Results 81 to 90 of about 22,695,467 (240)

Biological Characterization and Inhibition of Streptococcus pyogenes ZUH1 Causing Chronic Cystitis by Crocus sativus Methanol Extract, Bee Honey Alone or in Combination with Antibiotics: An In Vitro Study

Molecules, 2019
Streptococcus pyogenes (S. pyogenes) ZUH1 was isolated and characterized using morphological, cultural and biochemical methods. The results showed that the marker genes (namely spyCEP, ssa, sic, sdaB and speG) indicating group A streptococci (GAS) were ...
Seham Abdel-Shafi, Abdul-Raouf Al-Mohammadi, Sara Hamdi, Ahmed H. Moustafa, Gamal Enan   +4 more
doaj   +1 more source

Enhanced CRISPR‐cas systems for genome editing and molecular diagnostics

Interdisciplinary Medicine, EarlyView.
This review systematically summarizes the major optimization strategies for CRISPR‐Cas systems, focusing on the engineering of Cas proteins, guide RNAs, reporter probes, and the incorporation of chemical additives. The aim is to enhance editing precision and diagnostic capability, thereby expanding the CRISPR system's potential for broader biomedical ...
Sheng Li, Han Li, Bojie Chen, Ling Jiang, Keyu Long, Jiaqi Lang, Xingxiang Pu, Erhu Xiong   +7 more
wiley   +1 more source

Immune cell infiltrate after infection with S. pyogenes.

, 2016
Representative histology micrographs of infected skin from CD68(bcl2)tg mice and littermate controls from mice infected with S. pyogenes 2 days after infection (A).
Thomas Decker (158226), Nina Gratz (220538), Amanda M. Jamieson (177599), Lester Kobzik (82385), Pia Gamradt (3545000), Sandra Högler (3170268), Kellyanne Duncan (1692391), Pavel Kovarik (220565), Yun Xu (139234)   +8 more
core   +1 more source

Diverse Uses of Lantibiotics: Exploring New Approaches to Combat Antibiotic Resistance

Medicine Advances, EarlyView.
This review illustrates lantibiotics as an alternative therapeutic approach to combat antibiotic resistance, highlighting their diverse sources, including plants, insects, animals, and microorganisms. It further emphasizes their broad therapeutic potential, including antibacterial, antifungal, antiparasitic, antiviral, and anticancer activities (GA ...
Gopalarethinam Janani, Shangavy Pandiarajan, Kunal Biswas, Manickam Rajkumar, Agnishwar Girigoswami, Koyeli Girigoswami   +5 more
wiley   +1 more source

CRISPR-Cas in Streptococcus pyogenes

, 2019
The discovery and characterization of the prokaryotic CRISPR-Cas immune system has led to a revolution in genome editing and engineering technologies. Despite the fact that most applications emerged after the discovery of the type II-A CRISPR-Cas9 system
Charpentier, E., Le Rhun, A., Escalera-Maurer, A., Bratovič, M.   +3 more
core   +1 more source

Prime editing in neuropsychiatric disorders: From mutation‐specific target selection to clinical translation

Neuroprotection, EarlyView.
Abstract Prime editing, a novel clustered regularly interspaced short palindromic repeats (CRISPR)‐based technology, fuses a reverse transcriptase (RT) to an engineered CRISPR‐associated protein 9 (Cas9) and uses a prime editing guide RNA (pegRNA)‐encoded template.
Tianshan Ji, Yuan Zhang, Jinyi Zhao, Yiping Lu, Chengkun Wang   +4 more
wiley   +1 more source

Ruta graveolens L. in Evidence‐Based Phytotherapy: Pharmacological Activities, Bioactive Compounds and Safety

Phytotherapy Research, EarlyView.
Graphical representation of ethnomedical uses, major bioactive compounds, pharmacological potential and toxicological risks of Ruta graveolens L. ABSTRACT Ruta graveolens L. is widely used in traditional European, Asian, African, and South American medicine for digestive, nervous, cardiovascular, respiratory, and reproductive disorders.
Tetiana Serhiienko, Victoriya Georgiyants, Liudas Ivanauskas, Olha Mykhailenko   +3 more
wiley   +1 more source

Molecular Methods Enhance the Detection of Pyoderma-Related Streptococcus pyogenes and emm-Type Distribution in Children [PDF]

BACKGROUND: Streptococcus pyogenes-related skin infections are increasingly implicated in the development of rheumatic heart disease (RHD) in lower-resource settings, where they are often associated with scabies. The true prevalence of S pyogenes-related
Keeley, AJ, Armitage, EP, Angyal, A, Turner, CE, Senghore, E, Marks, M, de Silva, TI, Camara, J, Barry, M, Bah, S, McCarthy, JS, Smeesters, P, Hall, JN, Darton, TC, Darboe, S   +14 more
core   +4 more sources

Sinergismo in vitro tra rokitamicina e cotrimossazolo in S. pyogenes e S. pneumoniae

Microbiologia Medica, 2007
Background: Synergism between cotrimoxazole (SXT) and rokitamycin (ROK) was observed carrying out antimicrobial susceptibility tests on S. pyogenes and S. pneumoniae with the disk diffusion method (CLSI, 2005). The aim of this study was to confirm this phenomenon on a large number of isolates displaying different macrolide resistance phenotypes ...
Roveta S., MARCHESE, ANNA, DEBBIA, EUGENIO, Bandettini R.   +3 more
openaire   +5 more sources

Sulfur‐ and Selenium‐Decorated Coumarins: Synthetic Strategies Involving Cyclization and Late‐Stage Functionalization

The Chemical Record, EarlyView.
Two decades of synthetic strategies for sulfur‐, selenium‐decorated coumarins are critically surveyed through 44 literature reports, with particular emphasis on derivatives functionalized at the C‐3 and C‐4 positions. This review reports the direct construction of the coumarin framework through cyclization processes and late‐stage functionalization of ...
Bruna R. Schneider, Laura D. de Avila, Mauricio C. D. F. Xavier, Alex F. C. Flores, Liane K. Soares, Gabriel P. da Costa, Angelita M. Barcellos   +6 more
wiley   +1 more source