Results 111 to 120 of about 38,415 (238)

Recent progress on the development of hydrogel‐based microneedles for transdermal drug delivery

VIEW, EarlyView.
This study provides a comprehensive and up‐to‐date analysis of recent progress in HMN technology, covering fundamental transdermal delivery mechanisms and design principles, biomaterials used in HMN fabrication, drug loading and release strategies, and emerging therapeutic applications.
Mohammad Muhtasim Ittisaf, Salman Farsi Taharat, Md. Sadek Miah, Hasan Tasnim Salehin, M. Azam Ali, Shoeb Ahmed   +5 more
wiley   +1 more source

Specific S100 Proteins Bind Tumor Necrosis Factor and Inhibit Its Activity. [PDF]

Int J Mol Sci, 2022
Kazakov AS, Zemskova MY, Rystsov GK, Vologzhannikova AA, Deryusheva EI, Rastrygina VA, Sokolov AS, Permyakova ME, Litus EA, Uversky VN, Permyakov EA, Permyakov SE.   +11 more
europepmc   +1 more source

Peritoneal Fluid‐Derived Small Extracellular Vesicle Proteins as Potential Biomarkers for Endometriosis: A Case–Control Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To demonstrate the presence of peritoneal fluid (PF)‐derived small extracellular vesicles (sEVs) in endometriosis and control samples, to characterise their protein content and to define endometriosis‐specific biomarkers within the sEV proteome. Design Case–control experimental study. Setting Academic endometriosis centre.
Hannah M. Nazri, Roman Fischer, Joel Steele, Sanjiv Manek, Kavita S. Subramaniam, Benedikt M. Kessler, Krina T. Zondervan, Thomas T. Tapmeier, Christian M. Becker   +8 more
wiley   +1 more source

S100 Proteins as Novel Therapeutic Targets in Psoriasis and Other Autoimmune Diseases. [PDF]

Molecules, 2022
Kurpet K, Chwatko G.
europepmc   +1 more source

Sodium Diclofenac‐Loaded Drug Delivery Microspheres: Impact on Calcium Hydroxide Paste Properties and Biological Response

Australian Endodontic Journal, EarlyView.
ABSTRACT This study evaluated whether the incorporation of sodium diclofenac‐loaded microspheres into a calcium hydroxide paste enhances antibiofilm activity while maintaining physicochemical properties and biocompatibility. Calcium hydroxide paste, calcium hydroxide combined with sodium diclofenac, and calcium hydroxide containing sodium diclofenac ...
João Vitor Oliveira de Amorim, Murilo Priori Alcalde, Leonardo Cabau, Rodrigo Ricci Vivan, Paulo Henrique Weckwerth, Marco Antonio Hungaro Duarte, Guilherme Ferreira da Silva   +6 more
wiley   +1 more source

CAV2 promotes the invasion and metastasis of head and neck squamous cell carcinomas by regulating S100 proteins. [PDF]

Cell Death Discov, 2022
Wang Y, Wang Y, Liu R, Wang C, Luo Y, Chen L, He Y, Zhu K, Guo H, Zhang Z, Zhang Z, Luo J.   +11 more
europepmc   +1 more source

Distinct Gene Expression Profiles of Ara h 2‐Specific B Cells in Desensitization and Tolerance During Peanut Oral Immunotherapy

Allergy, EarlyView.
Gene expression of Ara h 2‐specific B cells over the course of the peanut OIT. Isotype of allergen‐specific B cells changes through OIT towards IgG4. Peanut OIT changes the gene expression of allergen‐specific memory B cells. OIT patients showed increased gene expression for regulatory B cells and immune regulation.
Stephan R. Schneider, Juan‐Felipe López, Huseyn Babayev, Willem van de Veen, Minglin Yang, Cezmi A. Akdis, Kari Nadeau, Carolyn H. Baloh, Stacie M. Jones, Lisa M. Wheatley, Mübeccel Akdis, IMPACT, Amy M. Scurlock, D. Pesek, Joy Laurienzo‐Panza, Marshall Plaut, A. Wesley Burks, Edwin H. Kim, Mike Kulis, Anna Nowak‐Wegrzyn, Hugh A. Sampson, Julie Wang, Robert A. Wood, Sharon Chinthrajah, Robert Sayantani B. Sindher, Jacqueline Johnson, Katharine Spain, Denise C. Babineau, Hyunsook Chin, Rachel Yan, Don Whitehouse, Michelle L. Sever, Srinath Sanda, David Larson, Tielin Qin, Gina Marchesini, Kavitha Gilroy, Sylvia Posso, Sabrina Skiba, Thien‐Son Nguyen, Adam Wojno, Tuan Nguyen, Vivian Gersuk, Quynh‐Anh Nguyen, Jessica Garber, Kimberly O'Brien, Brandon Larson, C. Cousens‐Jacobs, Alex Hu   +48 more
wiley   +1 more source

The Anti‐Inflammatory Effect of Normothermic Machine Perfused Human Kidneys on Monocyte‐Derived Dendritic Cells

Artificial Organs, EarlyView.
The immunogenicity of donor kidneys on NMP can be studied using monocyte‐derived dendritic cells. Incubation with perfusate showed an anti‐inflammatory dendritic cell phenotype and function that suggests the release of an anti‐inflammatory factor or factors during NMP. ABSTRACT Background The immunomodulatory activity of normothermic machine perfusion (
Laura W. D. Knijff, Asel S. Arykbaeva, Sandra W. van der Kooij, Dorottya K. de Vries, Mieke F. van Essen, Ian P. J. Alwayn, Henri G. D. Leuvenink, Rutger J. Ploeg, Cees van Kooten   +8 more
wiley   +1 more source

From patient to tumor organoid: Culture protocol choice controls glioblastoma tumor architecture and identity

Brain Pathology, EarlyView.
How glioblastoma organoids are made shapes what they become. Fragment‐based cultures preserve extracellular matrix networks, cellular diversity, and primary tumor identity, whereas dissociation‐based cultures shift toward growth‐adapted states and simplified microenvironments. Abstract Patient‐derived tumor organoids are widely used in cancer research,
Jana Slovackova, Ondrej Bernatik, Katarina Cimborova, Martin Barak, Michal Hendrych, Karolina Kocourkova, Marie Sulcova, Jaroslav Olha, Katerina Amruz Cerna, Zdenek Hodny, Radim Jancalek, Dasa Bohaciakova   +11 more
wiley   +1 more source

Recognition of S100 proteins by Signal Inhibitory Receptor on Leukocytes-1 negatively regulates human neutrophils. [PDF]

Eur J Immunol, 2021
Rumpret M, von Richthofen HJ, van der Linden M, Westerlaken GHA, Talavera Ormeño C, Low TY, Ovaa H, Meyaard L.   +7 more
europepmc   +1 more source