐dependent uptake. Encapsulation of imipenem in OMVs significantly increased its effectiveness against multidrug‐resistant clinical isolates, highlighting OMVs as a promising platform for overcoming permeability ...
Meishan Wu, Rachael M. Harrower, Ziang Li, Angela C. Brown   +3 more
wiley   +1 more source