Results 31 to 40 of about 131,599 (329)
S100s and HMGB1 Crosstalk in Pancreatic Cancer Tumors
Pancreatic cancer remains a disease that is very difficult to treat. S100 proteins are small calcium binding proteins with diverse intra- and extracellular functions that modulate different aspects of tumorigenesis, including tumor growth and metastasis.
Angelo Mandarino +5 more
doaj +1 more source
Certainty of S100 from Physiology to Pathology [PDF]
S100 exists in wide variety of tissues and cell types, originally isolated from brain tissue and they are of low molecular weight proteins. S100 is evenly distributed in cytoplasm and also in nucleoplasm and is involved in both intercellular and ...
Puneeth Horatti Kuberappa +4 more
doaj +1 more source
Evaluation of liposomes coated with a pH responsive polymer [PDF]
Liposomes have been coated with the pH responsive polymer, Eudragit S100, and the formulation's potential for lower gastrointestinal (GI) targeting following oral administration assessed.
Barea, M.J. +3 more
core +1 more source
Melanoma mimicking malignant peripheral nerve sheath tumor with spread to the cerebellopontine angle: Utility of next-generation sequencing in diagnosis [PDF]
Cutaneous spindle cell malignancy is associated with a broad differential diagnosis, particularly in the absence of a known primary melanocytic lesion.
Birinyi, Paul +6 more
core +3 more sources
RAGE Signaling in Skeletal Biology [PDF]
PURPOSE OF REVIEW: The receptor for advanced glycation end products (RAGE) and several of its ligands have been implicated in the onset and progression of pathologies associated with aging, chronic inflammation, and cellular stress. In particular, the
Davis, Hannah M. +2 more
core +2 more sources
Exclusive neuronal expression of SUCLA2 in the human brain [PDF]
SUCLA2 encodes the ATP-forming subunit (A-SUCL-) of succinyl-CoA ligase, an enzyme of the citric acid cycle. Mutations in SUCLA2 lead to a mitochondrial disorder manifesting as encephalomyopathy with dystonia, deafness and lesions in the basal ganglia ...
A Kowluru +55 more
core +2 more sources
A Case Report on a Rare Entity: Nerve Sheet Myxoma
Nerve sheath myxoma is a rare benign tumor of peripheral nerve sheath origin arises from the Schwann cell. In 1969 Harkin and Reed first reported a case of Nerve sheath myxoma.
Margaret Theresa J +4 more
doaj +1 more source
Multifunctional Role of S100 Protein Family in the Immune System: An Update
S100 is a broad subfamily of low-molecular weight calcium-binding proteins (9–14 kDa) with structural similarity and functional discrepancy. It is required for inflammation and cellular homeostasis, and can work extracellularly, intracellularly, or both.
Parul Singh, Syed Azmal Ali
doaj +1 more source
Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death. [PDF]
Apoptosis is a genetically regulated cell suicide programme mediated by activation of the effector caspases 3, 6 and 7. If apoptotic cells are not scavenged, they progress to a lytic and inflammatory phase called secondary necrosis.
Alnemri, Diana +5 more
core +2 more sources
Cutaneous leiomyosarcoma with osteoid metaplasia was diagnosed at the base of the right wing in a five-year-old female budgerigar. Grossly, the tumour mass was well circumscribed and solitary, and had a nodular appearance on section.
N. Timurkaan +3 more
doaj +1 more source

