Results 11 to 20 of about 15,017 (189)

S100A10, a novel biomarker in pancreatic ductal adenocarcinoma [PDF]

Molecular Oncology, 2018
Pancreatic cancer is arguably the deadliest cancer type. The efficacy of current therapies is often hindered by the inability to predict patient outcome.
Weei-Yuarn Huang, Ian C G Weaver, Hong Gu   +2 more
exaly   +5 more sources

Assessment of the cellular localisation of the annexin A2/S100A10 complex in human placenta [PDF]

Journal of Molecular Histology, 2018
The AnxA2/S100A10 complex has been implicated in various placental functions but although the localisation of these proteins individually has been studied, there is no information about the localisation of their complex in situ at the cellular level ...
Seham A Abd El-Aleem, Lodewijk V Dekker
exaly   +5 more sources

REGULATION OF FIBRINOLYSIS BY S100A10 IN VIVO [PDF]

Blood, 2011
Endothelial cells form the inner lining of vascular networks and maintain blood fluidity by inhibiting blood coagulation and promoting blood clot dissolution (fibrinolysis).
Surette, Alexi P.
core   +4 more sources

Identification of regions responsible for the open conformation of S100A10 using chimaeric S100A11–S100A10 proteins

Biochemical Journal, 2011
S100A11 is a dimeric EF-hand calcium-binding protein. Calcium binding to S100A11 results in a large conformational change that uncovers a broad hydrophobic surface used to interact with phospholipid-binding proteins (annexins A1 and A2) and facilitate ...
Gary S. Shaw, Liliana Santamaria-Kisiel
core   +6 more sources

Mechanism of plasmin generation by S100A10

Thrombosis and Haemostasis, 2017
Plasminogen (Pg) is cleaved to form plasmin by the action of specific plasminogen activators such as the tissue plasminogen activator (tPA). Although the interaction of tPA and Pg with the surface of the fibrin clot has been well characterised, their ...
Ain Adilliah Kamaludin, Sharma, Vandna, Girish Sahni, Sahni, Girish, Thelwell, Craig, Madureira, Patricia, Miller, Victoria A., Longstaff, Colin, Madureira, Patricia A., Thewell, Craig, Victoria A. Miller, Waisman, David M., Jeffrey Komar, Patricia A. Madureira, Craig Thelwell, David M. Waisman, Kamaludin, Ain Adilliah, Vandna Sharma, Colin Longstaff, Komar, Jeffrey   +19 more
core   +4 more sources

EGCG-loaded nanoparticles attenuate post-SAH white matter injury by targeting HO-1/S100A10 to suppress oxidative stress-induced reactive astrocytes. [PDF]

Redox Rep
Objective Subarachnoid hemorrhage (SAH) is associated with high mortality and poor outcomes, which are closely related to white matter injury (WMI).
Lang D, Zheng Y, Zhang J, Li Z, Niu M, Wang J, Wang X, Huang L, Xue J, Li L, Chen Y.   +10 more
europepmc   +2 more sources

Optimized transformation, overexpression and purification of S100A10 [PDF]

BioTechniques, 2019
As a member of the S100 protein family, S100A10 has already been purified. However, its purity, or even yield, have often not been reported in the literature. To facilitate future biophysical experiments with S100A10, we aimed to obtain it at a purity of
Xiaolin Yan, Marie-France Lebel-Beaucage, Samuel Tremblay, Gary S Shaw, Line Cantin, Elodie Boisselier   +5 more
core   +4 more sources

RAN-S100A10-EGFR axis facilitates papillary thyroid cancer metastasis by PI3K/AKT signaling. [PDF]

Cell Death Dis
Background: The incidence of thyroid cancer has been increasing in recent years, with papillary thyroid carcinoma (PTC) accounting for the majority of cases.
Song W, Liu Z, Shi C, Wang G, He L, Chen Z, Li Y, Yu Y, Jiang R, Wang X, Zhao K, Chen Z, Tian Y, Qi F, Wang Y, He X.   +15 more
europepmc   +2 more sources

S100A10 Promotes Pancreatic Ductal Adenocarcinoma Cells Proliferation, Migration and Adhesion through JNK/LAMB3-LAMC2 Axis

Cancers, 2022
Simple Summary Despite the advance in therapeutic strategy, the prognosis of pancreatic ductal adenocarcinoma (PDAC) is still unsatisfactory, with a 5-year survival rate of less than 9%. As a member of the S100 protein family, S100A10 has been identified
Hai Lin, Pengfei Yang, Bixiang Li, Yue Chang, Yutong Chen, Yaning Li, Kecheng Liu, Xinyue Liang, Tian-rui Chen, Yalan Dai, Wenzheng Pang, L. Zeng   +11 more
semanticscholar   +2 more sources

S100A10 (S100 calcium binding protein A10) [PDF]

Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2009
Review on S100A10 (S100 calcium binding protein A10), with data on DNA, on the protein encoded, and where the gene is ...
Madureira, PA, Waisman, DM
core   +3 more sources