Results 261 to 270 of about 635,476 (340)

Structural analyses of ABA transporters give new impetus to the study of ABA regulation

Annals of Applied Biology, EarlyView.
Abscisic acid (ABA) regulates key physiological processes and coordinates abiotic stress responses. In the six decades since it was first described, a huge amount of work has been conducted on ABA synthesis, breakdown and signalling mechanisms. Recently, attention has been turned to the role of ABA transporters, and the elucidation in exquisite detail ...
Navneet Kaur, Natasha Brock, Nigel G. Halford   +2 more
wiley   +1 more source

The Biosynthesis of Carbamoyl Phosphate in Saccharomyces cerevisiae

, 1965
F. Lacroute, André Pierard, Marcelle Grenson, J.M. Wiame   +3 more
openalex   +1 more source

Interstitial stem cells in Hydra [PDF]

, 1987
Bosch, Thomas C. G., David, Charles N., Hobmayer, Engelbert, Holstein, Thomas W., Loomis, W. F., Schmidt, Tobias   +5 more
core  

Clinically relevant niclosamide concentrations modulate TMEM16A and CaV1.2 channels to control artery tone and capillary diameter

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose TMEM16A Ca2+‐gated Cl− channels mediate depolarisation of contractile vascular cells. The anthelmintic niclosamide was reported to modulate the TMEM16A channel, suggesting possible repurposing for vascular pharmacology. Here, we investigate the mechanism of TMEM16A modulation by niclosamide and explore its effect on the ...
Rachel Kaye, Claire Pearson, Tibyan Babiker, Emilio Agostinelli, Rumaitha Al‐Hosni, Paolo Tammaro   +5 more
wiley   +1 more source

Nano-enhanced biocarriers: ferric oxide-modified chitosan and calcium alginate beads for improved fermentation efficiency and reusability in a bubble column bioreactor. [PDF]

Biotechnol Lett
Abutu D, Aderemi BO, Ameh AO, Yussof HW, Agi A.   +4 more
europepmc   +1 more source

Compartmentalisation in cAMP signalling: A phase separation perspective

British Journal of Pharmacology, EarlyView.
Cells rely on precise spatiotemporal control of signalling pathways to ensure functional specificity. The compartmentalisation of cyclic AMP (cAMP) and protein kinase A (PKA) signalling enables distinct cellular responses within a crowded cytoplasmic space.
Milda Folkmanaite, Manuela Zaccolo
wiley   +1 more source

Metagenomics-based analysis of microbial community dynamics and flavor compound correlations during rice-flavor Baijiu brewing. [PDF]

Front Bioeng Biotechnol
Li Q, Zhang L, Li R, Tang J, Lin B, Qin C, Jiang W, An L, Zhang F, Shi X, Yang S, Yang Q, Chen S.   +12 more
europepmc   +1 more source

Saccharomyces cerevisiae Mub1, a substrate adaptor of E3 ubiquitin ligase Ubr2, modulates sensitivity to cell wall stressors through multiple transcription factors

The FEBS Journal, EarlyView.
We show that Mub1 links cell wall robustness with the ubiquitin‐proteasome system. As an adaptor protein of the E3 ubiquitin ligase Ubr2, it facilitates the ubiquitination of various transcription factors, including Mcm1 and Swi4. Yeasts evolved a complex regulatory programme to build and maintain their cell wall, the primary structure through which ...
Nada Šupljika, Antonia Paić, Ana Novačić, Tea Martinić Cezar, Béatrice Vallée, Renata Teparić, Igor Stuparević, Bojan Žunar   +7 more
wiley   +1 more source

Transcription‐coupled repair: tangled up in convoluted repair

The FEBS Journal, EarlyView.
In this review, we discuss recent findings derived from diverse genomic, biochemical and structural, imaging, and functional studies (B–E) that culminated in deep mechanistic insight (A) into the vital cellular process of transcription‐coupled nucleotide excision repair (TC‐NER).
Diana A. Llerena Schiffmacher, Yun Jin Pai, Alex Pines, Wim Vermeulen   +3 more
wiley   +1 more source

Conserved function of a RasGEF‐mediated pathway in the metabolic compensation of the circadian clock

The FEBS Journal, EarlyView.
Metabolic compensation of the circadian clock is essential for stabilizing the period of endogenous timekeeping in environments with significant nutrient fluctuations. In this study, we demonstrate that RasGEF (SOS1)‐mediated signaling, which is influenced by metabolic conditions, supports the robust function of the circadian clock under low glucose ...
Orsolya Sárkány, Anita Szőke, Aladár Pettkó‐Szandtner, Eszter Éva Kálmán, Michael Brunner, Norbert Gyöngyösi, Krisztina Káldi   +6 more
wiley   +1 more source