Results 121 to 130 of about 613,651 (294)

Detection and characterization of bovine coronavirus and rotavirus in calves in Ethiopia

BMC Veterinary Research
Background Bovine rotavirus A (BRVA) and bovine coronavirus (BCoV) cause significant diarrhea in young calves, leading to health issues and economic losses in the cattle industry.
Yisehak Tsegaye Redda, Haileeyesus Adamu, Julia Bergholm, Johanna F. Lindahl, Anne-Lie Blomström, Mikael Berg, Tesfaye Sisay Tessema   +6 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Additional file 4: Figure S1. of Genomic identification, characterization and differential expression analysis of SBP-box gene family in Brassica napus

, 2016
Phenotypes of two lines with different branch angle. (A) 6098B and Purler lines grown at the middle flowering stage. Bar = 25 cm. (B) The branch angle of 6098B is larger than that of Purler. The arrows indicate the different branch angle of two lines. Bar = 2 cm. (PPTX 145 kb)
Hongtao Cheng, Mengyu Hao, Wenxiang Wang, Desheng Mei, Chaobo Tong, Wang, Hui, Liu, Jia, Fu, Li, Hu, Qiong   +8 more
openaire   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Additional file 4: Table S1. of Functional characterization of thiolase-encoding genes from Xanthophyllomyces dendrorhous and their effects on carotenoid synthesis

, 2016
Primers designed and used for this work. (DOCX 107 kb)
Werner, Nicole, GĂłmez, Melissa, Baeza, Marcelo, VĂ­Ctor Cifuentes, AlcaĂ­No, Jennifer   +4 more
openaire   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Additional file 1: Table S1. of Cloning and characterization of an ABA-independent DREB transcription factor gene, HcDREB2, in Hemarthria compressa

, 2016
Primer used in isolating HcDREB2 gene. (DOCX 16Â kb)
Yongxia Chen, Linkai Huang, Haidong Yan, Xinquan Zhang, Xu, Bin, Ma, Xiao   +5 more
openaire   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Additional file 1: Table S1. of Genomic identification, characterization and differential expression analysis of SBP-box gene family in Brassica napus

, 2016
Primers used for quantitative polymerase chain reaction (qPCR) in gene expression analysis. (DOC 36 kb)
Hongtao Cheng, Mengyu Hao, Wenxiang Wang, Desheng Mei, Chaobo Tong, Wang, Hui, Liu, Jia, Fu, Li, Hu, Qiong   +8 more
openaire   +1 more source