Results 271 to 280 of about 2,654,829 (330)

Refined Transgenic Mouse Models Which Recapitulate the Natural Features of Chronic Wasting Disease With Rapid Prion Disease Onsets. [PDF]

J Infect Dis
DeFranco JP, Kim S, Atkinson ZN, Crowell J, Lei S, Bian J, Telling GC.   +6 more
europepmc   +1 more source

TriCON: A Carbon‐Based Triple‐Modal Nanoplatform for Pancreatic Cancer Therapy

Advanced Science, EarlyView.
We developed TriCON, a triple‐modality nanotherapeutic platform, to treat pancreatic ductal adenocarcinoma (PDAC) by synergizing gene editing, chemotherapy, and immunotherapy. TriCON utilizes CRISPR/Cas9 to target the poliovirus receptor (PVR), combined with nano‐encapsulated doxorubicin and checkpoint blockade. This approach achieved significant tumor
Xinyu Peng, Jiaxing Huang, Shengnan Lv, Jian Zhang, Liangliang Zhang, Huan Liu, Yan Liu, Zhen‐An Qiao, Feng Wei, Bao‐Lian Su   +9 more
wiley   +1 more source

Case Report: Multiple intra-abdominal lymph node abscesses due to <i>Staphylococcus aureus</i> in a cat. [PDF]

Front Vet Sci
Tamura K, Kushida K, Iwanaga T, Fukushima R, Ohmori K.   +4 more
europepmc   +1 more source

MDP25‐VDAC3 Complex Orchestrates Actin Remodeling and Mitochondrial Dynamics to Modulate Innate Immunity in Arabidopsis

Advanced Science, EarlyView.
This study reveals that actin remodeling regulates mitochondrial elongation as a defense strategy in plants. Flagellin perception induces fusion‐dependent elongation, supported by cortical actin bundles, to repair damage and boost ATP and ROS production.
Junxiu Hou, Pengfei Lu, Xuan Cui, Liangfeng Luo, Qing Pan, Jiejie Li   +5 more
wiley   +1 more source

Water for agriculture: implications for future policy and practice [PDF]

, 2010
Arnell, Nigel, Bailey, Alison, Charlton, Matthew   +2 more
core  

MicroRNA‐375‐3p Targets Fatty Acid Synthase and Relish to Regulate Energy Allocation During Pupal Metamorphosis and Starvation

Advanced Science, EarlyView.
During pupal metamorphosis and starvation, elevated 20‐hydroxyecdysone (20E) and suppressed insulin trigger Forkhead box O (FOXO) nuclear translocation, enhancing miR‐375‐3p expression. This downregulates fatty acid synthase (FASN) and Relish, promoting lipid breakdown for energy while prioritizing antioxidant responses over immune functions to support
Peng Chen, Meiqi Cheng, Jianhui Wang, Jing Tang, Xiaoqiao Huang, Yusi Li, Huiling Zhou, Ling Zhang, Yi Dong, Chengjun Li, Bin Li   +10 more
wiley   +1 more source

How has the global food governance system evolved, and what challenges does it currently pose for food systems transformation? A narrative review and synthesis of the literature. [PDF]

Global Health
Slater S, Lawrence M, Wood B, Nisbett N, Baker P.   +4 more
europepmc   +1 more source

Predicting Veterinary Career Intentions Using Motivational Characteristics: A Survey Study Among Hungarian Students. [PDF]

Vet Sci
Szücs L, Fehérvári P, Ózsvári L.
europepmc   +1 more source

Fosfomycin Resistance: An Update on the Anthropogenic Impact Through Agriculture. [PDF]

Pathogens
Goraj W, Kowalczyk P, Bełżecki G, Furtak A, Pytlak A, Szafranek-Nakonieczna A.   +5 more
europepmc   +1 more source