Results 91 to 100 of about 131,599 (329)

Structural and functional diversification in the teleost S100 family of calcium-binding proteins

BMC Evolutionary Biology, 2008
Background Among the EF-Hand calcium-binding proteins the subgroup of S100 proteins constitute a large family with numerous and diverse functions in calcium-mediated signaling.
Korsching Sigrun I, Saraiva Luis R, Kraemer Andreas M   +2 more
doaj   +1 more source

The adaptor protein CRK is a pro-apoptotic transducer of endoplasmic reticulum stress. [PDF]

, 2011
Excessive demands on the protein-folding capacity of the endoplasmic reticulum (ER) cause irremediable ER stress and contribute to cell loss in a number of cell degenerative diseases, including type 2 diabetes and neurodegeneration.
Austgen, Kathryn, Curran, Tom, Johnson, Emily T, Oakes, Scott A, Park, Tae-Ju   +4 more
core  

Engineering Tertiary Lymphoid Structures: Nanomedicine, Bioengineering, and Biomaterials for Precision Immunotherapy

Advanced NanoBiomed Research, EarlyView.
This review explains how biomaterials and nanoparticles can be used to induce or modulate tertiary lymphoid structures (TLSs), which are ectopic immune hubs that form in nonlymphoid tissues during chronic disease and cancer. By comparing different methods, the article highlights design principles for modeling TLSs or recapitulating specific TLS ...
Shaza Karaman, Mei ElGindi, Jeremy Teo
wiley   +1 more source

Protein S100 as outcome predictor after out-of-hospital cardiac arrest and targeted temperature management at 33 °C and 36 °C

Critical Care, 2017
Background We aimed to investigate the diagnostic performance of S100 as an outcome predictor after out-of-hospital cardiac arrest (OHCA) and the potential influence of two target temperatures (33 °C and 36 °C) on serum levels of S100.
Pascal Stammet, Josef Dankiewicz, Niklas Nielsen, François Fays, Olivier Collignon, Christian Hassager, Michael Wanscher, Johan Undèn, Jorn Wetterslev, Tommaso Pellis, Anders Aneman, Jan Hovdenes, Matt P. Wise, Georges Gilson, David Erlinge, Janneke Horn, Tobias Cronberg, Michael Kuiper, Jesper Kjaergaard, Yvan Gasche, Yvan Devaux, Hans Friberg, Target Temperature Management after Out-of-Hospital Cardiac Arrest (TTM) trial investigators   +22 more
doaj   +1 more source

Pancreatic cancer-associated diabetes mellitus: an open field for proteomic applications. [PDF]

, 2005
Background: Diabetes mellitus is associated with pancreatic cancer in more than 80% of the cases. Clinical, epidemiological, and experimental data indicate that pancreatic cancer causes diabetes mellitus by releasing soluble mediators which interfere ...
BALDO G, BASSO D, FLAGIELLO A, FOGAR P, GIUNCO S, GRECO E, NAVAGLIA F, PEDRAZZOLI S, PLEBANI M., PUCCI, PIETRO, VALERIO A, ZAMBON CF   +11 more
core   +1 more source

Review for "Recognition of S100 proteins by Signal Inhibitory Receptor on Leukocytes‐1 negatively regulates human neutrophils"

, 2021

openalex   +1 more source

Effect of diet type on serum and faecal concentration of S100/calgranulins in the captive cheetah [PDF]

, 2014
Gastrointestinal disease is omnipresent in captive cheetahs (Acinonyx jubatus), in contrast to its freeranging populations. The current study aimed to evaluate the effect of diet type (meat-only whole prey) on gastrointestinal health in captive cheetahs ...
Depauw, S, Heilmann, RM, Hesta, M, Janssens, GPJ, Steiner, JM, Suchodolski, JS, Whitehouse-Tedd, K   +6 more
core  

Physics of the saturation of particle acceleration in relativistic magnetic reconnection

, 2017
We investigate the saturation of particle acceleration in relativistic reconnection using two-dimensional particle-in-cell simulations at various magnetizations \sigma.
Kagan, Daniel, Nakar, Ehud, Piran, Tsvi
core   +1 more source

The S100 family is a prognostic biomarker and correlated with immune cell infiltration in pan-cancer

Discover Oncology
Background The S100 protein family is a group of small molecular EF-hand calcium-binding proteins that play critical roles in various biological processes, including promotion of growth, metastasis and immune evasion of tumor.
Xiaojie Liang, Xiaoshan Huang, Zihong Cai, Yeling Deng, Dan Liu, Jiayi Hu, Zhihao Jin, Xinyu Zhou, Hongsheng Zhou, Liang Wang   +9 more
doaj   +1 more source

STELLAR (Semantic Technologies Enhancing the Lifecycle of Learning Resources): Jisc Final Report [PDF]

, 2013
[Project Summary] As one of the earliest distance learning providers The Open University (OU) has a rich heritage of archived learning materials. An ever increasing amount of that is in digital form and is being deposited with the University Archive ...
Brown, Sarah, Nurse, Richard
core