Results 121 to 130 of about 22,695,467 (240)

Studying the Oncolytic Activity of Streptococcus pyogenes Strains Against Hepatoma, Glioma, and Pancreatic Cancer In Vitro and In Vivo

Microorganisms
Background: Cancer remains a leading cause of mortality globally. Conventional treatment modalities, including radiation and chemotherapy, often fall short of achieving complete remission, highlighting the critical need for novel therapeutic strategies ...
Anna N. Tsapieva, Alexander N. Chernov, Nadezhda V. Duplik, Anastasiya O. Morozova, Tatiana A. Filatenkova, Mariia A. Suvorova, Elena Egidarova, Elvira S. Galimova, Kseniya Bogatireva, Alexander N. Suvorov   +9 more
doaj   +1 more source

Possible Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infections (PANDAS) Presenting in Late Adolescence and Early Adulthood: A Case Series

Clinical Case Reports, Volume 14, Issue 11, November 2026.
ABSTRACT PANDAS‐like syndromes may rarely occur beyond childhood. Although these patients may meet criteria for PANS, recognizing a possible streptococcal‐triggered subgroup remains important for diagnosis, future biomarker discovery, and refinement of disease classification.
Tariq A. Madani, Fahd S. Alsallum, Ola H. Abudaowd, Salman T. Madani   +3 more
wiley   +1 more source

Activity of ceftibuten, cefaclor, azithromycin, clarithromycin, erythromycin and telithromycin against Streptococcus pyogenes clinical isolates with different genotypes and phenotypes

, 2005
Background: The growing number of macrolide-resistant strains of Streptococcus pyogenes represents an increasing worldwide problem. Macrolide resistance in S. pyogenes is mediated by several different genes, which determine different levels of resistance
S. Ripa, M. Prenna, C. Zampaloni, D. Petrelli, E. De Vecchi, L. Drago, L. A. Vitali   +6 more
core   +1 more source

Bacterial Agents and Their Multidrug‐Resistance Profile Among Patients Suspected of Bacterial Infections in Hakim Gizaw Hospital, Debre Berhan, Ethiopia: A Cross‐Sectional Study

Health Science Reports, Volume 9, Issue 11, November 2026.
ABSTRACT Background and Aims Antimicrobial resistance is a global threat. Bacteria showed higher resistance in Ethiopia, and up‐to‐date data on it is urgently required for effective interventions. This study aimed to determine occurrence of multi‐drug‐resistant (MDR) bacterial isolates among patients presented to Hakim Gizaw Hospital (HGH).
Tizazu Zenebe Zelelie, Ermias Endewunetu, Yosef Temesgen, Demissew Shenkute Gebreyes, Zenawork Sahile, Biniam Mekonnen, Getachew Bizuneh, Asrat Berihun, Berhanu Yitayew   +8 more
wiley   +1 more source

Is Streptococcus pyogenes a pathogen or passenger in uncomplicated acute sore throat? A systematic review and meta-analysis

International Journal of Infectious Diseases
Objectives: The objective was to estimate the probability that finding a Streptococcus pyogenes (Group A Streptococcus) in a throat swab in a patient with a sore throat reflects the aetiology. We also investigated to what extent this is influenced by age,
Patrycja Woldan-Gradalska, Wojciech Gradalski, Ronny K. Gunnarsson, Pär-Daniel Sundvall, Karin Rystedt   +4 more
doaj   +1 more source

Augmenting Middle‐Down Sequence Coverage With Trapped Ion Mobility Spectrometry

Journal of Mass Spectrometry, Volume 61, Issue 11, November 2026.
ABSTRACT Middle‐down proteomics has emerged as an attractive alternative to conventional bottom‐up workflows because it better preserves sequence information and can annotate concurrent post‐translational modifications (PTMs). This is facilitated by a limited proteolysis step, which generates larger polypeptides than those typically found in bottom‐up ...
Rachitha S. Reddy, Nicholas B. Borotto
wiley   +1 more source

Inhibition of Streptococcus pyogenes biofilm by Lactiplantibacillus plantarum and Lacticaseibacillus rhamnosus

mSphere
The human pathobiont Streptococcus pyogenes forms biofilms and causes infections, such as pharyngotonsillitis and necrotizing fasciitis. Bacterial biofilms are more resilient to antibiotic treatment, and new therapeutic strategies are needed to control ...
Alejandro Gómez-Mejia, Mariano Orlietti, Andrea Tarnutzer, Srikanth Mairpady Shambat, Annelies S. Zinkernagel   +4 more
doaj   +1 more source

Increased Pediatric Head and Neck Abscesses Following the COVID‐19 Pandemic

The Laryngoscope, Volume 136, Issue 11, Page 5062-5071, November 2026.
This study evaluated the impact of the COVID‐19 pandemic on pediatric head and neck abscesses at two tertiary care centers. Overall head and neck abscess incidence increased more than threefold in the post‐pandemic period compared with the pre‐pandemic period, with increases observed across all major abscess subtypes.
Marco DiBlasi, Ryan C. Higgins, Nicole Welch, Dwight Jones, Arthur J. Chang   +4 more
wiley   +1 more source

Motif analysis of modified bases from PacBio SMRT sequencing in wild type S. pyogenes strain MEW123.

, 2019
Motif analysis of modified bases from PacBio SMRT sequencing in wild type S. pyogenes strain MEW123.
Kristin M. Jacob (6848618), Lyle A. Simmons (229769), Taylor M. Nye (6848615), Suzanne Dawid (191413), Elena K. Holley (6848621), Juan M. Nevarez (6848624), Michael E. Watson Jr. (6848627)   +6 more
core   +1 more source

A positive, growth-based PAM screen identifies noncanonical motifs recognized by the S. pyogenes Cas9. [PDF]

Sci Adv, 2020
Collias D, Leenay RT, Slotkowski RA, Zuo Z, Collins SP, McGirr BA, Liu J, Beisel CL.   +7 more
europepmc   +1 more source