Results 31 to 40 of about 15,017 (189)
Clinical significance of serum S100A10 in lung cancer [PDF]
Journal of International Medical Research, 2021 Objective To investigate the clinical significance of serum S100 calcium-binding protein A10 (S100A10) levels in lung cancer. Methods This prospective study enrolled patients with lung cancer, patients with benign lung nodules and ...
Yu-Lei Hou +3 more
openaire +3 more sources
Multiple functions of S100A10, an important cancer promoter [PDF]
Pathology International, 2019 The S100 group of calcium binding proteins is composed of 21 members that exhibit tissue/cell specific expressions. These S100 proteins bind a diverse range of targets and regulate multiple cellular processes, including proliferation, migration and differentiation.
Yuriko Saiki, Akira Horii
openaire +2 more sources
miR-21-5p Inhibits the Proliferation, Migration, and Invasion of Glioma by Targeting S100A10
Journal of Cancer, 2023 S100A10, a member of the S100 protein family, is upregulated in multiple human malignancies and plays a key role in regulating tumor progression.
P. Gao +7 more
semanticscholar +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2023 Significance When epithelial cells detach from the basal substratum and are extruded into the apical lumen, they will be subjected to physical stresses including the increased reactive oxygen species (ROS) and eventually undergo apoptosis.
S. Ito +18 more
semanticscholar +1 more source
Ca2+ ions facilitate the organization of the Annexin A2/S100A10 heterotetramer
Proteins: Structure, Function, and Bioinformatics, 2023 Annexin A2 (A2) is a member of the Annexin family, which contains Ca2+‐regulated phospholipid‐binding proteins. Annexins associate with S100 proteins to form heterotetramers.
S. Lindsay, L. Bartolotti, Yumin Li
semanticscholar +1 more source
Upregulation of S100A10 in metastasized breast cancer stem cells [PDF]
Cancer Science, 2020 AbstractMetastatic progression remains the major cause of death in human breast cancer. Cancer cells with cancer stem cell (CSC) properties drive initiation and growth of metastases at distant sites. We have previously established the breast cancer patient‐derived tumor xenograft (PDX) mouse model in which CSC marker CD44+ cancer cells formed ...
Hisano Yanagi +15 more
openaire +2 more sources
S100A10: A Key Regulator of Fibrinolysis [PDF]
, 2014 Regulation of fibrinolytic activity can be achieved by several mechanisms, ranging from regulating the production and localization of the plasminogen activators and their inhibitors, the degradation and inactivation of plasmin via autoproteolysis, and the synthesis and localization of the cell surface receptors for plasminogen.
Alexi P. Surette, David M. Waisman
openaire +1 more source
, 2023 Accaumulating studies focus on the effects of C3-positive A1-like phenotypes and S100A10-positive A2-like phenotypes of reactive astrocytes on spinal cord injury (SCI), however the origins and dynamic changes of C3- and S100A10-positive reactive ...
Yi-long Ren (17693733) +6 more
core +1 more source
, 2021 International audienceProtein S100A10 participates in different cellular mechanisms and has different functions, especially at the membrane. Among those, it forms a ternary complex with annexin A2 and the C-terminal of AHNAK and then joins the dysferlin ...
Kumar, Kiran +8 more
core +1 more source
The prognostic value of S100A10 expression in cancer.
Oncology letters, 2019 S100A10, a member of the S100 protein family, commonly forms a heterotetrameric complex with Annexin A2. This is essential for the generation of cellular plasmin from plasminogen, which leads to a cascade of molecular events crucial for tumor progression.
Tantyo, Normastuti Adhini +5 more
openaire +4 more sources