Results 101 to 110 of about 20,287,569 (319)

Exercise and Nutrition Prehabilitation Program During Preoperative Chemotherapy Followed by Esophagectomy in Older Patients With Esophageal Cancer: A Randomized Clinical Trial

Annals of Gastroenterological Surgery, EarlyView.
This prospective randomized trial evaluated whether prehabilitation, exercise and nutrition intervention, enhance skeletal muscle mass during neoadjuvant chemotherapy in older patients with esophageal cancer undergoing esophagectomy. We also investigated whether exercise alone was sufficient to increase skeletal muscle mass, and whether nutritional ...
Keijiro Sugimura, Takashi Kanemura, Tomohira Takeoka, Takahito Sugase, Norihiro Matsuura, Kazuyoshi Yamamoto, Masahiko Yano, Hiroshi Miyata   +7 more
wiley   +1 more source

Syndecan-1 Promotes Streptococcus pneumoniae Corneal Infection by Facilitating the Assembly of Adhesive Fibronectin Fibrils

mBio, 2020
Subversion of heparan sulfate proteoglycans (HSPGs) is thought to be a common virulence mechanism shared by many microbial pathogens. The prevailing assumption is that pathogens co-opt HSPGs as cell surface attachment receptors or as inhibitors of innate
Akiko Jinno, Atsuko Hayashida, Howard F. Jenkinson, Pyong Woo Park   +3 more
doaj   +1 more source

The oral commensal Streptococcus mitis shows a mixed memory Th cell signature that is similar to and cross-reactive with Streptococcus pneumoniae. [PDF]

PLoS ONE, 2014
BACKGROUND: Carriage of and infection with Streptococcus pneumoniae is known to predominantly induce T helper 17 (Th17) responses in humans, but the types of Th cells showing reactivity towards commensal streptococci with low pathogenic potential, such ...
Stian André Engen, Håkon Valen Rukke, Simone Becattini, David Jarrossay, Inger Johanne Blix, Fernanda Cristina Petersen, Federica Sallusto, Karl Schenck   +7 more
doaj   +1 more source

Regulation of neutrophilic inflammation by proteinase-activated receptor 1 during bacterial pulmonary infection [PDF]

, 2015
Neutrophils are key effector cells of the innate immune response to pathogenic bacteria, but excessive neutrophilic inflammation can be associated with bystander tissue damage.
Brown, JS, Chambers, RC, José, RJ, Mercer, PF, Sulikowski, MG, Williams, AE   +5 more
core   +1 more source

Streptococcus pneumoniae’s Virulence and Host Immunity: Aging, Diagnostics, and Prevention

Frontiers in Immunology, 2018
Streptococcus pneumoniae is an infectious pathogen responsible for millions of deaths worldwide. Diseases caused by this bacterium are classified as pneumococcal diseases. This pathogen colonizes the nasopharynx of its host asymptomatically, but overtime
Lavida R. K. Brooks, G. Mias
semanticscholar   +1 more source

Iptacopan for Immune Thrombocytopenia and Cold Agglutinin Disease: A Global Phase 2 Basket Clinical Trial

American Journal of Hematology, EarlyView.
ABSTRACT Iptacopan is a first‐in‐class, oral, selective inhibitor of complement factor B that has demonstrated positive efficacy across several complement‐driven diseases. Here we evaluate the efficacy and safety of iptacopan monotherapy in adult patients with primary immune thrombocytopenia (ITP) and primary cold agglutinin disease (CAD). We performed
Alexander Röth, Wilma Barcellini, Christine Ademokun, Junho Jang, Maria Luisa Lozano, David Valcarcel Ferreiras, Cristina Pascual‐Izquierdo, Shripad Chitnis, Sofiya Matviykiv, Alessandra Vitaliti, Chi Chen, Vasiliki Katsanou, Raghav Chawla, Hanny Al‐Samkari   +13 more
wiley   +1 more source

Vancomycin‐Functionalized Nanodelivery Systems for Antibacterial Tissue Engineering Scaffolds

Advanced NanoBiomed Research, EarlyView.
This review consolidates recent advancements in VAN nanoformulations, critically evaluating their design principles, release mechanisms, and efficacy profiles against resistant Gram‐positive pathogens. While promising in vitro and in vivo results have been demonstrated, the clinicaltranslation of these technologies necessitates further rigorous ...
Nima Beheshtizadeh, Mahsa Mohammadzadeh, Amir Abbas Seraji, Ali Pirsadeghi, Elham Zendedel, Maliheh Gharibshahian   +5 more
wiley   +1 more source

Prevalence, Antimicrobial Drug Resistance and Associated Risk Factors of Streptococcus Pneumoniae Bacteria Infection Among Under-Five Children With Acute Lower Respiratory Tract Infection Attending Sheik Hassan Yebere Referral Hospital, Jig-Jiga, Ethiopia

Infection and Drug Resistance, 2023
Surafel Mekuria,1 Daniel Tolossa,1 Tigist Abebe,1 Tahir Yousuf Nour,2 Addisu Tesfaye,1 Abdurahman Kedir Roble3 1Medical Laboratory Sciences Department, School of Medicine, College of Medicine and Health Science, Jig-Jiga University, Jig-Jiga, Ethiopia ...
Mekuria S, Tolossa D, Abebe T, Nour TY, Tesfaye A, Roble AK   +5 more
doaj  

Defining the mechanisms underlying reduced immunity to Streptococcus pneumoniae with age [PDF]

, 2016
The increase in the elderly population is impacting the social and economic aspects of the modern world as increasing longevity is not matched by an increasing healthy lifespan. Increased infections are a major component of ill health in old age.
Torrente Gonçalves, Mariana
core  

Carriage of Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis, and Staphylococcus aureus in Indonesian children: A cross-sectional study. [PDF]

, 2018
Streptococcus pneumoniae is an important cause of infection and commonly colonizes the nasopharynx of young children, along with other potentially pathogenic bacteria. The objectives of this study were to estimate the carriage prevalence of S. pneumoniae,
Dewi, NE, Dunne, EM, Fadlyana, E, Hinds, J, Indriyani, SAK, Kartasasmita, C, Mulholland, EK, Murad, C, Pell, CL, Rusmil, K, Satzke, C, Sudigdoadi, S, Tarigan, R, Watts, E, Yani, FF   +14 more
core   +3 more sources