Results 321 to 330 of about 496,628 (371)

Saccharomyces cerevisiae Mub1, a substrate adaptor of E3 ubiquitin ligase Ubr2, modulates sensitivity to cell wall stressors through multiple transcription factors

open access: yesThe FEBS Journal, EarlyView.
We show that Mub1 links cell wall robustness with the ubiquitin‐proteasome system. As an adaptor protein of the E3 ubiquitin ligase Ubr2, it facilitates the ubiquitination of various transcription factors, including Mcm1 and Swi4. Yeasts evolved a complex regulatory programme to build and maintain their cell wall, the primary structure through which ...
Nada Šupljika   +7 more
wiley   +1 more source

Systematic Characterization and Analysis of the Freeze-Thaw Tolerance Gene Set in the Budding Yeast, <i>Saccharomyces cerevisiae</i>. [PDF]

open access: yesInt J Mol Sci
Hartnett D   +16 more
europepmc   +1 more source

Transcription‐coupled repair: tangled up in convoluted repair

open access: yesThe FEBS Journal, EarlyView.
In this review, we discuss recent findings derived from diverse genomic, biochemical and structural, imaging, and functional studies (B–E) that culminated in deep mechanistic insight (A) into the vital cellular process of transcription‐coupled nucleotide excision repair (TC‐NER).
Diana A. Llerena Schiffmacher   +3 more
wiley   +1 more source

New insights into Sti1/Hop's cochaperone function highlight the complexity of proteostatic regulation

open access: yesThe FEBS Journal, EarlyView.
Sti1/Hop functions extend beyond scaffolding in the Hsp70‐Hsp90 chaperone complex to sequester misfolded proteins during cell stress. Consequently, imbalances between levels of Sti1/Hop relative to the rest of the proteostasis machinery negatively affect fitness and stress resilience. Sti1/Hop is a cochaperone that regulates Hsp70 and Hsp90 chaperones.
Gregory Lloyd Blatch   +1 more
wiley   +1 more source

Production of borneol, camphor, and bornyl acetate using engineered <i>Saccharomyces cerevisiae</i>. [PDF]

open access: yesMetab Eng Commun
Tominaga M   +5 more
europepmc   +1 more source

Computational analysis of polymorphic residues in maltose and maltotriose transporters of a wild <i>Saccharomyces cerevisiae</i> strain. [PDF]

open access: yesOpen Life Sci
Faz-Cortez OA   +5 more
europepmc   +1 more source

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